Dipodomys spectabilis (banner-tailed kangaroo rat): 122122824
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Entry
122122824 CDS
T07891
Symbol
Hsd11b1l
Name
(RefSeq) hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp00140
Steroid hormone biosynthesis
dsp00980
Metabolism of xenobiotics by cytochrome P450
dsp01100
Metabolic pathways
dsp05204
Chemical carcinogenesis - DNA adducts
Module
dsp_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
122122824 (Hsd11b1l)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
122122824 (Hsd11b1l)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
122122824 (Hsd11b1l)
Enzymes [BR:
dsp01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
122122824 (Hsd11b1l)
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Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Motif
Other DBs
NCBI-GeneID:
122122824
NCBI-ProteinID:
XP_042553160
LinkDB
All DBs
Position
Unknown
AA seq
287 aa
AA seq
DB search
MKVLLFTGLGALLFAYYWDDNFDPTSLRGARVLLTGASAGVGEELAYHYARLGSHLVLTA
PTEALLQKVVGNCRKLGAPKVFYIAADMASSEAPEHVVQFALDKLGGLDYLVLNHMGSTP
AGMRVRSAQTTRWLMQVNFLSYVQLTSLALPSLTDSKGSLVVVSSLLGRVPASFSIPYSA
AKFALDGFFGSLRRELDVQDVNVAVTLCVLGLRDRASAAEGVRGVSRARTAPGPKAALAV
IRGGATRASGVFYPWRLHLLCLLRGWLPRPPAWFVRQDLNVSAAAAA
NT seq
864 nt
NT seq
+upstream
nt +downstream
nt
atgaaggtgttgctcttcacggggctgggggccctgctcttcgcttactactgggatgac
aacttcgaccccaccagccttcggggagcccgcgtgctgctgacgggggccagtgccggc
gtgggcgaggagctggcctatcactacgcccggctgggctcacacctggtgctcactgcc
cccaccgaggccctcctgcagaaggtggtagggaactgtcggaagctgggtgcacccaag
gtcttctacattgcggcggacatggcctcctctgaggctcccgagcacgtggtgcagttt
gccctggacaagctgggcgggctggactaccttgtgctgaatcacatgggcagcaccccg
gccggcatgcgggtccgcagcgcccagaccacacgctggctcatgcaggtgaacttcctg
agttacgtgcagctgacttcgctggcgctgcccagcctgacggacagcaagggctctctg
gtggtggtgtcctcgttgctcggccgcgtgcccgcgtccttctccatcccgtactccgcg
gccaagttcgcgctcgacggcttcttcggctccctgcggcgggagctggacgtgcaggac
gtgaacgtggcggtcaccttgtgcgtcctgggcctccgcgatcgcgcctccgccgccgag
ggggtcaggggcgtctcgagggccaggacggctcccgggcccaaggcggccctggctgtg
atccgtggcggggccacacgggcctcgggcgtcttctacccgtggcgactgcacctgctg
tgcctgctgcggggctggctcccgcgcccgcccgcctggttcgtgcgccaggacctcaac
gtgtccgcggccgccgcggcctga
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