Desmodus rotundus (common vampire bat): 112320488 Help Entry 112320488         CDS       T05907                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism dro  Desmodus rotundus (common vampire bat) Pathway dro00230   Purine metabolism dro01100   Metabolic pathways dro01522   Endocrine resistance dro04015   Rap1 signaling pathway dro04022   cGMP-PKG signaling pathway dro04024   cAMP signaling pathway dro04062   Chemokine signaling pathway dro04072   Phospholipase D signaling pathway dro04114   Oocyte meiosis dro04211   Longevity regulating pathway dro04213   Longevity regulating pathway - multiple species dro04261   Adrenergic signaling in cardiomyocytes dro04270   Vascular smooth muscle contraction dro04371   Apelin signaling pathway dro04540   Gap junction dro04611   Platelet activation dro04713   Circadian entrainment dro04714   Thermogenesis dro04723   Retrograde endocannabinoid signaling dro04724   Glutamatergic synapse dro04725   Cholinergic synapse dro04726   Serotonergic synapse dro04727   GABAergic synapse dro04728   Dopaminergic synapse dro04750   Inflammatory mediator regulation of TRP channels dro04911   Insulin secretion dro04912   GnRH signaling pathway dro04913   Ovarian steroidogenesis dro04914   Progesterone-mediated oocyte maturation dro04915   Estrogen signaling pathway dro04916   Melanogenesis dro04918   Thyroid hormone synthesis dro04921   Oxytocin signaling pathway dro04923   Regulation of lipolysis in adipocytes dro04924   Renin secretion dro04925   Aldosterone synthesis and secretion dro04926   Relaxin signaling pathway dro04927   Cortisol synthesis and secretion dro04928   Parathyroid hormone synthesis, secretion and action dro04934   Cushing syndrome dro04935   Growth hormone synthesis, secretion and action dro04970   Salivary secretion dro04971   Gastric acid secretion dro04972   Pancreatic secretion dro04976   Bile secretion dro05012   Parkinson disease dro05030   Cocaine addiction dro05031   Amphetamine addiction dro05032   Morphine addiction dro05034   Alcoholism dro05163   Human cytomegalovirus infection dro05166   Human T-cell leukemia virus 1 infection dro05200   Pathways in cancer dro05207   Chemical carcinogenesis - receptor activation dro05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:dro00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     112320488 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     112320488 (ADCY5)    04371 Apelin signaling pathway     112320488 (ADCY5)    04072 Phospholipase D signaling pathway     112320488 (ADCY5)    04024 cAMP signaling pathway     112320488 (ADCY5)    04022 cGMP-PKG signaling pathway     112320488 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     112320488 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     112320488 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     112320488 (ADCY5)    04062 Chemokine signaling pathway     112320488 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     112320488 (ADCY5)    04923 Regulation of lipolysis in adipocytes     112320488 (ADCY5)    04912 GnRH signaling pathway     112320488 (ADCY5)    04913 Ovarian steroidogenesis     112320488 (ADCY5)    04915 Estrogen signaling pathway     112320488 (ADCY5)    04914 Progesterone-mediated oocyte maturation     112320488 (ADCY5)    04921 Oxytocin signaling pathway     112320488 (ADCY5)    04926 Relaxin signaling pathway     112320488 (ADCY5)    04935 Growth hormone synthesis, secretion and action     112320488 (ADCY5)    04918 Thyroid hormone synthesis     112320488 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     112320488 (ADCY5)    04916 Melanogenesis     112320488 (ADCY5)    04924 Renin secretion     112320488 (ADCY5)    04925 Aldosterone synthesis and secretion     112320488 (ADCY5)    04927 Cortisol synthesis and secretion     112320488 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     112320488 (ADCY5)    04270 Vascular smooth muscle contraction     112320488 (ADCY5)   09154 Digestive system    04970 Salivary secretion     112320488 (ADCY5)    04971 Gastric acid secretion     112320488 (ADCY5)    04972 Pancreatic secretion     112320488 (ADCY5)    04976 Bile secretion     112320488 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     112320488 (ADCY5)    04727 GABAergic synapse     112320488 (ADCY5)    04725 Cholinergic synapse     112320488 (ADCY5)    04728 Dopaminergic synapse     112320488 (ADCY5)    04726 Serotonergic synapse     112320488 (ADCY5)    04723 Retrograde endocannabinoid signaling     112320488 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     112320488 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     112320488 (ADCY5)    04213 Longevity regulating pathway - multiple species     112320488 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     112320488 (ADCY5)    04714 Thermogenesis     112320488 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112320488 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     112320488 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     112320488 (ADCY5)    05163 Human cytomegalovirus infection     112320488 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     112320488 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     112320488 (ADCY5)    05031 Amphetamine addiction     112320488 (ADCY5)    05032 Morphine addiction     112320488 (ADCY5)    05034 Alcoholism     112320488 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     112320488 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     112320488 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     112320488 (ADCY5) Enzymes [BR:dro01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      112320488 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC HILPDA Motif Other DBs NCBI-GeneID:  112320488 NCBI-ProteinID:  XP_024433695 LinkDB All DBs Position Unknown AA seq 1208 aa AA seqDB search MSGSKSVSPPGYAAQTAAAPASRGSSEHRSAWGAADSRANGYPHAPGGSARGSTKKPGGA VTPQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR ADELEAGAIESDEASGEDGSSAGSGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRY FFRLNQSSLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLATAVGVILVMAVLCNRAAF HQDHMGLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLS GVLLSALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRE CIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFA DIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADH AHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLAN HMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEK AMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPE DEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFL FICFVQITIVPHSVFMLSFYLTCFVLLTLVVFVSVIYSCVKLFPAPLQTFSRKIVRSKMN STLVGVFTITLVFLSAFVNMFLCNSKDLSGCLADEHNISASQVNACHVVESAVNYSLGDE QGFCGSAWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLALMLAIELIYVLIVEVPSVT LFDNADLLVTANAIDVSNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTAR LDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVM FASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAAS GLNDSTYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARK PQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYF LNGGPPLS NT seq 3627 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaagcgtgagccccccgggctacgcggcgcagacagccgcggcgccg gcgtcccggggaagctcggaacaccgctcggcgtggggagcggccgattcccgcgccaat gggtacccccacgcccctgggggttcggcccgcggctccacgaagaaacctgggggggcg gtgaccccgcagcagcagcagcggctagccagccgctggcgcagcgacgacgacgacgat cctccgctgagtggcgatgatcccctggccgggggcttcggtttcagcttccgatccaag tccgcctggcaggagcgcggcggcgacgactgcggccgcggcagtcgcaggcagcggcgg gcggacgagctggaggccggcgccatcgagagcgacgaggcgtctggagaagacggcagc tcggcgggctcgggccctggcgcggtgctgtccctgggcgcctgctgcctggcgctgctg cagattttccgctctaagaagttcccgtcggacaagcttgagcggctgtaccagcgctac ttcttccgtctcaaccagagcagcctcaccatgctgatggccgtgctggtgctagtgtgc ctcgtcatgctggccttccacgcggcgcggccaccgctccagttgccctacctggccgtg ctggcgaccgccgtgggcgtgatcctcgttatggcggtgctctgcaaccgtgccgcgttc caccaggaccacatgggcctggcctgctatgcgctcattgccgtggtgctggccgtccag gtggtgggcctgctgctgcctcagccgcgcagcgcctcggagggtatctggtggacggtg ttcttcatctacaccatctacacgctgctgccggtgcgcatgcgggccgcggtactcagc ggggtgctcctgtctgccctccacttggccatagccctacgcaccaacgcccaggatcag ttcctgctcaagcagcttgtctccaatgtcctcattttctcctgcaccaacatcgtgggt gtctgcacccactacccggctgaggtttcccagagacaggccttccaggagacccgagag tgcatccaggcgaggctccactctcagcgggagaaccagcaacaggagaggctcctgctg tctgtccttccccgtcacgttgccatggagatgaaagcagacatcaatgccaagcaagag gatatgatgttccataagatttacatccagaaacatgacaacgtgagcatcctgtttgct gacatcgagggcttcaccagcctggcatcgcagtgcaccgcccaagagctggtcatgacc ctcaacgagctcttcgcccgcttcgacaagctggctgcggagaatcactgtttacgtatt aagatcctgggggattgttattactgcgtctcggggctgcctgaagcgagggccgaccac gcccactgctgcgtggagatgggcatggacatgattgaggccatctcgttggtccgggag gtgacaggggtgaacgtgaacatgcgcgtgggaattcacagcgggcgagtacactgcggt gtccttggtctcaggaagtggcagttcgacgtctggtctaacgacgtcacgctggccaac cacatggaggctggaggcaaggctgggcgcatccacatcaccaaggccacactcaactac ctgaacggcgactacgaggtggagccaggctgcgggggcgagcgcaacgcctacctcaag gagcacagcatcgagaccttcctcatcctgcgctgcacccagaagcggaaagaagagaag gccatgattgccaagatgaatcgccagagaaccaactccattgggcacaacccaccacac tggggggccgagcgccccttctacaaccacctgggtggcaaccaggtgtccaaggagatg aagcggatgggcttcgaagaccccaaggacaagaacgcccaggaaagtgcaaaccccgag gatgaagtggacgaatttctgggccgtgccattgacgccaggagcattgacaggctgcgg tcggagcatgttcgcaagttcctcttgaccttcagggagcctgacttagagaagaagtac tccaagcaggtggatgaccgattcggtgcctacgtggcgtgtgcctcgcttgtcttcctc ttcatctgctttgtccagatcaccatcgtgccccactccgtgttcatgttgagtttctac ctgacctgttttgtgttgctgaccttggtggtatttgtgtccgtgatctactcctgcgtg aagctcttcccggcccccctgcagaccttctccaggaagatcgtgcggtccaagatgaac agcaccctggttggggtgttcaccatcaccctggtgttcctgtcggcttttgtcaacatg ttcctgtgcaactccaaggacctgtccggctgcctggcagatgagcataacatcagcgcc agccaggtcaacgcgtgccacgtggtggagtcggctgtcaactacagcctgggggatgag cagggcttctgcggcagtgcctggcccaactgcaacttccccgagtacttcacctacagc gtgctgctcagcctgctggcctgctccgtgttcctgcagatcagctgcatcgggaagctg gcgctcatgctggccattgagctcatctacgtgctcatcgtcgaggtgcccagtgtgaca ctctttgacaatgccgaccttctggtcaccgccaatgccatcgacgtcagcaacaatggg acctcccagtgccccgaacacgcgaccaaggtggcgctgaaggtggtgacgcccatcatc atctcagtcttcgtgctggccctgtacctgcacgcccagcaggtggagtccaccgcccgc ctcgacttcctctggaaactgcaggccacggaggagaaagaggagatggaggagctgcag gcctacaaccggcggctgctgcacaacatcctgcccaaagacgtggccgcccacttcctg gcccgcgagcggcgcaacgacgagctctactaccagtcgtgtgagtgcgtggctgtcatg ttcgcctccatcgccaacttctccgagttctatgtggagctggaggccaacaacgagggt gtcgagtgccttcggcttctcaacgagatcatcgccgacttcgatgagatcatcagcgag gatcggtttaggcagttggaaaagatcaagaccatcggcagcacctacatggccgcttcc ggccttaatgattccacctacgacaaggtgggcaagacccacatcaaagctctggccgac tttgccatgaagctgatggaccaaatgaagtacatcaatgagcactccttcaacaacttc cagatgaagattgggctcaacatcggccccgtggtggccggggtgatcggcgcccgcaag cctcagtacgacatctggggcaacacggtgaatgtggccagccgcatggacagcaccggt gtgcctgaccgcatccaggtcacaacagacatgtaccaggtgctggctgccaacacctac cagctggagtgccggggtgtggtcaaggtcaagggcaaaggcgagatgatgacctacttc ctcaatggagggcccccactcagttag

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