Drosophila willistoni: 6648399
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Entry
6648399 CDS
T01067
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
dwi
Drosophila willistoni
Pathway
dwi00010
Glycolysis / Gluconeogenesis
dwi00020
Citrate cycle (TCA cycle)
dwi00620
Pyruvate metabolism
dwi00785
Lipoic acid metabolism
dwi01100
Metabolic pathways
dwi01200
Carbon metabolism
dwi01210
2-Oxocarboxylic acid metabolism
Module
dwi_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dwi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
6648399
00020 Citrate cycle (TCA cycle)
6648399
00620 Pyruvate metabolism
6648399
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
6648399
Enzymes [BR:
dwi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
6648399
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
6648399
NCBI-ProteinID:
XP_023035012
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Position
XL
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AA seq
634 aa
AA seq
DB search
MIMLKQGRATLPKLLSGVTHQTSALQLRRLLAICKRATWREWLNRRHKSETSNSNSTLTL
ENTFKCYDLETGPPLDVELSREDALSMYTKMVEVRRLEIIAAEFYKQKKIRGFCHLYNGQ
EAVAVGMTSVMRKTDTVITAYRCHAWTYLMGVSMYALLAELLGVRTGCSRGKGGSMHMYA
DNYYGGNGIVGAQVPMGAGIALAHRYKDDDGVCIVCYGDGAANQGQIFEAYNMAKLWCLP
CIFVCENNEYGMGTETSRASANTDFYMRGQYIPGLWVDGNQVLAVRSATQFAIDFAQSNG
PIVLEMFTYRYMGHSMSDPGTSYRTRDEVQNVRETRDPITNFRNQVVRLCLASEEELKQI
DDNVKKQVGLDAKKALQDREVDEHELTADVYAKNVEPKIRGVSGYNLEHRQVTEVCLGKP
KPTPAKDMKDVPVGDAALLAAQAGKMKKDGKKTDEAADGDKTKPSDGDKTKPADGDKTKT
PTKKGEGEESQSNAKVPPAKGETKAAGTPPVTTPPPAATPPATTPGKTPAAPPGKTPAAT
AGKAAAAPPGKTPAATAGKAAAAPPGKTPAATPAKTPAGAPGKVTAAPAPSGKTPASPQP
KNPPATSPSSPPKAEPPGSGGAPKSPKPKNTPKK
NT seq
1905 nt
NT seq
+upstream
nt +downstream
nt
atgataatgctaaaacaaggccgagcgaccctgccaaaacttctttctggtgtcactcat
caaacatcagccttgcaattgcgaagacttttggccatttgcaaacgagcgacatggagg
gaatggttaaacagacgccacaaatctgaaacaagcaacagcaatagtacgctgaccctg
gagaatacattcaagtgttacgatctggaaactggaccacccttggatgtggagctgtca
cgcgaagatgctctgtccatgtacactaagatggttgaggtgcgtcgcttggagataata
gcagcagaattctataaacaaaagaagatacgaggcttctgtcatctgtacaatggccag
gaggcggtagctgtgggcatgacatcggtaatgcgaaaaacggatacagtaataacggcc
taccgctgccatgcctggacatatctcatgggtgtttcgatgtatgccctgctggccgaa
ctcttgggtgttcgcactggctgcagtcgcggcaagggcggttccatgcacatgtatgcg
gataactattacggaggcaatggcatagtgggtgcccaagtgccgatgggcgctggcatt
gctctggcccatcgctataaggacgatgatggcgtgtgcattgtctgctacggcgacggt
gcggccaatcagggccagatattcgaagcctacaacatggccaagctttggtgtttgccg
tgtatatttgtgtgtgagaacaatgagtatggcatgggcacagaaacgagtcgagcgtcg
gccaatacagacttctatatgcgtggacagtatatacctggcctctgggtggacggcaat
caggtgctggccgtgcgcagtgccacacagtttgccatcgatttcgctcagtcgaatggc
cccattgttcttgaaatgtttacttatcgttatatgggtcactccatgtccgatccggga
acttcgtatcggacccgcgacgaggtacagaatgttcgcgaaacccgggatcccatcacg
aatttccgtaaccaagttgtaaggctatgcctagccagcgaagaggaactgaagcaaatc
gacgataatgttaagaagcaagtgggattggatgccaagaaagctttgcaagatcgggaa
gtcgatgagcacgagctgacagcggatgtgtatgccaagaatgtggagcccaaaattcgt
ggcgtatccggttataatctagagcatcgccaggtgacagaagtgtgtctgggcaagcca
aaacccacgccagccaaggatatgaaggatgtgccggtgggcgatgcagcacttcttgcc
gcccaagcgggaaaaatgaagaaagatggcaaaaaaacggacgaagcagcagatggcgat
aaaaccaaaccatcagacggtgataaaaccaaaccagcagatggtgataaaaccaaaaca
cccacaaaaaagggcgaaggggaagagtctcaatcgaacgccaaagtaccaccggcaaag
ggagaaactaaagcagccggaacaccaccagtaacgacaccacctcctgctgcaacacca
ccagctacaacaccagggaaaactccagctgcaccaccaggaaaaactccagcagcaaca
gcaggcaaagctgcagctgcaccaccaggaaaaactccagcagcaacagcaggcaaagct
gcagctgcaccaccaggaaaaactccagctgcaacacctgcgaaaactccagctggagcc
ccgggcaaagttacagctgctccagcgccatcaggaaaaactccagcctcaccacagccg
aaaaatccacccgctacatcaccgtcttcaccacccaaagccgagccacctggctcaggc
ggcgcaccaaagtcacctaaacccaaaaatacgccaaaaaagtag
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