Dipodomys ordii (Ord's kangaroo rat): 105995863
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Entry
105995863 CDS
T07834
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
dord
Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord00010
Glycolysis / Gluconeogenesis
dord00020
Citrate cycle (TCA cycle)
dord00620
Pyruvate metabolism
dord00785
Lipoic acid metabolism
dord01100
Metabolic pathways
dord01200
Carbon metabolism
dord01210
2-Oxocarboxylic acid metabolism
dord04066
HIF-1 signaling pathway
dord04922
Glucagon signaling pathway
dord05230
Central carbon metabolism in cancer
dord05415
Diabetic cardiomyopathy
Module
dord_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dord00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
105995863
00020 Citrate cycle (TCA cycle)
105995863
00620 Pyruvate metabolism
105995863
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
105995863
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
105995863
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105995863
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
105995863
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
105995863
Enzymes [BR:
dord01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
105995863
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Paralog
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
105995863
NCBI-ProteinID:
XP_012885198
UniProt:
A0A1S3G8P4
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MKKMLASVVSRVLGATQKPPLRVLLTSCNYSKDATIDIKSCDLYRLEGGPASSTLLTRDD
GLKYYRAMQIVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGIEAAIKPTDNVITSYRA
HGICYTRGLSVKSILAELTGRRGGCAKGKGGSMHMYAKHFFGGNGIVGAQVPLGAGIALA
CKYLGKRDICLAMYGDGAANQGQIAEAYNMAALWKLPCVFICENNRYAMGTAVERAAAST
DYYKRGNFIPGLKVNGMDVLCVREATRFAADHCRAGKGPIVMELQTYRYHGHSMSDPGVS
YRTREEIQTMRSKSDPIMLLQEKMISHKLSSVEELKEIDVEVRKEIEEAAQFATTDPEPS
LDELGHHLYHSNPPFDVRGANQWIKYKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaagatgctggcttctgtggtctcccgcgtgttgggggccacccagaagccccct
ctcagagtactgctgacctcctgcaactattccaaggatgctaccattgacattaagagc
tgcgatctttaccggctggaggggggccccgcgtcctccaccttgctaacccgggacgac
gggctcaagtactaccgggccatgcagatcgttcgccggatggaactgaaggcggaccag
ctctacaaacagaaatttatccgtggcttctgccacctgtgcgacggccaggaagcttgc
tgcgtggggatcgaggcggccatcaagcccacggataacgtgatcacctcctaccgggcg
catggcatctgctacacgcgcggactctcggtcaagtcgatcctggcggagctgacgggg
cgcaggggaggatgcgccaaaggcaagggcggctccatgcacatgtacgccaagcacttc
ttcgggggcaacggcatcgtgggcgcgcaggtgcccctgggcgcggggatcgccctggcc
tgcaagtacctggggaaacgggacatctgcctggccatgtatggcgacggagctgccaac
cagggccagatcgccgaggcctacaacatggcagcgctgtggaagctgccgtgcgtgttt
atctgcgagaacaaccgctacgccatgggcacggcggtggagagggcggcggccagcacc
gattactacaagcggggcaacttcatcccgggcctcaaggtgaacggcatggatgtgctg
tgcgtgcgcgaggccaccaggttcgcggcggatcactgccgggccgggaagggccccatc
gtgatggagctgcagacctaccggtaccacgggcacagcatgagcgacccgggcgtgagc
taccgcacacgcgaggagatccagaccatgaggagcaagagcgaccccatcatgctgctc
caggagaagatgatcagccacaagctcagcagcgtggaggagctcaaggagatcgatgtg
gaggtgaggaaggagatcgaggaggccgcccagttcgccaccaccgaccccgagcccagc
ctggatgagctgggccatcacctctaccacagcaacccgcccttcgacgttcggggggcc
aaccagtggatcaagtacaaatccatcagttaa
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