Desmodus rotundus (common vampire bat): 112310890
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Entry
112310890 CDS
T05907
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro00061
Fatty acid biosynthesis
dro00620
Pyruvate metabolism
dro00640
Propanoate metabolism
dro01100
Metabolic pathways
dro04152
AMPK signaling pathway
dro04910
Insulin signaling pathway
dro04920
Adipocytokine signaling pathway
dro04922
Glucagon signaling pathway
dro04931
Insulin resistance
dro04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
112310890 (ACACB)
00640 Propanoate metabolism
112310890 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
112310890 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
112310890 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
112310890 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
112310890 (ACACB)
04922 Glucagon signaling pathway
112310890 (ACACB)
04920 Adipocytokine signaling pathway
112310890 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
112310890 (ACACB)
04931 Insulin resistance
112310890 (ACACB)
Enzymes [BR:
dro01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
112310890 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
112310890 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
112310890 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
112310890
NCBI-ProteinID:
XP_024422984
LinkDB
All DBs
Position
Unknown
AA seq
2459 aa
AA seq
DB search
MILLFFLSCLIVSCLTLSWLKIWGKMTDSTPATKNHSEGDILLNQESLPASDSSEEPLQK
NGDSSSGPKTPDQAEPASLKGRKDASLKRTSRPPPYRNPQKSPLPSRDASPANGTGTRSP
EAPDTNVLSSPTRPQARGRALSREDQKQAHIKSQLMTKFILGSFDDNSSDEDASVGSRES
SRRGSRASLGGLPLEAARTAGDSESSVPTMRPSMSGLHLVRRGREQKKVSLHRDFTVASP
AEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKAN
AEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKH
EIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLSWSGSGLTVELAEDDLQQGTRVCVPED
IYHQGCVKDVEEGLEAAERIGFPLMIKASEGGGGKGIRKVESAEDFPILFRQVQSEIPGS
PVFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPAVFEFM
EQCAVRLAKTVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMIADVNLPAAQLQI
AMGVPLHRLKDIRLLYGESPWGMTPISFDAPSNPPIPRGHVIAARITSENPDEGFKPSSG
TVQELNFRSSKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR
GDFRTTVEYLINLLETESFQNNDIDTGWLDHLIAEKVQAEKPDIMLGVVCGALNVADAMF
RTCMTDFLHSLERGQVLPAASLRNTVDVELIYGGFKYILKVARQSLTMFVLIMNGCHIEI
DAHRLNDGGLLLSYGGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRAPSAGKLTQ
YTVEDGGYVEAGGSYAEIEVMKMIMSLNVQESGRVKYIKRPGAVLEAGCVVARLELDDPS
KVHPARPFTGELPHQPTLPIMGEKLNQVFHSALENLMNVMNGYCLPEPVFTIKLKEWVQK
LMMTLRHPSLPLLELQEIMTSVSGRIPAPVEKLVRRVMAQYASNITSVLCQFPSQQIATI
LDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLKRYLQVEHHFQQA
HYDKCVINLREQLKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEELTSILN
ELTQLNKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDRYGHQFCPENLKKLI
LSETTIFDVLPTFFYHTNEVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFML
PSSHPNRMAVPISDTNPDLLRHSTELFMDSGFSPLSQRMGAMVAFRRFEEFTRNFDEVIS
CFANVAEDTPLFRKAQTSMYCEEDGKNLREEPIHILNVAIQYADHLEDEELVPILRTFVQ
SKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRN
FDLTAVPCANHKMHLYLGAARVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGER
LLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPYKIEESVRPMVMRYGSRLWKLRV
LQAEVKINIRETTSGSAIPIRLFITNESGYYLDISLYKEVTDPRSGNIMFHGFGNKQGPQ
HGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPELFRQALFKMWGSPDKYPKDILTYTE
LVLDPQGQLVEMNRLPGGNEVGMVAFKMRFKTREYPEGRDAIVISNDITFRIGSFGMGED
LLYLRASEMARAEGIPKIYLAANSGARIGLAEEIKHMFQVAWVDPEDPHKGFKYLYLTPQ
EYTRISSLNSVHCTHIEEEGESRYVITDVIGKEDGLGVENLRGSGTIAGESSLAYEEIVT
ISLVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMH
NNGVSHVTVPDDFEGVYTILEWLSYVPKDNHSPVPIITPTDPIDREIEFFPSRAPYDPRW
MLAGRPHPNLKGCWQSGFFDQGSFKEILAPWAQTVVTGRARLGGIPVGVIAVETRTVEVV
VPADPANLDSEAKIIQQAGQVWFPDSAYKTAQVIKDFNQEKLPLMIFANWRGFSGGMKDM
YDQVLKFGAYIVDGLRQYKQPILIYIPPYGELRGGSWVVLDSTINPLCIEMYADKESRGG
VLEPEGTVEIKFRKKDLVKAMRRIDSTYKKLVEQLGNSELSDKDRKDLEGRLKAREDLLL
PIYHQVAVQFADLQDTPGRMLEKGVISDVLEWKTSRTFLYWRLRRLLLEDQVKQEILRVS
SELSHVHIQSMLRRWFVETEGAVKAYLWDNNQMVVQWLEQHWQAGDGLRSAIHENIKYLK
RDSALKTIRGLVQENPEVAVDSIMYMSQYIGPAERARLTHLLSTMDSPMDSPMDNPAST
NT seq
7380 nt
NT seq
+upstream
nt +downstream
nt
atgatcctgctctttttcctatcttgtctgattgtctcctgcctgaccttgtcctggtta
aaaatctgggggaaaatgaccgactccacaccagccaccaagaaccactcggagggagac
atcctcctgaaccaggagtcccttccagcatctgacagctcagaggagccactgcagaaa
aacggagacagcagctcggggccaaagactcctgaccaggctgagccggcctccctgaaa
ggtcgcaaagatgcctctctgaaaagaacctcccggccgcccccatatcggaatcctcag
aagagcccccttccctcccgggatgcctccccagccaatgggacagggactcggagcccg
gaggccccagacaccaatgtcctgtcctcaccaaccaggccccaggcccgaggcagagcc
ctctccagagaagaccagaaacaggcgcacatcaaatcgcagctgatgactaaattcatc
ctgggctccttcgatgacaactcctctgacgaggacgccagcgtgggctcccgggagtct
tcccgcaggggcagccgggccagcctggggggcctgcccctggaggctgctcggaccgca
ggcgattccgagtcctccgtccccacgatgaggcccagcatgtctgggctccacctggtg
aggaggggccgagaacagaagaaggtgagcctgcacagagacttcaccgtagcttcacca
gccgagtttgtaacacgctttgggggcgatcgagtcatcgagaaggtgctcattgccaac
aatggcatcgccgctgtgaagtgcatgcgctccatccgcaggtgggcctacgagatgttc
cgaaacgagcgggccatccgatttgtagtcatggtgactccagaggacctcaaagccaac
gcagagtacatcaagatggccgatcagtatgtccccgtgccagggggccccaacaacaac
aactatgccaacgtggagctcatcgtggacattgccaagagaatccctgtgcaggcggtg
tgggctggctggggccacgcctccgaaaaccccaaacttccggagctcctgtgcaagcac
gagattgctttcttaggcccccccagtgaggccatgtgggccctgggagataagatcgcc
tccaccatcgtggcccagacgctgcagattccaacactgtcctggagtggaagcggtctg
acggtggaattggcagaagacgacctgcagcaggggacaagagtctgtgtcccggaggac
atttaccaccagggttgtgtgaaagacgtagaggaaggcttggaggcagcagaaaggatt
ggttttcccttgatgatcaaagcttcagaaggcggtggagggaaaggaatccggaaggtg
gagagcgccgaggacttcccgatccttttcagacaagtacagagcgagatcccgggctcc
cctgtctttctcatgaagctggcccagcacgcccgtcacctggaggtccagatccttgcc
gaccagtacggcaacgccgtgtccctgtttgggcgagactgctccatccagcggaggcat
cagaagatcattgaggaggcacctgccaccatcgccaccccggccgtgttcgagttcatg
gagcagtgtgccgtccgcctggccaagacagtgggctacgtgagcgcgggaacggtggaa
tacctgtacagccaggatggcagcttctacttcttggagctgaacccccgcctgcaggtg
gagcacccctgcacggaaatgatcgccgatgtcaacctgccggctgcccagctgcagatc
gccatgggtgtgccgctacaccggctgaaagacatccgccttctgtacggagagtcaccg
tgggggatgacgcccatttctttcgatgccccttccaacccgcccatcccccgaggccac
gttattgcagccagaatcaccagtgaaaatcccgatgaggggtttaagccgagctctgga
acagtccaggaactgaatttccgcagcagcaagaacgtgtggggttatttcagcgtggct
gctgccggtggcttacacgagtttgccgattcccagttcgggcactgcttctcctgggga
gagaaccgggaagaggccatttcgaacatggtggtggctttgaaggaactgtccatccgg
ggcgacttcaggaccaccgtggagtacctcattaacctcctggagacggagagtttccag
aacaacgacatcgacactgggtggttggatcacctcattgctgagaaagtgcaggcggaa
aagccagacatcatgctcggggtggtgtgcggagccttgaacgtggccgatgcgatgttc
agaacctgcatgacggatttcttacactcgctggaaaggggccaggtcctccctgcagcg
tccctgcggaacactgtggacgtggaattgatttacggaggctttaagtacatcctcaag
gtggcccggcagtctctaaccatgttcgtcctcatcatgaatggctgtcacatcgagatc
gacgcccaccggctgaatgacggcgggcttctgctgtcctacggtggtaacagctacacg
acctacatgaaggaggaggtggacagttaccggattaccattggcaacaagacatgtgtg
tttgagaaggagaatgaccccacggtgctgagagccccttcggctgggaagctgacgcag
tacacggtggaggacgggggctacgtggaggcggggggcagctacgctgagatagaggtg
atgaagatgatcatgtccctgaacgtgcaggagagtggccgggtgaagtacatcaagcgc
ccgggcgccgtgctggaagcgggctgtgtggtggccaggctggagctcgacgacccctct
aaagtgcacccggcccggccattcacaggagagctcccccaccagccaactctgcccatc
atgggggagaaactgaaccaggtcttccacagcgccctggaaaacctgatgaacgtcatg
aacggctactgcctgcccgagcccgtgtttaccataaagctgaaggagtgggtgcagaag
ctcatgatgaccctccgccacccgtcgctgccactgctggagctgcaggagatcatgacc
agtgtgtcgggccgcatccctgcccccgtggagaagttggtccgcagggtgatggcccag
tacgctagcaacatcacctcagtgctctgccagttccccagccagcagatagccaccatc
ctggactgccacgcggccacgctgcagcggaaggctgaccgggaagtcttcttcatgaac
acccagagcatcgtgcagctggtccagagataccgcagcgggacccgcggctacatgaag
gcagtggtgttggatctgctgaaaagatacctacaagtcgagcaccatttccaacaagcc
cattacgacaagtgtgtgataaacctcagggagcagctgaagccagacatgtcccaggtg
ctggactgcatcttttcccacgcgcaggtggccaagaagaaccagctggtgatcatgttg
attgatgaactctgtggcccagacccttccctgtcggaggagctgacctccatcctcaac
gagctcacccagctgaacaagagcgagcactgcaaagtggccctgcgagccagacaggtc
ctgatcgcctcccacctcccctcctacgagctgaggcacaaccaggtggagtccattttc
ctgtctgccatcgacaggtatggccaccagttctgcccggaaaacctcaagaaattgata
ctctcggaaacgaccatatttgacgtgctgcctactttcttctatcacactaacgaggtc
gtgtgcatggcgtccttggaggtctatgtgcggaggggctacatcgcctacgagttaaac
agcctgcagcaccggcagctcccagacggcacctgtgtggtggaattccagttcatgctg
ccctcctcccacccaaaccggatggctgtgcccatcagcgacaccaaccctgacctgctg
agacacagcacggagctcttcatggacagtggcttctccccgctgtcccagcggatgggt
gccatggtcgccttcaggagatttgaggagttcaccaggaactttgatgaggtcatctcc
tgcttcgccaacgtggctgaggacaccccgctcttcaggaaggcccagacgtccatgtac
tgtgaggaggacggcaagaacctcagggaagagcccatccacatcctgaacgtggccatc
cagtacgccgaccacctggaagacgaggagctagtgccgattttgcggaccttcgtgcag
tccaagaagaacatcctcgtggattacggactccggagaatcacgttcctgatcgcccag
gagaaagaatttcccaagtttttcacgttcagagccagagatgagtttgcagaagatcgc
atttaccgtcacctggagcccgccttggccttccagctggagctcagccggatgcgcaat
ttcgacctgaccgccgtgccctgcgccaaccacaagatgcacctttacctgggtgctgcc
agggtaaaggagggcgtggaagtgacagaccaccggttcttcatccgtgccatcatccgg
cactcagacctgatcacaaaggaagcctccttcgagtacctgcagaatgagggtgagcgg
ctgctcctggaggccatggacgagctggaggtggcgttcaacaacaccagcgtgcgcacc
gactgcaaccacatcttcctcaacttcgtgcccactgtcatcatggacccctacaagatc
gaggagtcggtgcgtcccatggtcatgcgctatggcagcaggttgtggaagctccgcgtg
ctgcaggctgaggtcaagatcaacatccgcgagaccacctccggcagcgccattcccatc
cgcctgttcatcaccaacgagtcaggctactacctggatatcagcctctacaaagaagtc
accgaccccagatcgggaaatatcatgtttcacggctttggcaacaaacaagggccccag
cacgggatgctgatcaacaccccctacgtcactaaggacctgcttcaggccaagcggttc
caggcccagtccctggggaccacctacgtgtacgacttcccggaactgttcaggcaggct
ctctttaaaatgtggggctccccagacaagtaccccaaagacatcctgacgtacacggag
ctcgtgctggacccccagggccagctggtggagatgaaccgactgcccggcggaaacgag
gtgggcatggtggccttcaaaatgaggttcaagacccgggagtatccggaggggcgggac
gcgatcgtcatcagcaacgacatcaccttccgcatcgggtcctttggcatgggcgaagac
ctgctgtacctgcgggcgtccgagatggcccgggccgaaggcatccccaaaatctacctc
gcggccaacagcggggcccggatcggcctcgccgaagagattaaacacatgttccaggtg
gcctgggtggacccagaagacccccacaaaggatttaaatacctgtacctgaccccccaa
gagtacaccagaatcagctccctgaactccgtccactgcacacacatcgaggaagaaggg
gaatccaggtacgtgatcacggatgtcatcgggaaggaggacggcctgggcgtggagaac
ctgcggggctccggcacgatcgcaggggagtcctccctggcttacgaagagatcgtcacc
attagcctggtgacctgccgagccctcgggatcggcgcctacttggtgaggctgggccag
cgcgtgatccaggtggaaaactcccacatcattctaacaggagccagcgcactcaacaag
gtcctgggcagagaggtttacacgtccaacaaccagctgggcggcgtgcagatcatgcac
aacaacggtgtctcccacgtcaccgtgccggacgacttcgagggcgtttacaccatcctg
gagtggctgtcctatgtgccaaaggataatcacagcccggtccctatcatcacgcccacg
gaccccattgacagagaaattgagtttttcccctcgagagccccgtacgacccccggtgg
atgcttgcaggacggcctcacccaaatctgaagggatgctggcagagtggattcttcgac
cagggcagtttcaaggaaatcctggctccctgggcccagaccgtggtgacgggacgcgca
aggctggggggcatccctgttggagtgatcgccgtggagacgcggacagtggaggtggtg
gtgcccgcagaccctgccaacctggattccgaggcaaagatcatccagcaggcaggccag
gtgtggttcccggactcggcctataagacggcccaggtcatcaaggacttcaaccaggag
aagctgcccctgatgatctttgccaactggaggggcttctccggcggcatgaaagacatg
tatgatcaggtgctgaagttcggcgcctacatcgtggacggcctcaggcagtacaagcag
cccatcctcatctacatcccgccctatggggagctccggggaggctcctgggtggtcctg
gactccaccatcaaccctctgtgcatagagatgtatgcggacaaagagagcagggggggt
gtcctggagccagagggaacagtggagattaagttccgaaagaaagatctggtaaaggcc
atgagaaggatcgacagcacttacaagaagctcgtggagcagttaggcaattctgagctc
tcggacaaggaccgcaaggacctggagggccggctgaaggcccgggaggacctgctgctg
cccatctaccaccaggtggcggtgcagtttgccgacctccaagacacacccggcaggatg
ctggagaagggcgtcatctctgacgtcctggagtggaagacctcgcgcaccttcctgtac
tggcgcctgcgccgcctcctgctggaggaccaggtcaagcaggagatcctgcgggtcagc
agtgagctgagccacgtgcacatccagtccatgctgcgccgctggttcgtggagacggag
ggggctgtcaaggcctacctgtgggacaacaaccagatggtggtgcagtggctggaacag
cactggcaggcaggggacggcctgcgctccgccatccatgagaacatcaagtacctgaag
cgagactcggcgctcaagaccatccggggcctggtccaagaaaaccccgaggtggcagtg
gacagcataatgtacatgagccagtacattggcccagccgagcgggcccgcctcactcac
ctcctgtccaccatggacagccccatggacagccccatggacaaccccgcctccacctga
DBGET
integrated database retrieval system
