Danio rerio (zebrafish): 791145
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Entry
791145 CDS
T01004
Symbol
pde8a
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre00230
Purine metabolism
dre01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
791145 (pde8a)
Enzymes [BR:
dre01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
791145 (pde8a)
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Motif
Pfam:
PDEase_I
PAS
PDE8
PAS_9
Response_reg
PAS_3
PAS_4
Motif
Other DBs
NCBI-GeneID:
791145
NCBI-ProteinID:
NP_001074096
ZFIN:
ZDB-GENE-070112-622
Ensembl:
ENSDARG00000087941
UniProt:
A1L1W3
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Position
18:complement(16378..33817)
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AA seq
817 aa
AA seq
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MGCASSIHISDRVVYHSGKESEEPPHTHSHTHTCTPDTGDRSSAGGQGSLTELQFGPMKL
NEDQLQVLLVFARDDAQSSSFISACERCGFGCSVCRTPEAALECVLQKSPDLIIIDHRHP
RGLDGEALCRSIRAVSCSHNTVIVAVVKRPDREEATVMPLISAGFNRRFVENSSMMSCYN
ELLQLHHGEIRAQIKLRACNALFTALEQSQEAIEISSEDHIIQYVNPAYECMMGYQCGEL
LKENTEVPKSERNRPDLLDNISSCMLRGKEWQGVYYAKKKNGDSVQQNVRMTPVIGQGGK
VRHCVSVNRPLNDHNKTEKSCERVQAESQTDIPQSSKHKDRRKGSLDVRSTTSRGSDGSS
QRRHSSMARIHSMTIEAPITKVINIINAAQESSPLPVAEALDRVLEILRSSELYSPQLAT
KEEDPHTNDLVGGLMTDGLRRLSGNEYIFTTKQLHHMTSHQTTPLSLNDIPQCIAQTMEN
EDSWDFDIFNLESATLKRPLAFLGLKLFSRFGVCEFLGCAEATLRSWLQNIEASYHGSNP
YHNSTHAADVLHATAYFLCKERVKQSLDPIDEVAALIAAAVHDVDHPGRTNSFLCNAGSE
LAVLYNDTAVLESHHAALAFQITTRDDKSNIFRNMERNEYRTLRQAIIDMVLATEMTKHF
EHVNKFVNSINKPLAALEENGGSDDEDSVKSVLTSPENRILVKRMLIKCADISNPCRPLE
LCIEWAGRISEEYFAQTDEEKQRGLPVVMPVFDRHTCSIPKSQISFIDYFITDMFDAWDA
FADLPNLMQHLDNNFKYWKSLDEQKLRSLRAPPEEHA
NT seq
2454 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcctccagcatccacatctccgaccgggtggtgtatcacagcgggaaagag
tccgaggagccgccgcacacacactcacacacacacacctgcacaccggataccggagac
cgcagcagcgccggcggacagggctcgctaacggagctgcagtttggaccaatgaagctg
aatgaagatcagctgcaggtgctgctggtgtttgcgcgtgatgacgctcagagcagcagc
ttcatcagtgcgtgtgagcgctgtggtttcggctgcagtgtgtgtcgaacaccagaggcg
gcgctggagtgtgtcctgcagaagagccccgacctgatcattattgaccaccggcacccc
cgagggctggacggagaggcgctctgccgctcaatccgggccgtcagctgctctcacaac
actgtgatcgtggctgtagtcaaaaggccggatcgtgaagaagccactgtgatgccgctg
atatcagcagggttcaacaggagattcgtggagaactccagcatgatgtcctgctataat
gagctcctgcagcttcaccatggagagatccgagcacagatcaaactcagagcctgtaat
gctttgtttactgcgctggaacagagtcaggaagctattgagatcagcagtgaagatcac
atcatacagtacgtcaatccagcgtacgagtgcatgatgggataccagtgcggggagctg
ctgaaggagaacactgaagtgcctaagagtgagagaaacagaccagacctgctggacaac
atcagctcctgcatgctgcgggggaaggagtggcagggggtttattatgccaaaaagaag
aacggggacagtgtgcagcagaacgtgaggatgacacctgtcattggacagggaggtaaa
gtcagacactgtgtgtctgttaacaggcctttaaatgaccataataagacagagaaatcc
tgcgagcgtgtccaggctgaatcacagacagatatcccgcaatccagcaaacacaaggac
cgcaggaaaggatcgctggacgttcgctcgacaacctccagaggcagtgatggaagttct
cagaggagacactcgtctatggccagaatacactccatgaccatagaggcgcccatcact
aaggtgatcaacatcatcaatgcggcgcaggagagcagtccgctgccggtggctgaggct
ctggatcgggtgctggagatcctgcgcagctctgagctctactcgcctcagctcgccacc
aaggaggaggacccgcatactaatgacctggtgggcgggctgatgacggacggcctgcgc
aggttatctgggaacgagtacatcttcaccactaaacagctgcatcacatgaccagtcac
cagaccacgcccctgtccctcaacgacatcccacaatgcatcgctcagaccatggagaac
gaggactcatgggacttcgacatattcaacctggaatcagccaccttgaagaggccgctg
gcgttcctgggcctgaagctgttctcccggttcggtgtgtgtgagtttctgggctgtgcg
gaggcgacgctgcgctcatggctgcagaacatcgaggctagttaccatggcagcaaccca
taccacaactccacacacgccgcagacgtgctgcacgccaccgcctacttcctgtgcaag
gagcgcgtcaagcaaagtctggaccccatagacgaggtcgcggctctgatcgctgctgct
gttcatgacgtggatcatcccggacgcacaaactccttcctgtgcaacgcaggaagtgag
ctggcggtgctgtacaacgacacggcggtgctggagagtcaccacgccgcgctcgccttc
cagatcaccacacgagacgacaagagcaacatcttcaggaacatggagaggaatgagtac
cgcacgctccgtcaggccatcattgatatggttctggccactgagatgaccaaacacttc
gagcacgtcaacaagttcgtcaacagcatcaacaaaccactggcagcgctggaggagaac
gggggcagtgatgatgaggactcggtgaagagcgtcctgacgtctccagagaatcgtatc
ctggtgaagcgcatgttgatcaagtgtgccgacatctccaacccctgcagacccctggag
ctgtgcatcgagtgggccggacgcatctctgaggagtacttcgctcagacggacgaggag
aagcagcggggtctgccggtggtgatgccggtgtttgatcgtcacacctgcagcattccc
aaatcccagatctccttcatcgactacttcatcaccgacatgttcgacgcctgggacgcg
ttcgccgatctgcccaatctgatgcagcatctggacaataacttcaagtactggaagtct
ctggacgagcagaagctgcggagtctgagagcgccgccggaggaacacgcgtga
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