Equus asinus (ass): 106838751
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Entry
106838751 CDS
T04645
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform X1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
eai
Equus asinus (ass)
Pathway
eai01521
EGFR tyrosine kinase inhibitor resistance
eai04151
PI3K-Akt signaling pathway
eai04217
Necroptosis
eai04380
Osteoclast differentiation
eai04550
Signaling pathways regulating pluripotency of stem cells
eai04620
Toll-like receptor signaling pathway
eai04621
NOD-like receptor signaling pathway
eai04630
JAK-STAT signaling pathway
eai04658
Th1 and Th2 cell differentiation
eai04659
Th17 cell differentiation
eai05140
Leishmaniasis
eai05145
Toxoplasmosis
eai05152
Tuberculosis
eai05160
Hepatitis C
eai05161
Hepatitis B
eai05162
Measles
eai05163
Human cytomegalovirus infection
eai05164
Influenza A
eai05165
Human papillomavirus infection
eai05166
Human T-cell leukemia virus 1 infection
eai05167
Kaposi sarcoma-associated herpesvirus infection
eai05168
Herpes simplex virus 1 infection
eai05169
Epstein-Barr virus infection
eai05171
Coronavirus disease - COVID-19
eai05200
Pathways in cancer
eai05203
Viral carcinogenesis
eai05212
Pancreatic cancer
eai05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
106838751 (JAK1)
04151 PI3K-Akt signaling pathway
106838751 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
106838751 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
106838751 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
106838751 (JAK1)
04621 NOD-like receptor signaling pathway
106838751 (JAK1)
04658 Th1 and Th2 cell differentiation
106838751 (JAK1)
04659 Th17 cell differentiation
106838751 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
106838751 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
106838751 (JAK1)
05203 Viral carcinogenesis
106838751 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
106838751 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
106838751 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
106838751 (JAK1)
05161 Hepatitis B
106838751 (JAK1)
05160 Hepatitis C
106838751 (JAK1)
05171 Coronavirus disease - COVID-19
106838751 (JAK1)
05164 Influenza A
106838751 (JAK1)
05162 Measles
106838751 (JAK1)
05168 Herpes simplex virus 1 infection
106838751 (JAK1)
05163 Human cytomegalovirus infection
106838751 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
106838751 (JAK1)
05169 Epstein-Barr virus infection
106838751 (JAK1)
05165 Human papillomavirus infection
106838751 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
106838751 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
106838751 (JAK1)
05140 Leishmaniasis
106838751 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
106838751 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eai01001
]
106838751 (JAK1)
Enzymes [BR:
eai01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
106838751 (JAK1)
Protein kinases [BR:
eai01001
]
Non-receptor tyrosine kinases
JAK family [OT]
106838751 (JAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
ABC1
SH2
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
106838751
NCBI-ProteinID:
XP_014708469
UniProt:
A0A8C4LPA7
LinkDB
All DBs
Position
16:46621798..46744119
Genome browser
AA seq
1153 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTEVNQEAPEPGLEVLFYLSDREPLRLGRGEYTAEEL
CIRAAQECCISPLCHNLFALYDENTRLWSAPNRTITVDDKTCLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYDKKKVTDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSMHDLKVKYLATLETLTKHYGAEIFETSELLISSENEMN
RFHLNDSGNILYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKYKKDEEKNKIR
EEWNNFSYFPEITHVVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGGEEGMYVLRWSCTDFDNILMTVT
CFEKSEVLGGQKQFKNFQIEVQKGCYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGT
LVDYRDDEGTPEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFNVAKQLASALSYLEDKDLVHGNVCTKNLL
LAREGIDSECGPFIKLSDPGIPITVLSRQERLERIPWIAPECVDDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI
MRDINKLEEQNPDIVSERKPAAEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS
GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSQQYVHRDLAARNVLVESEHQVKIGD
FGLTKAIERDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD
SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPHCPDEVYQLMRKCWEFQPSSRTT
FQNLIEGFEALLK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgaga
agctccaagaagacggaggtgaaccaggaggccccggaaccagggctggaggtgctcttc
tacctgtcggatagggagcccctccggctgggccgcggggagtacacggccgaggagctg
tgcatcagggccgcgcaggagtgctgcatctctcctctgtgtcacaacctctttgccctg
tatgacgagaacaccaggctctggtctgctcccaaccgcaccatcacggtggacgacaag
acatgcctccggctccattaccggatgaggttctatttcaccaactggcatgggaccaac
gataatgagcagtctgtatggcgccattctccaaagaagcagaaaaatggctacgataaa
aagaaagttacagatgcaacccctctcctcgacgccagctcactggagtatctgtttgct
cagggacagtatgatttggtcaaatgcctggctcccattcgagaccccaagactgagcag
gatgggcacgacattgagaatgagtgcctgggaatggctgtcctagccatctcgcactat
gccatgatgaagaagatgcagttgccagagcttcccaaggacatcagctacaagcgatat
attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata
aataatgttttcaaggatttcctaaaggaatttaacaacaagaccatttgtgacagcagc
gtgtccatgcacgacctgaaggtgaagtacctggccaccttggaaactttgacaaaacat
tatggtgctgaaatatttgagacttccgagttactgatttcatcagaaaatgagatgaat
cgatttcatctgaatgacagtggaaacattctctactatgaagtgatggtgactggaaat
cttggaatccagtggaggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaa
ctgaaacggaaaaaactggaaaataaatacaagaaggatgaggagaaaaacaaaatccgg
gaagagtggaacaatttttcttacttccctgaaattactcacgttgtaatcaaggagtct
gtggtcagcattaataaacaagacaacaaaaaaatggaactgaagctctcttcccacgag
gaggccttgtcctttgtgtccctggtagatggctactttcggctcacggcagacgcccat
cattacctctgcaccgacgtggctcccccgttgatcgtccacaacatacagaatggctgt
cacggtccaatctgcacagaatatgccatcaataaactgcggcaagaaggaggcgaggag
ggcatgtacgtgctgcgctggagctgtaccgactttgacaacatcctcatgaccgtcacc
tgctttgaaaagtctgaggtgctgggtggccagaaacagttcaagaactttcagatcgag
gtgcagaagggctgctacagcctgcatggctcggaccgcagcttccccagcctcggggac
ctcatgagccacctcaagaagcagatcctgcgcacggacaacatcagctttgtgctgaag
cgctgctgccagcctaagccccgagaaatctccaatctgctggtggctactaagaaagcc
caggagtggcagcctgtctaccccatgagccagctgagtttcgatcggatcctcaagaag
gatattgtgcaaggtgagcaccttggcagaggcacgcggacgcacatctactctgggacc
ctagtggactacagggacgacgaaggaaccccggaagagaagcgaataaaagtgatcctc
aaagtcttggatcccagccacagggacatttctctggccttcttcgaggcagccagcatg
atgagacaggtctcccacaaacacatcgtgtacctctatggcgtctgtgtccgagatgtg
gagaatatcatggtggaagagtttgtagagggagggcccctggatctcttcatgcaccgg
aagagtgatgtcctcaccacaccgtggaagtttaacgtcgccaaacagctggccagtgcc
ctgagttacttggaggataaagacttggtccatggaaacgtgtgcactaaaaacctcctc
ctggcccgcgagggcatcgacagtgagtgcggcccgttcatcaagctcagtgaccccggc
atccccatcactgtgctgtccaggcaagagcgtttagagcgaatcccgtggattgccccc
gagtgtgtggatgactccaagaacctgagcgtggccgctgacaagtggagctttgggacc
acgctctgggagatctgctacaacggcgagatccccctgaaggacaagaccctgatcgag
aaagagaggttctatgaaagccggtgcaggccagtgacaccatcttgtaaggagctggct
gacctgatgacccgctgcatgaactatgaccctaatcagaggcccttcttccgagccatc
atgagagacatcaataagctggaggagcagaatccagacattgtttcagaaagaaagcca
gcagctgaagtggatcccacacattttgaaaagcggttcttaaaaaggatccgtgacttg
ggagagggccactttggcaaggtcgagctctgcaggtatgaccctgagggcgacaatact
ggggagcaggtggctgtcaaatccctgaagcctgagagtggaggtaaccacatagctgat
ctgaagaaagagatcgagatcctaaggaacctctaccatgaaaacattgtgaagtacaaa
ggcatctgcacagaggacggaggaaatggtattaagctcatcatggaatttctgccttcc
ggaagccttaaggaatatcttccaaagaataaaaacaaaattaacctcaaacagcagtta
aaatacgccgttcagatttgtaagggcatggactatctgggttctcagcagtacgttcac
cgcgacttagcagcaagaaatgtcctcgttgagagtgagcaccaagtgaaaatcggagac
ttcggtttaaccaaagccatcgagagggataaagagtactacacggtcaaggatgatcgg
gacagccctgtgttctggtatgctccagaatgtttgattcagtgtaaattttacatcgcc
tctgacgtctggtcttttggagtgactctgcacgagctgctcacctactgcgactcggac
tccagtcccatggcgttgttcctgaaaatgataggccccactcatggccagatgacagtg
acgaggctcgtgaacacactgaaagaggggaagcgcctgccttgtccaccccactgtcca
gatgaggtttatcagcttatgagaaaatgctgggagttccagccatccagtcgcaccacc
tttcagaaccttattgagggctttgaagcgcttttaaaataa
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integrated database retrieval system
