Enterobacteriaceae bacterium S05: CUC76_22840
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Entry
CUC76_22840 CDS
T05725
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ebu
Enterobacteriaceae bacterium S05
Pathway
ebu00790
Folate biosynthesis
ebu01100
Metabolic pathways
ebu01240
Biosynthesis of cofactors
Module
ebu_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
ebu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CUC76_22840
Enzymes [BR:
ebu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CUC76_22840
6.3.2.17 tetrahydrofolate synthase
CUC76_22840
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AWB64203
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Position
4565800..4567068
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AA seq
422 aa
AA seq
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MEKDPIPQATSPLATWLSYLEHLHSKTIDLGLARVSEVARQMDIVKPAPFVFTVAGTNGK
GTTCRTLETVLMAAGYKVGVYSSPHLVRYTERVRIQGAELPEAAHTASFAEIEAARGDIS
LTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVDADVAVVTSIALDHTDWLGPD
RESIGREKAGIFRAGKPAVVGEPDMPHTIAEVASEKGALLQRRGVDWGYEVEGETWSFRD
AGGALSRLPLPQVPLPNAATAVAALRASGLAVDDAILRAGIRDAMLPGRFQIISDAPRVI
LDVAHNPHAAAYLAGRLKTLAKTGRVLAVIGMLHDKDIAGTLANLAPEVDAWYCAPLEGP
RGATAEQLVEHLRGGTVYSSVAQAWHAAMADAKVEDTVLVCGSFHTVAQVMEEIDAGRIG
GK
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atggaaaaagatcctattcctcaggccacgtcgcccctggctacgtggctttcttatctg
gaacatctgcacagtaaaaccatcgacctggggctggcgcgcgtcagcgaggtcgcgcgg
cagatggatatcgtcaaaccggcgccgttcgtctttacggtcgcgggtaccaatggcaaa
ggcaccacctgccgcacgctggaaaccgtcctgatggcggccggctataaagtgggggtc
tacagctctccgcatctggtgcgttacaccgaacgcgtgcgcattcagggagcggaactg
ccggaggcggcgcatacggcctcgtttgcggagattgaagcggcgcggggcgacatctcg
ctgacctactttgagtacggcacgctctctgcgctatggttgtttaagcaggcgcagctg
gatgtggtgatcctggaggtggggctcggcggccgtctcgacgccactaatatcgtggat
gccgatgtcgcagtggttaccagcatcgctctcgatcataccgactggctgggaccggat
cgcgaaagtatcggccgggagaaagccggtatcttccgtgccggaaaaccggcggtagta
ggggagccggatatgccgcacaccattgctgaagtggcgagcgagaagggcgccctgctc
cagcgccgcggcgtcgactggggctatgaggtggaaggcgagacatggtctttccgcgac
gcgggcggggcgttaagccgcctgcctctgcctcaggtgccgttgccgaacgccgccacg
gccgtggcggcgctgcgcgccagcggacttgccgtggatgacgcaatcctgcgcgcgggg
atccgcgacgcgatgctgccgggacgctttcagataatcagcgacgccccgcgggtgatc
ctcgatgtggcgcataacccgcacgcggcggcttatctcgccgggcgtctcaaaacgtta
gcgaaaacgggacgcgtgctggcggttattggtatgctgcatgataaggacattgccggc
acgttggccaatctggccccggaagtcgacgcctggtactgcgcgccgctggaagggccg
cgcggggcgacggcggagcagctggtggaacatttgcgtggcggcacagtctatagcagc
gtggcgcaggcgtggcatgcggccatggctgacgctaaagtggaagataccgtgctggtg
tgtggttcgtttcacacggtcgcacaggttatggaagagatagacgcggggagaatcggt
ggcaagtaa
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