KEGG   Desmodus rotundus (common vampire bat): 112313353
Entry
112313353         CDS       T05907                                 
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
  KO
K00161  pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
Organism
dro  Desmodus rotundus (common vampire bat)
Pathway
dro00010  Glycolysis / Gluconeogenesis
dro00020  Citrate cycle (TCA cycle)
dro00620  Pyruvate metabolism
dro00785  Lipoic acid metabolism
dro01100  Metabolic pathways
dro01200  Carbon metabolism
dro01210  2-Oxocarboxylic acid metabolism
dro04066  HIF-1 signaling pathway
dro04922  Glucagon signaling pathway
dro05230  Central carbon metabolism in cancer
dro05415  Diabetic cardiomyopathy
Module
dro_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:dro00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    112313353 (PDHA1)
   00020 Citrate cycle (TCA cycle)
    112313353 (PDHA1)
   00620 Pyruvate metabolism
    112313353 (PDHA1)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    112313353 (PDHA1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    112313353 (PDHA1)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    112313353 (PDHA1)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    112313353 (PDHA1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    112313353 (PDHA1)
Enzymes [BR:dro01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     112313353 (PDHA1)
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C
Other DBs
NCBI-GeneID: 112313353
NCBI-ProteinID: XP_024425669
LinkDB
Position
Unknown
AA seq 390 aa
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPAVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLSDGQEACCVGLEAGINPTDHLITAYRA
HGFTYTRGLSVREILTELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQVFETYNMAALWKLPCIFICENNGYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAVAHCRSGKGPIVMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSNDPPFEVRGTNQWIKFKSVS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgaggaagatgctcgctgccgtctcccgcgtgttgtcgggcgctgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaag
tgtgatcttcaccggctggaggagggccccgctgtcacaacagtgctcaccagggaggat
gggctcaaatactacaggatgatgcagactgttcgccgaatggagttaaaggccgatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtctgatggtcaggaagcttgt
tgtgtgggcctggaagctggtataaatcccacagaccatctgatcaccgcctatcgggct
catggcttcacctatactcgtgggctttctgtacgagaaattctcacagagcttacagga
cgaagaggaggttgtgctaaaggaaaaggaggatcaatgcatatgtatgccaaaaatttc
tacgggggcaatggcatcgttggagctcaggtgcccctgggagctgggattgctctggcc
tgcaagtataatgggaaagatgaggtctgtttgaccttatatggtgatggagctgctaat
cagggtcaggtattcgaaacttataatatggcagctttgtggaaattaccttgtattttc
atctgtgaaaataatggctacggaatggggacatctgttgagagagcagcagccagcact
gattactacaagagaggtgacttcattcctgggctgagggtagatggaatggatatcctg
tgtgtccgggaggcaacaaagtttgcagtggcccattgtagatctggaaaggggcccata
gtgatggagctgcagacctaccgctaccatggacacagcatgagtgatcctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagcaagagtgaccctatcatgcttctc
aaggacagaatggtgaacagcaaccttgccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgctgcccaatttgcaacagctgatcctgaaccacct
ttggaagaactaggctatcacatctactccaacgatccaccttttgaagttcgcggtaca
aatcagtggatcaagtttaagtctgtcagttaa

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