Danio rerio (zebrafish): 352943 Help Entry 352943            CDS       T01004                                  Symbol tph1a Name (RefSeq) tryptophan 5-hydroxylase 1a   KO K00502   tryptophan 5-monooxygenase [EC:1.14.16.4] Organism dre  Danio rerio (zebrafish) Pathway dre00380   Tryptophan metabolism dre00790   Folate biosynthesis dre01100   Metabolic pathways Module dre_M00037   Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin Brite KEGG Orthology (KO) [BR:dre00001]  09100 Metabolism   09105 Amino acid metabolism    00380 Tryptophan metabolism     352943 (tph1a)   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     352943 (tph1a) Enzymes [BR:dre01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor     1.14.16.4  tryptophan 5-monooxygenase      352943 (tph1a) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Biopterin_H ACT TH_ACT DUF262 ACT_4 Motif Other DBs NCBI-GeneID:  352943 NCBI-ProteinID:  NP_840091 ZFIN:  ZDB-GENE-030317-1 Ensembl:  ENSDARG00000029432 UniProt:  Q6PBX4 LinkDB All DBs Position 25:complement(8139220..8160012) Genome browser AA seq 483 aa AA seqDB search MYSSKSDGPRRGRSFDSMNLGMTLEEKQLNNEMNKSAFTKIEENKDNKTESSETGRAAVV FSLKNEVGGLVKALKLFQENHVNLVHIESRKSKRRNSEFEIFVDCDSNREQLHEIIQLLR KHVNVVEMDAPDNRLPEESEMENVPWFPKKISDLDKCANRVLMYGSDLDADHPGFKDNVY RKRRKYFADLAMSYKHGDPIPRIEFTEEEVKTWGVVFRELNKLYPSHACREYLKNLPLLI KHCDSREDNIPQLEDVSRFLKERTGFTIRPVAGYLSPRDFLAGLAFRVFHCTQYVRHSSD PLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASDDSIQKLATCYFFTVEFGLC KQEGKLRAYGAGLLSSISELKHALSGNARILPFDPNVTCKQECIITTFQDVYFMSDSFEE AKVKMREFAKTIKRPFSVRYNPYTQSVDVLKDTTSINNVVEELRHELDIIGDALSRLNKQ LGV NT seq 1452 nt NT seq  +upstreamnt  +downstreamnt atgtactcgagtaaaagcgacgggccacgcagaggaagatcttttgattccatgaacctc ggaatgactttggaggagaagcagcttaataatgaaatgaacaaatctgctttcacgaag atcgaggagaataaagacaacaaaacagagtcttcagagacaggccgggctgcggttgtg ttttccctgaaaaatgaagtcggtgggctagtcaaggctttaaagcttttccaggaaaac catgtaaaccttgtacacattgagtcccggaaatctaaaaggcgcaactcagagtttgaa atctttgtggactgcgacagcaaccgtgaacaactgcacgagatcattcagctgctgagg aaacatgttaacgtggtggagatggacgcgcctgacaaccgcctgcctgaggaaagcgag atggagaatgtgccgtggttcccgaagaagatttcagatctggataaatgtgcgaaccgc gtgctgatgtatggatcagatctagatgcagatcatcctggattcaaggacaatgtctat cgcaaaaggagaaagtactttgcagacttggctatgagctacaaacatggagatcccatc cctcgcattgagttcaccgaggaggaggtgaagacgtggggtgtcgtgttcagagagctg aataaactctatccctcacacgcctgccgagagtacctgaagaacctgccgctgctcatc aaacactgcgactcccgtgaagacaacatccctcagctggaggacgtctcacgctttctc aaagagagaacaggcttcaccatcaggcctgtggcaggatatttgtctcctcgagacttt ctggcaggattggctttccgtgtgtttcactgcactcagtatgtcaggcacagttcagac ccgctctacacacctgagccagacacatgtcatgagctgctcggacacgttcctcttctg gcggagcccagttttgctcagttcagtcaggagattggtctggcttcactgggagcatca gacgactccatacaaaaactcgccacatgttatttcttcactgtggagttcgggctctgt aagcaggaagggaaactgagagcttatggagcaggtctgctgtcctctatcagcgagctg aagcacgcactgtcaggaaatgccaggatcttgccttttgaccccaatgtgacttgcaaa caggagtgcatcatcaccacgtttcaggacgtttacttcatgtcagactcctttgaggaa gcgaaagtcaaaatgagggagtttgcaaagaccatcaagcggccattttcagtgcgttat aacccgtacacgcagagtgtggacgttttgaaagacacgaccagcatcaacaatgtggtg gaagaactgagacatgagctggacatcattggagatgcattaagcaggctaaacaaacaa ctaggagtctga

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