Entry Name Flavone and flavonol biosynthesis
Description Flavones and flavonols (3-hydroxyflavones) are common flavonoids in the plant kingdom. They are synthesized as part of the flavonoid modification pathways in aglycone and glucoside forms.
Class Metabolism; Biosynthesis of other secondary metabolitesBRITE hierarchy
Pathway map ec00944 Flavone and flavonol biosynthesis
Ortholog table Enzyme Compound C01155 Quercetin 3,3'-bissulfate
C01156 Quercetin 3,4'-bissulfate
C01265 3,7-Di-O-methylquercetin
C03515 Luteolin 7-O-glucuronide
C03897 Quercetin 3,3',7-trissulfate
C03898 Quercetin 3,4',7-trissulfate
C03951 Luteolin 7-O-beta-D-glucoside
C04024 Vitexin 2''-O-beta-D-glucoside
C04199 Isovitexin 2''-O-beta-D-glucoside
C04444 3,7,4'-Tri-O-methylquercetin
C04608 Apigenin 7-O-beta-D-glucoside
C04858 Apigenin 7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside]
C04900 Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide
C10175 Quercetin 3-(2G-xylosylrutinoside)
C12249 Kaempferol 3-O-glucoside
C12626 Kaempferol-3-O-galactoside
C12627 Apigenin 7-O-neohesperidoside
C12628 Vitexin 2''-O-beta-L-rhamnoside
C12629 Isoswertisin 2''-rhamnoside
C12632 Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]
C12634 Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
C12635 Kaempferol 3-sophorotrioside
C12636 Kaempferol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]
C12637 Quercetin 3-O-[beta-D-xylosyl-(1->2)-beta-D-glucoside]
C12638 Quercetin 3-O-(6-O-malonyl-beta-D-glucoside)
C12667 Quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
C12668 Quercetin 3-sophorotrioside
C16490 Kaempferol 3-O-beta-D-glucosylgalactoside
C19796 Quercetin 3-O-rhamnoside 7-O-glucoside
C21833 Kaempferol-3-O-rutinoside
C21854 Kaempferol 3-O-rhamnoside-7-O-glucoside
Reference Authors De Luca V, Ibrahim RK
Title Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4'-O-methyltransferases.
Journal Reference Authors Jourdan PS, Mansell RL
Title Isolation and partial characterization of three glucosyl transferases involved in the biosynthesis of flavonol triglucosides in Pisum sativum L.
Journal Reference Authors Miller KD, Guyon V, Evans JN, Shuttleworth WA, Taylor LP
Title Purification, cloning, and heterologous expression of a catalytically efficient flavonol 3-O-galactosyltransferase expressed in the male gametophyte of Petunia hybrida.
Journal Reference Authors Cacace S, Schroder G, Wehinger E, Strack D, Schmidt J, Schroder J
Title A flavonol O-methyltransferase from Catharanthus roseus performing two sequential methylations.
Journal Reference Authors Tohge T, Nishiyama Y, Hirai MY, Yano M, Nakajima J, Awazuhara M, Inoue E, Takahashi H, Goodenowe DB, Kitayama M, Noji M, Yamazaki M, Saito K
Title Functional genomics by integrated analysis of metabolome and transcriptome of Arabidopsis plants over-expressing an MYB transcription factor.
Journal Reference Authors Kubo H, Nawa N, Lupsea SA
Title Anthocyaninless1 gene of Arabidopsis thaliana encodes a UDP-glucose:flavonoid-3-O-glucosyltransferase.
Journal Reference Authors Knogge W, Weissenbock G
Title Tissue-distribution of secondary phenolic biosynthesis in developing primary leaves of Avena sativa L.
Journal Reference Authors Anhalt S, Weissenbock G
Title Subcellular localization of luteolin glucuronides and related enzymes in rye mesophyll.
Journal Reference Authors Suzuki H, Nakayama T, Nagae S, Yamaguchi M, Iwashita T, Fukui Y, Nishino T.
Title cDNA cloning and functional characterization of flavonol 3-O-glucoside-6"-O-malonyltransferases from flowers of Verbena hybrida and Lamium purpureum.
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