KEGG   Desmodus rotundus (common vampire bat): 112321896
Entry
112321896         CDS       T05907                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
dro  Desmodus rotundus (common vampire bat)
Pathway
dro01522  Endocrine resistance
dro04010  MAPK signaling pathway
dro04015  Rap1 signaling pathway
dro04068  FoxO signaling pathway
dro04071  Sphingolipid signaling pathway
dro04114  Oocyte meiosis
dro04148  Efferocytosis
dro04218  Cellular senescence
dro04261  Adrenergic signaling in cardiomyocytes
dro04370  VEGF signaling pathway
dro04380  Osteoclast differentiation
dro04550  Signaling pathways regulating pluripotency of stem cells
dro04611  Platelet activation
dro04613  Neutrophil extracellular trap formation
dro04620  Toll-like receptor signaling pathway
dro04621  NOD-like receptor signaling pathway
dro04622  RIG-I-like receptor signaling pathway
dro04625  C-type lectin receptor signaling pathway
dro04657  IL-17 signaling pathway
dro04658  Th1 and Th2 cell differentiation
dro04659  Th17 cell differentiation
dro04660  T cell receptor signaling pathway
dro04664  Fc epsilon RI signaling pathway
dro04668  TNF signaling pathway
dro04670  Leukocyte transendothelial migration
dro04714  Thermogenesis
dro04722  Neurotrophin signaling pathway
dro04723  Retrograde endocannabinoid signaling
dro04728  Dopaminergic synapse
dro04750  Inflammatory mediator regulation of TRP channels
dro04912  GnRH signaling pathway
dro04914  Progesterone-mediated oocyte maturation
dro04917  Prolactin signaling pathway
dro04926  Relaxin signaling pathway
dro04932  Non-alcoholic fatty liver disease
dro04933  AGE-RAGE signaling pathway in diabetic complications
dro04935  Growth hormone synthesis, secretion and action
dro04936  Alcoholic liver disease
dro05014  Amyotrophic lateral sclerosis
dro05020  Prion disease
dro05022  Pathways of neurodegeneration - multiple diseases
dro05132  Salmonella infection
dro05133  Pertussis
dro05135  Yersinia infection
dro05140  Leishmaniasis
dro05142  Chagas disease
dro05145  Toxoplasmosis
dro05152  Tuberculosis
dro05161  Hepatitis B
dro05163  Human cytomegalovirus infection
dro05167  Kaposi sarcoma-associated herpesvirus infection
dro05169  Epstein-Barr virus infection
dro05170  Human immunodeficiency virus 1 infection
dro05171  Coronavirus disease - COVID-19
dro05205  Proteoglycans in cancer
dro05208  Chemical carcinogenesis - reactive oxygen species
dro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
dro05415  Diabetic cardiomyopathy
dro05417  Lipid and atherosclerosis
dro05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112321896 (MAPK12)
   04015 Rap1 signaling pathway
    112321896 (MAPK12)
   04370 VEGF signaling pathway
    112321896 (MAPK12)
   04668 TNF signaling pathway
    112321896 (MAPK12)
   04068 FoxO signaling pathway
    112321896 (MAPK12)
   04071 Sphingolipid signaling pathway
    112321896 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    112321896 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    112321896 (MAPK12)
   04218 Cellular senescence
    112321896 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    112321896 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    112321896 (MAPK12)
   04613 Neutrophil extracellular trap formation
    112321896 (MAPK12)
   04620 Toll-like receptor signaling pathway
    112321896 (MAPK12)
   04621 NOD-like receptor signaling pathway
    112321896 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    112321896 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    112321896 (MAPK12)
   04660 T cell receptor signaling pathway
    112321896 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    112321896 (MAPK12)
   04659 Th17 cell differentiation
    112321896 (MAPK12)
   04657 IL-17 signaling pathway
    112321896 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    112321896 (MAPK12)
   04670 Leukocyte transendothelial migration
    112321896 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    112321896 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    112321896 (MAPK12)
   04917 Prolactin signaling pathway
    112321896 (MAPK12)
   04926 Relaxin signaling pathway
    112321896 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    112321896 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    112321896 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    112321896 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    112321896 (MAPK12)
   04722 Neurotrophin signaling pathway
    112321896 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    112321896 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    112321896 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    112321896 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    112321896 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    112321896 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112321896 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    112321896 (MAPK12)
   05161 Hepatitis B
    112321896 (MAPK12)
   05171 Coronavirus disease - COVID-19
    112321896 (MAPK12)
   05163 Human cytomegalovirus infection
    112321896 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112321896 (MAPK12)
   05169 Epstein-Barr virus infection
    112321896 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112321896 (MAPK12)
   05135 Yersinia infection
    112321896 (MAPK12)
   05133 Pertussis
    112321896 (MAPK12)
   05152 Tuberculosis
    112321896 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    112321896 (MAPK12)
   05140 Leishmaniasis
    112321896 (MAPK12)
   05142 Chagas disease
    112321896 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    112321896 (MAPK12)
   05020 Prion disease
    112321896 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    112321896 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112321896 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    112321896 (MAPK12)
   05415 Diabetic cardiomyopathy
    112321896 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    112321896 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    112321896 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    112321896 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    112321896 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dro01001]
    112321896 (MAPK12)
Enzymes [BR:dro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     112321896 (MAPK12)
Protein kinases [BR:dro01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   112321896 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 RIO1 APH Kdo Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 112321896
NCBI-ProteinID: XP_024435274
LinkDB
Position
Unknown
AA seq 367 aa
MSSPPPARRGFYRQEVTKTAWEVRSVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KLEKLSEDRVQFLVYQMLKGLKYIHAAGVVHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSAGCIMAEMITGKTLFKGNDHLDQLKEILK
VTGTPPDEFVQRLQSADAKDYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDGERRV
TAAEALTHPYFESLQDAEDEPKAQKYDESFDDVDRTLDEWKRDTYKEVLSFKPPRQLGAK
ASKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctctccgccgcccgcccgcaggggcttttaccgccaggaggtgaccaagaccgcc
tgggaggtgcgctcggtgtaccaggaccttcagcccgtgggctccggcgcctatggcgca
gtgtgctcggccgtggacagccgcacaggcgccaaggtggccatcaagaagttgtaccgg
ccctttcagtcggagctgttcgccaagcgcgcctaccgcgagctgcgcctcctgaagcac
atgcgccacgagaacgtgatcgggctgctggacgtgttcaccccagacgagaccctggat
gatttcacagacttctacctggtcatgccgttcatgggcaccgacctgggcaagctcatg
aagctcgagaagctgagtgaggaccgggtccagttccttgtctaccagatgctgaaaggg
ttgaagtacatccacgctgctggcgtcgttcacagggacctgaagccgggcaacctggca
gtgaatgaggactgcgagctgaagatcctggacttcggcctggccaggcaggctgacagc
gagatgaccgggtatgtggtgactcggtggtaccgggcacccgaggtcattttgaattgg
atgcactatacacagacagtggacatctggtctgcgggctgcatcatggccgagatgatc
acagggaagacactgttcaagggcaacgaccacctggaccagctgaaagagatcttgaag
gtgacggggacacctcctgatgagtttgtgcagaggctgcagagtgctgatgcgaaggac
tacatgaagggcctccctgagttggagaagaaggattttgcctctatcctgaccaacgcg
agccctctggccgtgaacctcctggagaaaatgctggtgctggatggggagcggcgggtg
acggcagccgaggcgctgactcacccctacttcgagtcgctgcaggacgcagaggatgag
cccaaggcccagaagtatgacgagtcctttgacgacgtggaccgcacgctggacgagtgg
aagcgtgacacgtacaaagaggtgctcagctttaagcctccccggcagctgggggccaag
gcctccaaggagacggccctgtga

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