Dipodomys spectabilis (banner-tailed kangaroo rat): 122100098
Help
Entry
122100098 CDS
T07891
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp00010
Glycolysis / Gluconeogenesis
dsp00020
Citrate cycle (TCA cycle)
dsp00620
Pyruvate metabolism
dsp00785
Lipoic acid metabolism
dsp01100
Metabolic pathways
dsp01200
Carbon metabolism
dsp01210
2-Oxocarboxylic acid metabolism
dsp04066
HIF-1 signaling pathway
dsp04922
Glucagon signaling pathway
dsp05230
Central carbon metabolism in cancer
dsp05415
Diabetic cardiomyopathy
Module
dsp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
122100098 (Pdha1)
00020 Citrate cycle (TCA cycle)
122100098 (Pdha1)
00620 Pyruvate metabolism
122100098 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
122100098 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
122100098 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
122100098 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
122100098 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
122100098 (Pdha1)
Enzymes [BR:
dsp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
122100098 (Pdha1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
122100098
NCBI-ProteinID:
XP_042526430
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLLGVAQKPATRVLVASRNFANDATFEIKKCDLHRLDEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgccgccgtctcccgcgtgttgttgggcgttgcccagaagccggca
accagagtgctagtggcatcgcgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgaccttcaccgactggatgaaggccctcccgttacaactgtgctcaccagagaggat
gggctcaaatactataggatgatgcagactgtgcgcagaatggagttaaaagctgatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgc
tgtgtggggctcgaggccggtataaaccccacagaccatctcatcacagcctaccgggct
catggcttcaccttcactaggggtctttctgttcgtgaaattctcgcagagctaacagga
cgaagaggaggttgtgctaaagggaaaggaggatctatgcacatgtatgccaagaacttc
tacgggggcaatggtatcgttggagctcaggtacccctgggagctgggattgctctggcc
tgtaagtataatggaaaagatgaagtctgtttgacactatatggtgatggtgctgctaat
cagggtcagatatttgaagcttacaatatggcagcattatggaaattaccgtgcattttc
atctgtgagaataaccgctatggaatgggaacgtctgttgagagagccgcagccagtact
gattactacaagagaggagactttatccctgggctgagggtagatgggatggatatcttg
tgtgtccgagaggccacgaagtttgcagctgcctattgtagatctgggaagggacctatc
ctgatggagctgcagacttaccgttaccatggacacagcatgagtgaccctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaatagcaatctggccagtgttgaagaattgaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgctgcccagtttgccacagctgatcctgagccacca
ttggaagagctcggctatcacatctacagcagcgatccaccatttgaagtgcgtggtgcc
aaccagtggatcaagtttaagtcagtcagttaa
DBGET
integrated database retrieval system
