Danio rerio (zebrafish): 64815
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Entry
64815 CDS
T01004
Symbol
hsd17b8
Name
(RefSeq) estradiol 17-beta-dehydrogenase 8
KO
K13370
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:
1.1.1.62
1.1.1.239
]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre00061
Fatty acid biosynthesis
dre00140
Steroid hormone biosynthesis
dre01100
Metabolic pathways
dre01212
Fatty acid metabolism
Module
dre_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
64815 (hsd17b8)
00140 Steroid hormone biosynthesis
64815 (hsd17b8)
Enzymes [BR:
dre01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
64815 (hsd17b8)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
64815 (hsd17b8)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
adh_short_C2
adh_short
KR
Epimerase
Polysacc_synt_2
3Beta_HSD
Sacchrp_dh_NADP
GDP_Man_Dehyd
RmlD_sub_bind
3HCDH_N
TrkA_N
Motif
Other DBs
NCBI-GeneID:
64815
NCBI-ProteinID:
NP_001005292
ZFIN:
ZDB-GENE-010110-1
Ensembl:
ENSDARG00000001169
UniProt:
Q561S1
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Position
19:7173871..7179691
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AA seq
256 aa
AA seq
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MAASTRLISRLTLVTGGGSGIGRAVCQRFATEGASVVVADRNEESANQTLELLPREHRGQ
EHMALGVDVSSKDSVEKLVTSIQRRYFQPPSVCVNAAGITQDEFILKMEEDDFDKVIKVN
LKGTFLVTQAVSKALVSAGSAKGSIITVGSIVGKVGNIGQVNYASSKAGVQGLTRTAAKE
LSKFGIRCNCVLPGFITTPMTDKVPEKVIDKITSIIPLGRMGEPAEVADACAFLASDDSR
YITGVSIEVAGGLFIG
NT seq
771 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgtccactcgactcatatccaggttgacgttagtcacgggaggtggcagtggc
atcggcagggcagtctgtcagagattcgccactgaaggtgcttctgtagtagttgctgac
cgcaatgaggaatcagccaatcagacgctggaactgctgccacgtgagcacagaggtcaa
gagcacatggcccttggggtggacgtgtcttcaaaggacagtgtggagaagctggtgacc
agcatacagcgccgctacttccagcctccatcagtgtgcgtgaacgcagccggcatcact
caggatgagttcatcctcaagatggaggaagacgactttgacaaagttattaaagtcaat
cttaagggcacatttctggtgactcaggcagtctcaaaggctttagtctctgcagggtca
gcgaagggctccataattacagtgggcagtatcgtgggcaaggttggaaatattggccag
gtgaattacgcctcttctaaagcaggagtacagggactcactcgcaccgcagccaaagag
ctgagcaagtttggtattcgctgtaactgtgtgctgccggggttcatcactacacccatg
actgataaagtcccagagaaagtcattgataaaatcacatctattattccactgggaaga
atgggagagcctgctgaagtagctgacgcctgtgcgtttctggcttctgatgacagccga
tatatcaccggagtcagcattgaagttgccggcggactcttcattggctga
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integrated database retrieval system
