Drosophila willistoni: 6648400
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Entry
6648400 CDS
T01067
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, mitochondrial isoform X2
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
dwi
Drosophila willistoni
Pathway
dwi00010
Glycolysis / Gluconeogenesis
dwi00020
Citrate cycle (TCA cycle)
dwi00620
Pyruvate metabolism
dwi00785
Lipoic acid metabolism
dwi01100
Metabolic pathways
dwi01200
Carbon metabolism
dwi01210
2-Oxocarboxylic acid metabolism
Module
dwi_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dwi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
6648400
00020 Citrate cycle (TCA cycle)
6648400
00620 Pyruvate metabolism
6648400
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
6648400
Enzymes [BR:
dwi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
6648400
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
6648400
NCBI-ProteinID:
XP_002071128
FlyBase:
FBgn0227265
UniProt:
B4NEE5
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Position
XL
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AA seq
404 aa
AA seq
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MLRSLSRISELPIVVRQLQKSASAAQGGLSKTSTNNNYATEATIEVNRPFKLHRLDEGPA
TTVKLTKDEALKYYTQMQTIRRIETAAGNLYKEKIIRGFCHLYSGQEACAVGMKAAMRDV
DNIISAYRVHGWTYLMGVSPNGVLAELTGVQGGCARGKGGSMHMYSPNFYGGNGIVGAQV
PLGAGVGLACKYKGNGGMCLALYGDGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGT
SSERASCNTDYYTRGDALPGIWVDGMDVLAVRSATEFAINYVNTHGPLVMETNTYRYSGH
SMSDPGTSYRTREEIQEVRQKRDPITSFKELCIELGLITADEVKAIDLKVRKEIDEATAF
AKSDAELAVSHLWTDVYSNNLEPKLRGPISYNLDHIQERKGVNH
NT seq
1215 nt
NT seq
+upstream
nt +downstream
nt
atgttgcgctctctgtcacgcattagcgaattaccaatcgttgttagacaattgcaaaaa
agtgcatcagcagcacagggtggtctcagcaaaaccagcaccaacaacaactatgccacg
gaagctacaatcgaagtgaatcgtcccttcaagctgcaccgtctggacgagggacccgcg
accacggtgaaactgaccaaggatgaggctctcaagtattacacacaaatgcaaacgatt
cgtcgtattgagacagcggccggcaatctgtacaaagagaagatcattcgtggcttctgt
catttgtattccggccaggaggcgtgtgctgtgggcatgaaggcggccatgcgagatgtg
gataacatcatttcggcctatcgtgttcacggatggacctatctgatgggtgtatcgccc
aatggagtcctagccgaattgaccggagtccagggtggttgtgctcgcggtaaaggaggc
tccatgcacatgtattcgcccaatttctatggcggcaatggcattgttggcgctcaggtg
cctctgggtgctggcgttggtttggcctgcaagtacaagggtaatggtggcatgtgcctg
gctctttatggtgacggtgccgccaatcagggacaagtgttcgaggcctacaacatggcc
tatttgtggaaattgccggtaatctttgtctgcgagaataacaactatggcatgggcacc
agttcggagcgtgcttcctgcaacacggattactatactcgtggtgatgccctgcctggc
atttgggttgatggcatggatgtgctggctgtgcgcagtgcaactgaatttgccattaac
tatgtgaatactcatggaccgttggttatggagacgaatacgtatcgttattcgggtcat
tccatgtccgatccgggcacatcttatcgtacacgtgaagagattcaggaagtgcgtcag
aagcgtgatcccatcacatcattcaaggagctgtgcattgagctgggtctcattacggcc
gatgaggttaaggccattgatctgaaggtacgcaaggaaatcgatgaggccaccgccttt
gccaagagtgatgccgagttggctgtcagccatctctggaccgatgtctactccaacaat
ctggaacccaaactgcgtggacccatttcttacaatttggatcacattcaggagcgcaag
ggtgtcaaccattaa
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