Drosophila miranda: 108160453
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Entry
108160453 CDS
T06132
Name
(RefSeq) probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
dmn
Drosophila miranda
Pathway
dmn00010
Glycolysis / Gluconeogenesis
dmn00020
Citrate cycle (TCA cycle)
dmn00620
Pyruvate metabolism
dmn00785
Lipoic acid metabolism
dmn01100
Metabolic pathways
dmn01200
Carbon metabolism
dmn01210
2-Oxocarboxylic acid metabolism
Module
dmn_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dmn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
108160453
00020 Citrate cycle (TCA cycle)
108160453
00620 Pyruvate metabolism
108160453
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
108160453
Enzymes [BR:
dmn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
108160453
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
108160453
NCBI-ProteinID:
XP_017149958
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Position
XL:21489154..21491534
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AA seq
540 aa
AA seq
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MLKKNGGSCLLRLGGVQSPLRQQLLHVWTGEPRSWRRRGGALSISADGRRHKSEDCNSVT
LEHTFKCYDLESGPAMDVELSRDDALKMYSQMLEVRRVETMASNYYKEKKIRGFCHLYIG
QEAVAVGMHARMRKQDSMITAYRCHAWTYLMGVSIYEMMAELLGVRTGCSRGKGGSMHMY
SERYYGGNGIVGAQVPVGAGVALAHQFRRDGGVCIVCYGDGAANQGQVFEAYNIAKLWCL
PCIFVCENNDYAMGTKANRAAANTDFYMRGQYIPGLWVDGNQVLAVRSATQFAIKYALAH
GPIVLEMNTYRYVGHSMSDPGTSYRSRDEVKQMREKRDPITSFRGQIIALCLATEEELKK
IETETRKRVDDDCKKAAKDKEVDPIELHADVYAKNLEPRIRDVHGYHLEHHRISEVCLGK
PKATPQSEIKNVPVGDAAMVAAAAEAKKAADKARAEKAKAEGKEVPKPPGEAPPAAAAGA
PPPAGATAPAAAPPAAAPPPAAAPPAKGAAPPAKGAPPPAKGSAPPAKGAPPPAAPPAKK
NT seq
1623 nt
NT seq
+upstream
nt +downstream
nt
atgctcaagaaaaacggcggcagttgcctgctgcgtttgggcggtgtccagtcaccgctg
cgacagcagcttctccacgtctggacgggtgagccgcgcagctggaggagacgaggagga
gccttgtcaatctcggcagacggcaggcggcacaagtcggaggactgcaatagcgtgacc
ctggagcatacctttaagtgctatgatttggagtcgggccccgccatggatgtggagctg
tcgcgcgatgatgccctgaagatgtacagccagatgctggaggtgaggcgcgttgagacc
atggcctcaaactactacaaggagaagaaaattaggggcttctgtcatttgtatatcggc
caggaggcagtggccgtgggcatgcatgcccgcatgcgcaagcaggactcgatgataacg
gcctaccgctgtcatgcctggacctacctgatgggcgtctccatctatgagatgatggcc
gagctgcttggcgtccgtactggctgcagtcgcggcaagggcggctcgatgcacatgtac
agcgagcggtactacggcggcaatggcattgtgggcgctcaggtgcctgtgggcgccggt
gtggctctggcccatcaattccggcgcgatggcggtgtctgcatcgtatgctatggcgat
ggtgcggccaatcagggccaggtcttcgaggcctacaacattgccaagctgtggtgcttg
ccgtgcatctttgtgtgcgagaacaacgactatgcgatgggcacgaaggcgaatcgggcc
gccgccaacaccgatttctacatgcggggccaatacatacccggcctctgggtggacggc
aatcaggtgctggccgttcgcagtgccacacaatttgccataaagtatgcattggcccat
gggccgattgttctcgagatgaacacctaccgatatgtgggccactctatgtccgatccg
ggcacctcgtatcggtctcgggatgaggtcaagcagatgcgcgagaagcgggatcccata
acgagttttcgcggtcagatcattgccctgtgcctggccaccgaagaggagctgaagaag
atcgagacggagaccaggaaacgtgtggatgacgactgcaagaaggcggccaaggacaag
gaggtggatccgatcgagctgcatgccgatgtctatgccaagaacttggagcccaggata
cgggacgtccatggctaccatctggaacatcatcgtatatcggaggtgtgtctgggcaag
ccaaaagcgactccccaaagcgaaataaagaatgtgcctgtgggggatgcggccatggtg
gctgctgctgccgaggccaagaaggcggccgacaaggccagggcggagaaggctaaggcc
gagggtaaggaggtaccaaaaccaccaggagaagcaccaccagcggcagcagcgggtgct
ccaccaccagcgggtgctacagcaccagctgcagctcccccagcagcagccccaccaccg
gcggctgcaccacctgcaaaaggagccgcaccaccagcaaaaggagctccaccacctgca
aaaggatccgccccacctgcaaaaggagcacctccaccagctgcaccgccggcgaaaaag
taa
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