Dipodomys ordii (Ord's kangaroo rat): 105993301
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Entry
105993301 CDS
T07834
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
dord
Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord00010
Glycolysis / Gluconeogenesis
dord00020
Citrate cycle (TCA cycle)
dord00620
Pyruvate metabolism
dord00785
Lipoic acid metabolism
dord01100
Metabolic pathways
dord01200
Carbon metabolism
dord01210
2-Oxocarboxylic acid metabolism
dord04066
HIF-1 signaling pathway
dord04922
Glucagon signaling pathway
dord05230
Central carbon metabolism in cancer
dord05415
Diabetic cardiomyopathy
Module
dord_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dord00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
105993301 (Pdha1)
00020 Citrate cycle (TCA cycle)
105993301 (Pdha1)
00620 Pyruvate metabolism
105993301 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
105993301 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
105993301 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105993301 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
105993301 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
105993301 (Pdha1)
Enzymes [BR:
dord01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
105993301 (Pdha1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
105993301
NCBI-ProteinID:
XP_012881956
Ensembl:
ENSDORG00000011848
UniProt:
A0A1S3FZI1
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLLGVAQKPATRVLVASRNFANDATFEIKKCDLHRLDEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgccgccgtctcccgcgtgttgttgggcgttgcccagaagccggca
accagagttctagtggcatcgcgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgaccttcaccgactggatgaaggccctcccgttacaactgtgctcaccagagaggat
gggctcaaatactataggatgatgcagactgtgcgcagaatggagttaaaagctgatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgc
tgtgtggggctggaggctggcataaaccccacagaccatctcatcacagcctaccgggct
catggcttcaccttcactcggggtctttctgttcgtgaaattctcgcagagctaacagga
cgaagaggaggttgtgctaaagggaaaggaggatctatgcacatgtatgccaagaacttc
tacgggggcaatggcatcgttggagctcaggtacccctgggagctgggattgctctggcc
tgtaagtataatggaaaagatgaagtctgtttgacactatatggtgatggtgctgctaat
cagggtcagatatttgaagcttacaatatggcagcattgtggaaattaccatgcattttc
atctgtgagaataaccgctatggaatgggaacgtctgttgagagagcagcagccagtact
gattactacaagagaggagactttatccctgggctgagggtagatggaatggatatcttg
tgtgtccgagaggccacgaagtttgcagctgcctattgtagatctgggaagggacctatc
ctgatggagctgcagacttaccgttaccatggacacagcatgagtgaccctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaatagcaatctggccagtgttgaagaattgaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgctgcccagtttgccacagctgatcctgagccacca
ttggaagagctcggctatcacatctacagcagcgatccaccatttgaagtgcgtggtgcc
aaccagtggatcaagtttaagtcagtcagttaa
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