KEGG   Dasypus novemcinctus (nine-banded armadillo): 101415496
Entry
101415496         CDS       T07872                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X2
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
dnm  Dasypus novemcinctus (nine-banded armadillo)
Pathway
dnm01522  Endocrine resistance
dnm04010  MAPK signaling pathway
dnm04015  Rap1 signaling pathway
dnm04068  FoxO signaling pathway
dnm04071  Sphingolipid signaling pathway
dnm04114  Oocyte meiosis
dnm04148  Efferocytosis
dnm04218  Cellular senescence
dnm04261  Adrenergic signaling in cardiomyocytes
dnm04370  VEGF signaling pathway
dnm04380  Osteoclast differentiation
dnm04550  Signaling pathways regulating pluripotency of stem cells
dnm04611  Platelet activation
dnm04613  Neutrophil extracellular trap formation
dnm04620  Toll-like receptor signaling pathway
dnm04621  NOD-like receptor signaling pathway
dnm04622  RIG-I-like receptor signaling pathway
dnm04625  C-type lectin receptor signaling pathway
dnm04657  IL-17 signaling pathway
dnm04658  Th1 and Th2 cell differentiation
dnm04659  Th17 cell differentiation
dnm04660  T cell receptor signaling pathway
dnm04664  Fc epsilon RI signaling pathway
dnm04668  TNF signaling pathway
dnm04670  Leukocyte transendothelial migration
dnm04714  Thermogenesis
dnm04722  Neurotrophin signaling pathway
dnm04723  Retrograde endocannabinoid signaling
dnm04728  Dopaminergic synapse
dnm04750  Inflammatory mediator regulation of TRP channels
dnm04912  GnRH signaling pathway
dnm04914  Progesterone-mediated oocyte maturation
dnm04917  Prolactin signaling pathway
dnm04926  Relaxin signaling pathway
dnm04932  Non-alcoholic fatty liver disease
dnm04933  AGE-RAGE signaling pathway in diabetic complications
dnm04935  Growth hormone synthesis, secretion and action
dnm04936  Alcoholic liver disease
dnm05014  Amyotrophic lateral sclerosis
dnm05020  Prion disease
dnm05022  Pathways of neurodegeneration - multiple diseases
dnm05132  Salmonella infection
dnm05133  Pertussis
dnm05135  Yersinia infection
dnm05140  Leishmaniasis
dnm05142  Chagas disease
dnm05145  Toxoplasmosis
dnm05152  Tuberculosis
dnm05161  Hepatitis B
dnm05163  Human cytomegalovirus infection
dnm05167  Kaposi sarcoma-associated herpesvirus infection
dnm05169  Epstein-Barr virus infection
dnm05170  Human immunodeficiency virus 1 infection
dnm05171  Coronavirus disease - COVID-19
dnm05205  Proteoglycans in cancer
dnm05208  Chemical carcinogenesis - reactive oxygen species
dnm05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
dnm05415  Diabetic cardiomyopathy
dnm05417  Lipid and atherosclerosis
dnm05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dnm00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101415496 (MAPK12)
   04015 Rap1 signaling pathway
    101415496 (MAPK12)
   04370 VEGF signaling pathway
    101415496 (MAPK12)
   04668 TNF signaling pathway
    101415496 (MAPK12)
   04068 FoxO signaling pathway
    101415496 (MAPK12)
   04071 Sphingolipid signaling pathway
    101415496 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101415496 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    101415496 (MAPK12)
   04218 Cellular senescence
    101415496 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101415496 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101415496 (MAPK12)
   04613 Neutrophil extracellular trap formation
    101415496 (MAPK12)
   04620 Toll-like receptor signaling pathway
    101415496 (MAPK12)
   04621 NOD-like receptor signaling pathway
    101415496 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    101415496 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    101415496 (MAPK12)
   04660 T cell receptor signaling pathway
    101415496 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    101415496 (MAPK12)
   04659 Th17 cell differentiation
    101415496 (MAPK12)
   04657 IL-17 signaling pathway
    101415496 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    101415496 (MAPK12)
   04670 Leukocyte transendothelial migration
    101415496 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101415496 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    101415496 (MAPK12)
   04917 Prolactin signaling pathway
    101415496 (MAPK12)
   04926 Relaxin signaling pathway
    101415496 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    101415496 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101415496 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    101415496 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    101415496 (MAPK12)
   04722 Neurotrophin signaling pathway
    101415496 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101415496 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101415496 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    101415496 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101415496 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    101415496 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101415496 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101415496 (MAPK12)
   05161 Hepatitis B
    101415496 (MAPK12)
   05171 Coronavirus disease - COVID-19
    101415496 (MAPK12)
   05163 Human cytomegalovirus infection
    101415496 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101415496 (MAPK12)
   05169 Epstein-Barr virus infection
    101415496 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101415496 (MAPK12)
   05135 Yersinia infection
    101415496 (MAPK12)
   05133 Pertussis
    101415496 (MAPK12)
   05152 Tuberculosis
    101415496 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101415496 (MAPK12)
   05140 Leishmaniasis
    101415496 (MAPK12)
   05142 Chagas disease
    101415496 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101415496 (MAPK12)
   05020 Prion disease
    101415496 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    101415496 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101415496 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    101415496 (MAPK12)
   05415 Diabetic cardiomyopathy
    101415496 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101415496 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    101415496 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101415496 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101415496 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dnm01001]
    101415496 (MAPK12)
Enzymes [BR:dnm01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101415496 (MAPK12)
Protein kinases [BR:dnm01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101415496 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kinase-like Kdo
Other DBs
NCBI-GeneID: 101415496
NCBI-ProteinID: XP_004453271
Ensembl: ENSDNOG00000036402
LinkDB
Position
Unknown
AA seq 238 aa
MPFMGTDLGKLMKHEKLSEDRVQFLVYQILKGLQYIHAAGVIHRDLKPGNLAVNEDCELK
ILDFGLARQADSEMTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMITGQTLFKG
SDHLDQLKEIMKVTGTPPAEFVQRLQSADAKNYMKGLPELEKKDFASILTNASPLAVNLL
EKMLVLDAEQRVTAAEALTHPYFEALHDTEEEPRAQKYDDSLDDVDRTLDGWKQGFCQ
NT seq 717 nt   +upstreamnt  +downstreamnt
atgccgttcatgggcaccgacctgggcaagctcatgaagcacgagaagctgagcgaggac
agggtccagttcctggtgtaccagatcctgaaggggctccagtacatccacgccgcgggc
gtcatccacagggacctgaagccgggcaacctggccgtgaacgaggactgtgagctgaag
atcttggacttcggcctcgcccgtcaggcggacagtgagatgacggggtacgtggtgacc
cgatggtaccgggcgcccgaggtcattctgagctggatgcactacacgcagacagtggac
atctggtccgtgggctgcatcatggcagagatgatcaccgggcagacgctgttcaagggc
agtgaccatctggaccagctgaaggagatcatgaaggtgacggggacgccgccggccgag
tttgtgcagaggctgcagagcgcagatgccaagaactacatgaagggcctccccgagttg
gagaagaaggattttgcgtccatcctgaccaatgcaagccctctggccgtgaacctcctg
gagaagatgctggtgctggacgcggagcagcgggtgacggcggccgaggcgctgacccac
ccttacttcgaggccctgcacgacacggaggaggagcccagggcccagaagtacgacgac
tccttggacgacgtggaccgcaccctggatggctggaagcaaggtttctgccagtga

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