KEGG   Dipodomys spectabilis (banner-tailed kangaroo rat): 122111503
Entry
122111503         CDS       T07891                                 
Symbol
Mapk14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
dsp  Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp01522  Endocrine resistance
dsp04010  MAPK signaling pathway
dsp04015  Rap1 signaling pathway
dsp04068  FoxO signaling pathway
dsp04071  Sphingolipid signaling pathway
dsp04114  Oocyte meiosis
dsp04148  Efferocytosis
dsp04218  Cellular senescence
dsp04261  Adrenergic signaling in cardiomyocytes
dsp04370  VEGF signaling pathway
dsp04380  Osteoclast differentiation
dsp04550  Signaling pathways regulating pluripotency of stem cells
dsp04611  Platelet activation
dsp04613  Neutrophil extracellular trap formation
dsp04620  Toll-like receptor signaling pathway
dsp04621  NOD-like receptor signaling pathway
dsp04622  RIG-I-like receptor signaling pathway
dsp04625  C-type lectin receptor signaling pathway
dsp04657  IL-17 signaling pathway
dsp04658  Th1 and Th2 cell differentiation
dsp04659  Th17 cell differentiation
dsp04660  T cell receptor signaling pathway
dsp04664  Fc epsilon RI signaling pathway
dsp04668  TNF signaling pathway
dsp04670  Leukocyte transendothelial migration
dsp04714  Thermogenesis
dsp04722  Neurotrophin signaling pathway
dsp04723  Retrograde endocannabinoid signaling
dsp04728  Dopaminergic synapse
dsp04750  Inflammatory mediator regulation of TRP channels
dsp04912  GnRH signaling pathway
dsp04914  Progesterone-mediated oocyte maturation
dsp04917  Prolactin signaling pathway
dsp04926  Relaxin signaling pathway
dsp04932  Non-alcoholic fatty liver disease
dsp04933  AGE-RAGE signaling pathway in diabetic complications
dsp04935  Growth hormone synthesis, secretion and action
dsp04936  Alcoholic liver disease
dsp05014  Amyotrophic lateral sclerosis
dsp05020  Prion disease
dsp05022  Pathways of neurodegeneration - multiple diseases
dsp05132  Salmonella infection
dsp05133  Pertussis
dsp05135  Yersinia infection
dsp05140  Leishmaniasis
dsp05142  Chagas disease
dsp05145  Toxoplasmosis
dsp05152  Tuberculosis
dsp05161  Hepatitis B
dsp05163  Human cytomegalovirus infection
dsp05167  Kaposi sarcoma-associated herpesvirus infection
dsp05169  Epstein-Barr virus infection
dsp05170  Human immunodeficiency virus 1 infection
dsp05171  Coronavirus disease - COVID-19
dsp05205  Proteoglycans in cancer
dsp05208  Chemical carcinogenesis - reactive oxygen species
dsp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
dsp05415  Diabetic cardiomyopathy
dsp05417  Lipid and atherosclerosis
dsp05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dsp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122111503 (Mapk14)
   04015 Rap1 signaling pathway
    122111503 (Mapk14)
   04370 VEGF signaling pathway
    122111503 (Mapk14)
   04668 TNF signaling pathway
    122111503 (Mapk14)
   04068 FoxO signaling pathway
    122111503 (Mapk14)
   04071 Sphingolipid signaling pathway
    122111503 (Mapk14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    122111503 (Mapk14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    122111503 (Mapk14)
   04218 Cellular senescence
    122111503 (Mapk14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    122111503 (Mapk14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    122111503 (Mapk14)
   04613 Neutrophil extracellular trap formation
    122111503 (Mapk14)
   04620 Toll-like receptor signaling pathway
    122111503 (Mapk14)
   04621 NOD-like receptor signaling pathway
    122111503 (Mapk14)
   04622 RIG-I-like receptor signaling pathway
    122111503 (Mapk14)
   04625 C-type lectin receptor signaling pathway
    122111503 (Mapk14)
   04660 T cell receptor signaling pathway
    122111503 (Mapk14)
   04658 Th1 and Th2 cell differentiation
    122111503 (Mapk14)
   04659 Th17 cell differentiation
    122111503 (Mapk14)
   04657 IL-17 signaling pathway
    122111503 (Mapk14)
   04664 Fc epsilon RI signaling pathway
    122111503 (Mapk14)
   04670 Leukocyte transendothelial migration
    122111503 (Mapk14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    122111503 (Mapk14)
   04914 Progesterone-mediated oocyte maturation
    122111503 (Mapk14)
   04917 Prolactin signaling pathway
    122111503 (Mapk14)
   04926 Relaxin signaling pathway
    122111503 (Mapk14)
   04935 Growth hormone synthesis, secretion and action
    122111503 (Mapk14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    122111503 (Mapk14)
  09156 Nervous system
   04728 Dopaminergic synapse
    122111503 (Mapk14)
   04723 Retrograde endocannabinoid signaling
    122111503 (Mapk14)
   04722 Neurotrophin signaling pathway
    122111503 (Mapk14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    122111503 (Mapk14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    122111503 (Mapk14)
  09159 Environmental adaptation
   04714 Thermogenesis
    122111503 (Mapk14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    122111503 (Mapk14)
   05208 Chemical carcinogenesis - reactive oxygen species
    122111503 (Mapk14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    122111503 (Mapk14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    122111503 (Mapk14)
   05161 Hepatitis B
    122111503 (Mapk14)
   05171 Coronavirus disease - COVID-19
    122111503 (Mapk14)
   05163 Human cytomegalovirus infection
    122111503 (Mapk14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122111503 (Mapk14)
   05169 Epstein-Barr virus infection
    122111503 (Mapk14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    122111503 (Mapk14)
   05135 Yersinia infection
    122111503 (Mapk14)
   05133 Pertussis
    122111503 (Mapk14)
   05152 Tuberculosis
    122111503 (Mapk14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    122111503 (Mapk14)
   05140 Leishmaniasis
    122111503 (Mapk14)
   05142 Chagas disease
    122111503 (Mapk14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    122111503 (Mapk14)
   05020 Prion disease
    122111503 (Mapk14)
   05022 Pathways of neurodegeneration - multiple diseases
    122111503 (Mapk14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122111503 (Mapk14)
   05418 Fluid shear stress and atherosclerosis
    122111503 (Mapk14)
   05415 Diabetic cardiomyopathy
    122111503 (Mapk14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    122111503 (Mapk14)
   04932 Non-alcoholic fatty liver disease
    122111503 (Mapk14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    122111503 (Mapk14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    122111503 (Mapk14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dsp01001]
    122111503 (Mapk14)
Enzymes [BR:dsp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     122111503 (Mapk14)
Protein kinases [BR:dsp01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   122111503 (Mapk14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 122111503
NCBI-ProteinID: XP_042540294
LinkDB
Position
Unknown
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVVSFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctatcggcaggagctgaacaagaccatctgggaggtg
ccggagcggtaccagaacctgtccccggtgggctccggcgcctacggctctgtgtgtgct
gcttttgacacaaagactgggttgcgtgtggctgtgaagaagctgtccaggccgtttcag
tccatcatccatgccaaaaggacatatagagagctgcgcttactcaagcacatgaagcat
gagaatgtgattggtcttttggatgtcttcacacctgcaaggtctctggaggaattcaac
gatgtgtatctggtgacccacctcatgggggctgatctgaacaatattgtaaaatgtcag
aaactcacggatgaccatgttcaattcctcatctaccagattctccgaggtctaaagtat
atacattcagctgacataattcacagggacctaaaacccagtaatcttgctgtgaatgag
gactgtgagctaaagattcttgattttggactggctcgacatactgatgatgaaatgaca
ggttatgtggccaccaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagtggatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acattgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgagcttttgaagaaaatctcctcagagtctgcaagaaactatattcag
tctttgacccagatgcctaagatgaactttgcaaatgtatttattggtgccaaccccctg
gctgtcgatttgctggagaagatgctcgtattggactcggataagcggattacagcagcc
caagccctggcacatgcctactttgcgcagtaccacgatccagatgatgagccagtagct
gatccctacgaccagtcatttgaaagcagggacctccttatagatgaatggaaaagcctg
acgtatgatgaagttgtcagctttgtgccaccaccccttgaccaagaagagatggagtcc
tga

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