Desmodus rotundus (common vampire bat): 112300586 Help Entry 112300586         CDS       T05907                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism dro  Desmodus rotundus (common vampire bat) Pathway dro00230   Purine metabolism dro01100   Metabolic pathways dro01522   Endocrine resistance dro04015   Rap1 signaling pathway dro04020   Calcium signaling pathway dro04022   cGMP-PKG signaling pathway dro04024   cAMP signaling pathway dro04062   Chemokine signaling pathway dro04072   Phospholipase D signaling pathway dro04114   Oocyte meiosis dro04211   Longevity regulating pathway dro04213   Longevity regulating pathway - multiple species dro04261   Adrenergic signaling in cardiomyocytes dro04270   Vascular smooth muscle contraction dro04371   Apelin signaling pathway dro04540   Gap junction dro04611   Platelet activation dro04713   Circadian entrainment dro04714   Thermogenesis dro04723   Retrograde endocannabinoid signaling dro04724   Glutamatergic synapse dro04725   Cholinergic synapse dro04727   GABAergic synapse dro04742   Taste transduction dro04750   Inflammatory mediator regulation of TRP channels dro04911   Insulin secretion dro04912   GnRH signaling pathway dro04913   Ovarian steroidogenesis dro04914   Progesterone-mediated oocyte maturation dro04915   Estrogen signaling pathway dro04916   Melanogenesis dro04918   Thyroid hormone synthesis dro04921   Oxytocin signaling pathway dro04923   Regulation of lipolysis in adipocytes dro04925   Aldosterone synthesis and secretion dro04926   Relaxin signaling pathway dro04927   Cortisol synthesis and secretion dro04928   Parathyroid hormone synthesis, secretion and action dro04934   Cushing syndrome dro04935   Growth hormone synthesis, secretion and action dro04970   Salivary secretion dro04971   Gastric acid secretion dro04972   Pancreatic secretion dro04976   Bile secretion dro05032   Morphine addiction dro05163   Human cytomegalovirus infection dro05166   Human T-cell leukemia virus 1 infection dro05200   Pathways in cancer dro05207   Chemical carcinogenesis - receptor activation dro05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:dro00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     112300586 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     112300586 (ADCY4)    04371 Apelin signaling pathway     112300586 (ADCY4)    04020 Calcium signaling pathway     112300586 (ADCY4)    04072 Phospholipase D signaling pathway     112300586 (ADCY4)    04024 cAMP signaling pathway     112300586 (ADCY4)    04022 cGMP-PKG signaling pathway     112300586 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     112300586 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     112300586 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     112300586 (ADCY4)    04062 Chemokine signaling pathway     112300586 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     112300586 (ADCY4)    04923 Regulation of lipolysis in adipocytes     112300586 (ADCY4)    04912 GnRH signaling pathway     112300586 (ADCY4)    04913 Ovarian steroidogenesis     112300586 (ADCY4)    04915 Estrogen signaling pathway     112300586 (ADCY4)    04914 Progesterone-mediated oocyte maturation     112300586 (ADCY4)    04921 Oxytocin signaling pathway     112300586 (ADCY4)    04926 Relaxin signaling pathway     112300586 (ADCY4)    04935 Growth hormone synthesis, secretion and action     112300586 (ADCY4)    04918 Thyroid hormone synthesis     112300586 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     112300586 (ADCY4)    04916 Melanogenesis     112300586 (ADCY4)    04925 Aldosterone synthesis and secretion     112300586 (ADCY4)    04927 Cortisol synthesis and secretion     112300586 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     112300586 (ADCY4)    04270 Vascular smooth muscle contraction     112300586 (ADCY4)   09154 Digestive system    04970 Salivary secretion     112300586 (ADCY4)    04971 Gastric acid secretion     112300586 (ADCY4)    04972 Pancreatic secretion     112300586 (ADCY4)    04976 Bile secretion     112300586 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     112300586 (ADCY4)    04727 GABAergic synapse     112300586 (ADCY4)    04725 Cholinergic synapse     112300586 (ADCY4)    04723 Retrograde endocannabinoid signaling     112300586 (ADCY4)   09157 Sensory system    04742 Taste transduction     112300586 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     112300586 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     112300586 (ADCY4)    04213 Longevity regulating pathway - multiple species     112300586 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     112300586 (ADCY4)    04714 Thermogenesis     112300586 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112300586 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     112300586 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     112300586 (ADCY4)    05163 Human cytomegalovirus infection     112300586 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     112300586 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     112300586 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     112300586 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     112300586 (ADCY4) Enzymes [BR:dro01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      112300586 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N DUF3180 CD52 Motif Other DBs NCBI-GeneID:  112300586 NCBI-ProteinID:  XP_024411629 LinkDB All DBs Position Unknown AA seq 1077 aa AA seqDB search MARLFSTRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLCALLALLVVASASGRDLTSDPG FLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWAALLALGQGFLFTGGLVSAWDQV SFFLFVIFTTYAMLPLGMKEATAAGLVSSLSHLLVLGLYLGPQLDSRPALLPQLAANTVL FLCGNVAGVYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQAGQGSRPENTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDVNMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEASGVPGRVHITGATLALLAG AYAVEDAAMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR YLESWGAAKPFAHLSHVESPVSTSTPLQEKALASFSPQWSLDRSRTPWGLDDELDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFKYYAACTFLVFLSNFI IQMLVTNRTPALAITYSITFLLFLLLLFICFSEHLTRCVLKGPKMLHWLPALSGLVATRP GLRVALGTATILLIFAMAIASLFFIPATSNCPFRAPNVSSMAFNLSWELPGSLPLISIPY SMHCCVLGFLSCSLFLHMSFELKLLLLLLWLAASCSLFLHSHAWLSDCLVARLYQGSLDS RPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRL LLENVLPAHVAPKFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQEAQQDAERSCSHLGTMV EFAVALGCKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETAWALQALGYTCYSRGVIKVKGKGQLCTYFLNTDLTRAGPPSATLG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggccagactcttcagtacccggccgccgcccagcgaagacctcttctacgagacctac tacagcctgagccagcagtacccgctcctgctactgctgctggtgatcgtgctctgcgcg ctcctggccctgcttgtcgttgcctcagccagcggcagggatttgacctcagacccaggc ttcctgaccacggtgctgtgcgcgctgggtggcttctctctgctactgggcctagcctcc cgcgagcagcgactgcagcgctggacgcgtcccctgtcgggcctcgtgtgggcagcgctg ctcgcgctgggccaaggtttcctgttcactgggggcctggtgagcgcctgggaccaggtg tcctttttcctctttgtcatcttcactacctacgccatgttgcctttgggcatgaaagaa gccaccgctgcgggtcttgtctcgtcgctctcacacctgctggtcctcgggctgtatctt gggcctcagctggactcaagacccgcgctgctgccgcagctggcagcaaacacggtgttg ttcctgtgcgggaatgtggccggagtgtaccacaaggcgttgatggagcgggcactgcgc gccaccttcagagaggcgcttagttccctgcactctcgccggcggctggacacagagaag aagcaccaggaacaccttctcttgtccatccttcctgcctacttggcccgagagatgaag gcagagatcatggcacggctgcaggctggacaggggtcaaggccagagaacaccaacaac ttccacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg ggcttcacgcggctagccagtgagtgctccccaaaggagttggtgctgatgctcaatgag ctctttggcaagttcgaccagatcgccaaggagcacgaatgcatgcggatcaagatcctg ggagactgttactactgtgtctccgggctgcccctctccctgccagaccacgccatcaac tgcgtgcgcatggggctggacatgtgccgggccatcaggaaactgcgagcagccaccggt gtggacgtcaacatgcgtgtgggcgtgcactcaggaagtgtgctctgtggagtcatcggg ctgcagaagtggcagtatgatgtctggtcccatgatgtcacattagccaaccacatggag gcgagtggtgtgccaggacgagtgcacatcacaggggctactctggccctgctggcagga gcttacgctgtggaggatgcagccatggaacaccgggatccatacctgcgggagctaggg gagcctacctacctggtcattgacccccgggctgaggaggaggatgagaagggcactgca ggagggttgctgtcctctctcgagggccccaagatgcgtccatcactgctaatgacccgc tacctggaatcctggggtgcagccaagccttttgcccacctgagccacgttgagagccct gtgtccacttctactcctctccaggagaaggccctggcttccttcagcccccagtggagc ctggaccggagccgtacaccctggggactagatgatgaactggacactggagatgccaag ttcttccaggtcatcgaacagctcaactctcagaaacagtggaagcagtcaaaggacttc aacccgctgacactgtacttccgagagaaggaaatggagaaagagtatcgactctctgca ctccctgccttcaaatactatgcagcctgcaccttcctggtttttctctccaacttcatc atccagatgctggtgacaaacaggaccccggcgctggccatcacctatagcatcaccttc ctcctcttcctcctcctcctcttcatctgcttctcagagcacctgacgaggtgtgtcttg aaaggccccaaaatgctgcactggctgcccgcactgtctggcctggtggccacccggccc ggactgagagttgccctgggcactgccaccatcctcctcatctttgccatggccattgcc agcctgttcttcataccagcaacatcgaactgccctttcagggctcccaatgtgtcctcc atggctttcaacctctcctgggagctccctgggtccctgcctctcatcagcattccatac tccatgcactgctgtgtgctgggtttcctctcctgctccctctttctgcacatgagcttc gaactgaagctgctgctgctcctgctatggctggcggcctcctgctccctcttcctgcac tcccatgcctggctgtctgactgcctcgtcgcccgcctctatcagggctccttggactcc aggcctggagtgctgaaggagccaaaattgatgggagctatctccttcttcatcttcttc ttcacactccttgtcttggctcggcagaatgagtactactgccgcctggatttcctgtgg aagaagaagctgaggcaggagagggaggagacagagacaatggagaatttgactcggctg ctcttggagaatgtgctccctgcacacgtggcccccaagtttattggccagaaccggcgc aatgaggacctctaccaccagtcctacgaatgtgtctgtgtcctcttcgcctcagtccca gacttcaaggagttttactctgagtccaacatcaaccacgaggggctagagtgtctgcgg ctgctcaatgagatcattgctgattttgatgagctgctctctaagcccaagttcagtggg gtggagaagatcaaaaccatcggcagcacctacatggcagctacaggcctaaatgccacc tctggacaggaggcacagcaggatgctgagcgaagctgtagccaccttggcaccatggtg gaatttgcagtggcccttgggtgtaagctggacgttatcaacaagcactcattcaacaac ttccgcttgcgtgtggggttgaaccatggacctgtagtggccggagtgataggggcccag aaaccacaatatgacatctggggcaacacggtgaacgtggccagccgcatggagagtaca ggagtcctgggcaagatccaagtgacggaggagacggcctgggccctgcaggccttaggc tacacctgctacagcagaggtgttatcaaggtcaaaggcaaagggcagctgtgcacctac ttcctgaacacagatttgacacgagctggacctccctcagccaccctaggctga

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