Dipodomys spectabilis (banner-tailed kangaroo rat): 122127230
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Entry
122127230 CDS
T07891
Symbol
Pdha2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp00010
Glycolysis / Gluconeogenesis
dsp00020
Citrate cycle (TCA cycle)
dsp00620
Pyruvate metabolism
dsp00785
Lipoic acid metabolism
dsp01100
Metabolic pathways
dsp01200
Carbon metabolism
dsp01210
2-Oxocarboxylic acid metabolism
dsp04066
HIF-1 signaling pathway
dsp04922
Glucagon signaling pathway
dsp05230
Central carbon metabolism in cancer
dsp05415
Diabetic cardiomyopathy
Module
dsp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
122127230 (Pdha2)
00020 Citrate cycle (TCA cycle)
122127230 (Pdha2)
00620 Pyruvate metabolism
122127230 (Pdha2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
122127230 (Pdha2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
122127230 (Pdha2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
122127230 (Pdha2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
122127230 (Pdha2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
122127230 (Pdha2)
Enzymes [BR:
dsp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
122127230 (Pdha2)
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Paralog
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
122127230
NCBI-ProteinID:
XP_042557791
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MKKMLASVVSRVLGATQKPPLRVLLTSCNYSKDATIDIKSCDLYRLDGGPASSTLLTRDD
GLKYYRAMQIVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGIEAAIKPTDNVITSYRA
HGICYTRGLSVKSILAELTGRRGGCAKGKGGSMHMYAKHFFGGNGIVGAQVPLGAGIALA
CKYLGKRDICLAMYGDGAANQGQIAEAYNMAALWKLPCVFICENNRYAMGTAVERAAAST
DYYKRGNFIPGLKVNGMDVLCVREATRFAADHCRAGKGPIVMELQTYRYHGHSMSDPGVS
YRTREEIQTMRTKSDPIMLLQEKMISHKLSSVEELKEIDVEVRKEIEEAAQFATTDPEPS
LDELGHHLYHSNPPFDVRGANQWIKYKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaagatgctggcttctgtggtctcccgcgtgttgggggccacccagaagccccct
ctcagagtactgctgacctcctgcaactattccaaggatgctaccattgacattaagagc
tgcgatctttaccggctggacgggggccccgcgtcctccaccttgctcacccgggacgac
gggctcaagtactaccgggccatgcagatcgtccgccggatggaactgaaggcggaccag
ctctacaaacagaaatttatccgtggcttctgccacctgtgcgacggccaggaagcttgc
tgcgtggggatcgaggcggccatcaagcccacggataacgtgatcacctcctaccgggcg
cacggcatctgctacacgcgcggactctcggtcaagtcgatcctggcggagctgacaggg
cgcaggggaggatgcgccaaaggcaagggcggctccatgcacatgtacgccaagcacttc
ttcgggggcaacggcatcgtgggcgcgcaggtgcccctgggcgcggggatcgccctggcc
tgcaagtacctggggaaacgggacatctgcctggccatgtacggcgacggggctgccaac
cagggccagatcgccgaggcctacaacatggcagcgctgtggaagctgccgtgcgtgttc
atctgcgagaacaaccgctacgccatgggcacggcggtggagagggcggcggccagcacg
gattactacaagcggggcaacttcatcccgggcctcaaggtgaacggcatggatgtgctg
tgcgtgcgcgaggccaccaggttcgcggcggatcactgccgggccgggaagggccccatc
gtgatggagctgcagacctaccggtaccacgggcacagcatgagcgacccgggcgtgagc
taccgcacgcgcgaggagatccagaccatgaggaccaagagcgaccccatcatgctgctc
caggagaagatgatcagccacaagctcagcagcgtggaagagctcaaggagatcgacgtg
gaggtgaggaaggagatcgaggaggccgcccagttcgccaccaccgaccccgagcccagc
ctggacgagctgggccatcacctctaccacagcaacccgcccttcgacgtccggggggcc
aaccagtggatcaagtacaaatccatcagttaa
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