Desmodus rotundus (common vampire bat): 112317856
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Entry
112317856 CDS
T05907
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro00010
Glycolysis / Gluconeogenesis
dro00020
Citrate cycle (TCA cycle)
dro00620
Pyruvate metabolism
dro00785
Lipoic acid metabolism
dro01100
Metabolic pathways
dro01200
Carbon metabolism
dro01210
2-Oxocarboxylic acid metabolism
dro04066
HIF-1 signaling pathway
dro04922
Glucagon signaling pathway
dro05230
Central carbon metabolism in cancer
dro05415
Diabetic cardiomyopathy
Module
dro_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
112317856 (PDHA2)
00020 Citrate cycle (TCA cycle)
112317856 (PDHA2)
00620 Pyruvate metabolism
112317856 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
112317856 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
112317856 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
112317856 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
112317856 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
112317856 (PDHA2)
Enzymes [BR:
dro01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
112317856 (PDHA2)
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Paralog
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
112317856
NCBI-ProteinID:
XP_024430719
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MKKMLVAAVSRVLSGVAQKPASRVLVASCNYSNDATFEIKKCDLYRLEEGPPVTAVLTRE
DGLKYYKMMQIIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHIITSYR
AHGFCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYSKNFYGGNGIVGAQGPLGAGVSL
ASKYKGNNEVCLTVYGDGAANQGQIAEAYNMAALWKLPCIFICENNQYGMGTAVERASAS
TDYYKRGNFIPGLRVDGMDVLCVREAIKFAADYCRSGRGPIVMELQTYRFHGHSMSDPGV
SYRTREEVQNVRNKRDPIMLLKDRMVNSNLTSVEELKEIDVEVRKEIDDAAQFAITDPEP
PLEEIGHHIYSDSPPFEVRGANQWVKFKSIS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatgctcgtagctgctgtgtctcgcgtgttgtccggagtcgcccagaagcct
gctagcagagtgctggtggcatcctgcaactattcaaatgatgctacatttgaaattaag
aaatgtgatctttatcggttggaagaaggccccccagtcacagcggtgctcactcgggag
gatgggctcaaatactacaagatgatgcagattattcgccgaatggaattgaaggcagat
cagctgtataaacagaaattcattcgtggtttttgtcacctgtgtgatggtcaggaggct
tgctgtgtgggcctggaggccgggataaatcccaccgaccacatcatcacatcctaccgg
gctcacggcttttgctacactcgtggactctctgtccgatcaattctggcagagctgaca
ggacgaagaggaggctgtgctaaagggaaaggaggatccatgcatatgtattccaagaac
ttctacgggggcaacggcattgtgggcgctcagggacccctgggagctggggtttctctg
gcctctaaatataaaggaaacaatgaggtctgcttgactgtgtacggggatggtgctgcc
aatcagggtcagatagctgaagcttacaatatggcagccttgtggaaattaccatgtatt
ttcatctgtgagaataaccagtatggaatgggaacagctgttgagagagcatcagccagc
actgattactacaagagaggaaattttatccctggactaagggtagatggaatggatgtg
ctatgtgttcgggaggcaattaagtttgcagctgactattgtagatctggaagggggccc
atagtgatggagctgcagacataccgttttcacggacacagtatgagtgatcctggagtc
agttaccgcacacgagaagaagttcaaaatgtaagaaataagcgtgatccgattatgctt
ctcaaagatagaatggtaaacagcaaccttaccagtgttgaagaattgaaggaaattgat
gttgaagtgaggaaagaaattgatgatgcagcccagtttgctataactgatcctgaacca
cctttggaagaaataggccatcatatctacagtgacagtcccccctttgaagttcgaggt
gcaaatcagtgggtcaagtttaagtccatcagttaa
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