KEGG   Drosophila serrata: 110184122
Entry
110184122         CDS       T06108                                 
Name
(RefSeq) dihydropyrimidine dehydrogenase [NADP(+)]
  KO
K00207  dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2]
Organism
dsr  Drosophila serrata
Pathway
dsr00240  Pyrimidine metabolism
dsr00410  beta-Alanine metabolism
dsr00770  Pantothenate and CoA biosynthesis
dsr00983  Drug metabolism - other enzymes
dsr01100  Metabolic pathways
Module
dsr_M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate
Brite
KEGG Orthology (KO) [BR:dsr00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    110184122
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    110184122
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    110184122
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    110184122
Enzymes [BR:dsr01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.2  dihydropyrimidine dehydrogenase (NADP+)
     110184122
SSDB
Motif
Pfam: DHO_dh Fer4_20 Fer4_21 Pyr_redox_2 Fer4_7 Fer4_10 Dus NAD_binding_8 Fer4_9 Pyr_redox Pyr_redox_3 Fer4_6 Fer4_2 Fer4 Fer4_17 FAD_oxidored Fer4_8
Other DBs
NCBI-GeneID: 110184122
NCBI-ProteinID: XP_020808187
LinkDB
Position
Unknown
AA seq 1033 aa
MSPPQLLSKDSPDIEDLLSLNPRVKTQCSVVPTKQTKENKKHWKRNADHAAPPCTTLAND
FSDIKHTTLSERGALEEAARCLKCADAPCQKSCPTQLDIKSFITSIANKNFYGAAKAIFS
DNPLGLTCGMVCPTSDLCVGGCNLQASEAGAINIGGLQQFATEVFKQMGVSQRRTPHAEA
NPLAGKIALLGGGPASLSCATFLGRLGYRDVTIYERRSYLGGLSAAEIPQYRLPIDAVNF
EIDLVKNLGVRIETGRSLSTKDLTIQGLLSSGHDAVFVGIGLPEPKLNPIFAGLDPSNGF
YTSKNFLPLVSDGSKPGLCACKASAGLPKLHGNVIVLGAGDTAFDCATSALRCGARRVFV
VFRKGSSGIRAVPEEVELARDERCELLPYLSPRKVIVKDGLITAMEFCRTEQNDKDEWVE
DEEQTQRLKANFVISAFGSGLEDADVKAALAPLQFRGELPIVDRVTMQSSLSQVFLGGDL
AGVANTTVESVNDGKVAAWSIHCQLQGLPLDTPAALPLFYTDIDAVDISVEMCGLKFENP
FGLASAPPTTSTAMIRRAFEQGWGYVVTKTFGLDKDLVTNVSPRIVRGTTSGYKYGPQQG
CFLNIELISEKRAEYWLKSIGELKRDFPEKIVIASIMCSFNEDDWTELAIKAEQSGADAL
ELNLSCPHGMGERGMGLACGQDPELVEQISRWVRKAVKLPFFIKLTPNITDIASIAAAAK
RGGADGGSAINTVQGLMGLKADATAWPAIGKEQRTTYGGVSGNATRPMALKAISDIARRV
PDFPILGIGGIDSGEVALQFIQAGATVLQICSSVQNQDFTVIEDYCTALKALLYLKANPP
PVNGAFWDGQSPPTPVHQKGKPVVRLTGEGNVTLGFFGPYQRERDIKMADLRSKQGALWD
AEQAAQGPTAVGNGTTPKAVPRIKDLIGAALERIGPYNKLDNKQQKVALIDDDMCINCGK
CYMTCADSGYQAIEFDKDTHIPHVNDDCTGCTLCVSVCPIIDCITMVPKKIPHVIKRGLE
EKTYYTHALSQCQ
NT seq 3102 nt   +upstreamnt  +downstreamnt
atgagtccgccgcaactcttgagcaaagactccccggatattgaggatctgctgtcgctg
aatccacgcgtcaagacccagtgctctgtggtgcccaccaagcagacgaaggagaacaaa
aagcactggaagcgaaatgctgaccatgctgcaccgccctgcaccacgctggcgaatgac
ttctcggacattaagcacacgacgctgtcggaacgtggagctctggaagaggcggctagg
tgcctgaagtgcgcagatgcgccatgccagaagtcctgccccacgcagctggacattaaa
agcttcatcacgagcattgcgaacaagaacttttatggggccgccaaggcaatcttctcg
gacaatcctttgggactcacctgtggcatggtctgccccacaagtgacctctgtgttgga
ggctgcaatctccaggcctcggaggcgggtgccattaacattggtggcctgcagcagttc
gccaccgaagtgtttaagcagatgggggtgagccagcgtagaacgccgcatgcggaggcc
aacccgttggccggaaagattgctctgctgggaggaggcccagcctccctgtcctgcgcc
accttcctggggcgtctgggctatcgggatgtgaccatctatgagcgcaggagctacctg
ggcggactgagtgctgctgagattccgcaataccgtcttcccatagatgcggtcaacttt
gagatcgatctggtcaagaatctgggtgtacgcatcgaaaccggtcgctccctgagcacc
aaggatctgactattcagggtctgctctcctctggtcacgatgccgtcttcgttggcatt
ggtctgccggaacccaagctcaacccgatcttcgctggcctagatcccagcaatggcttc
tacacatccaagaacttcctgccactggtgtctgatggctccaaaccgggactttgcgcc
tgcaaggcatccgccggattgcccaagcttcacggcaacgtcattgtcctgggagccgga
gacacagccttcgattgtgccacctcggcgctgagatgcggtgcccggcgagtgtttgtg
gtgttccgtaaaggatcttcgggcatccgggcggtgcctgaggaagtggagctggctcgc
gacgaacggtgcgagctgctgccttacttaagtccccggaaggtgattgtcaaggatggg
ctgatcaccgccatggagttctgccgcacggagcaaaacgacaaggacgaatgggtggag
gatgaggagcagacgcagcgtctgaaggccaactttgtcatctctgcatttggctcgggc
ctagaggatgcggatgttaaggcagccctggctccactgcagttccgcggagagctaccc
attgtcgacagggtcaccatgcagagcagtctgagccaggtgttccttggcggagatctg
gccggtgtggctaataccacggtggagtcggttaacgatggcaaagtggccgcctggagc
atccactgtcagcttcagggacttcccctggacacgccagctgccctgccactgttctac
acggacatcgatgccgttgacatatccgttgagatgtgcggcctgaagttcgagaatcca
ttcggtctggcctcggccccgcccaccaccagcacggccatgatccgacgcgccttcgag
cagggttggggttatgtggtcaccaagacgttcggcctcgacaaggatctcgtcaccaat
gtgtcacctcgcatcgttaggggcaccacttccggctacaagtacggaccccagcagggt
tgcttcctgaacatcgagctcatctcggaaaagcgcgccgagtactggttgaagtcgatt
ggagaactgaagcgcgacttcccagagaagatcgtaattgccagcatcatgtgcagcttc
aacgaggacgattggacagagctggccatcaaggcggagcagtcgggtgctgatgctctg
gagctcaatctgtcctgcccgcacggcatgggcgagcggggaatgggtttggcctgtggc
caggatcccgaactggtggagcagatctcccgatgggtgaggaaggccgtcaagctgccc
ttcttcatcaagctgacgcccaacatcacggatatcgcttccattgcggctgcggcaaag
cgcggaggagctgacggcggatcggccattaacacggtccaggggctgatgggtctcaag
gcggatgctactgcctggccggcgattggtaaggagcaaaggaccacctatggtggtgtc
tctggcaacgccacccgtcccatggccctgaaggccatctcggacattgctagacgcgtg
ccagatttccccattctcggcatcggcggcatcgattccggtgaggtggctctgcagttc
attcaggcaggtgccacggtgctccagatctgttcgtctgtccagaatcaggacttcact
gtcatcgaggattattgcacggcattgaaggctctgctctatttgaaggccaatccgccg
ccggtgaacggcgccttctgggatggccagtcgccacccacaccggttcatcaaaagggc
aagccagtagtccgtctaaccggcgagggtaacgtcactcttggcttcttcggaccctat
cagcgggagcgggacatcaagatggcggatctgcgcagcaagcagggcgctctctgggat
gccgaacaggcggcacaaggtcccacggcagtcggaaatggaactacaccaaaggcagtg
cctaggattaaggacttaattggcgccgctctggagaggattgggccgtacaacaagctg
gacaacaagcagcagaaggtggctctgattgacgatgacatgtgcatcaactgtggcaag
tgctatatgacttgcgccgattccggataccaggccattgagttcgacaaggacacgcac
attccgcacgtgaacgacgattgcacgggctgcacgctctgcgtctccgtgtgtccaatt
atcgactgcatcaccatggtaccgaaaaagatcccacacgtgatcaagagggggctggag
gagaagacctactacacccacgccctcagccaatgccagtag

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