Equus caballus (horse): 100058245
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Entry
100058245 CDS
T01058
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X12
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb01522
Endocrine resistance
ecb04012
ErbB signaling pathway
ecb04062
Chemokine signaling pathway
ecb04148
Efferocytosis
ecb04151
PI3K-Akt signaling pathway
ecb04360
Axon guidance
ecb04370
VEGF signaling pathway
ecb04510
Focal adhesion
ecb04670
Leukocyte transendothelial migration
ecb04810
Regulation of actin cytoskeleton
ecb04935
Growth hormone synthesis, secretion and action
ecb05100
Bacterial invasion of epithelial cells
ecb05135
Yersinia infection
ecb05146
Amoebiasis
ecb05163
Human cytomegalovirus infection
ecb05165
Human papillomavirus infection
ecb05170
Human immunodeficiency virus 1 infection
ecb05200
Pathways in cancer
ecb05202
Transcriptional misregulation in cancer
ecb05205
Proteoglycans in cancer
ecb05208
Chemical carcinogenesis - reactive oxygen species
ecb05222
Small cell lung cancer
ecb05417
Lipid and atherosclerosis
ecb05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100058245 (PTK2)
04370 VEGF signaling pathway
100058245 (PTK2)
04151 PI3K-Akt signaling pathway
100058245 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100058245 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100058245 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100058245 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
100058245 (PTK2)
04062 Chemokine signaling pathway
100058245 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
100058245 (PTK2)
09158 Development and regeneration
04360 Axon guidance
100058245 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100058245 (PTK2)
05202 Transcriptional misregulation in cancer
100058245 (PTK2)
05205 Proteoglycans in cancer
100058245 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
100058245 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
100058245 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100058245 (PTK2)
05163 Human cytomegalovirus infection
100058245 (PTK2)
05165 Human papillomavirus infection
100058245 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
100058245 (PTK2)
05100 Bacterial invasion of epithelial cells
100058245 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
100058245 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100058245 (PTK2)
05418 Fluid shear stress and atherosclerosis
100058245 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100058245 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100058245 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
ecb01009
]
100058245 (PTK2)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100058245 (PTK2)
Protein kinases [BR:
ecb01001
]
Non-receptor tyrosine kinases
FAK family
100058245 (PTK2)
Protein phosphatases and associated proteins [BR:
ecb01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
100058245 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
100058245
NCBI-ProteinID:
XP_005613371
Ensembl:
ENSECAG00000014150
VGNC:
22002
LinkDB
All DBs
Position
9:complement(81926181..82206030)
Genome browser
AA seq
983 aa
AA seq
DB search
METLLMSGYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQDIALKLGC
LEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFAN
LNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHL
ADFNQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNG
ATQSFIIRPQKEGERALPSIPKLANSERQGVRTHAVSVSGVSHCQHKVKKARRFLPLVFC
SLEPPSTDEISGDETDDYAEIIDEEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQ
FGDVHQGVYLSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITE
NPVWIIMELCTLGELRSFLQVRKYNLDLASLILYAYQLSTALAYLESKRFVHRDIAARNV
LVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCM
WEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL
KAQLSTILEEEKVQQEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPS
PQHMVQTNHYQVSGYPGSHGVTAVAGSIYPAQASLLDQTDSWNHRPQEISMWQPNVEDSA
ALDLRGIGQVLPAHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQ
GPTGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKPWRLQPQEI
SPPPTANLDRSNDRVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVD
ETIPVLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAV
DAKNLLDVIDQARLRMLGQTRPH
NT seq
2952 nt
NT seq
+upstream
nt +downstream
nt
atggagacgctactgatgtcaggatatgaattgagaattcgctatttgccaaaaggattt
ctaaaccagtttactgaagacaagccaactctgaatttcttctatcaacaggtgaagagt
gattatatgttagagatagctgatcaagtggaccaggacattgctttgaagttgggttgt
ctagaaatacggcgatcgtactgggagatgcggggcaatgcactggagaagaagtctaac
tatgaagtgttagaaaaagatgttggtttgaagcggttttttcctaggagtttactggat
tctgtcaaggccaaaacactcagaaaactgatccaacaaacatttagacagtttgccaac
cttaacagagaagaaagtattctgaaattctttgagatcctctccccagtgtacagattt
gataaagaatgcttcaagtgtgctcttggttcaagctggattatttcagtggaactggca
atcggcccggaagaaggcatcagttacctcacggacaagggctgcaacccgacacatctg
gccgacttcaaccaagtgcagaccattcagtattcaaacagcgaggacaaggacaggaaa
ggaatgctgcaactgaaaatagcaggcgcacccgagcctctgacagtgacagcgccatcc
ctcaccatcgcagagaatatggctgacttgatagatggatattgccggctggtgaatgga
gccacgcagtcttttatcatcagaccccagaaagaaggcgaacgggctttgccgtcaata
ccaaagctggccaacagcgagaggcaaggtgtgcggacacacgccgtctccgtgtcagga
gtcagtcactgccagcataaagttaagaaagctaggcgctttctccctttggtcttctgt
tcccttgagcctccttctacggatgaaattagtggggacgaaacagatgattatgctgag
attatagacgaagaagatacttacaccatgccctcaaaaagctatggaatagatgaagct
agggattatgagattcaaagagaaagaatagaacttggacggtgtattggagaaggccaa
tttggagatgtgcaccaaggcgtttatctgagcccagagaatccagctttggcggttgca
attaaaacatgtaaaaactgtacttcggacagcgtgagagagaaattccttcaagaagcc
ttaacgatgcgtcagtttgaccacccgcatattgtgaagctgattggagtcatcacagag
aaccctgtctggatcatcatggagctgtgcacccttggagagctgaggtcatttctacaa
gtaaggaaatacaatttggatctggcgtctttgatcctgtatgcctaccagctaagtaca
gcgctcgcctatctggagagcaaacgctttgtgcacagggacattgctgctcggaatgtt
ctggtgtcctcaaatgattgcgtgaagttaggggactttggattatcccgatacatggaa
gacagcacttactacaaagcttccaaaggaaaattgcctattaaatggatggctccagag
tcaatcaattttcgacgttttacctcagctagtgatgtatggatgtttggtgtatgtatg
tgggagatactgatgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtgatc
ggtcgaattgagaatggggaaagattaccaatgcctccaaattgccctcctaccctctac
agccttatgacgaaatgctgggcctatgaccccagcagacggccccgattcactgagctc
aaagctcagctcagcacaatcctggaagaggagaaggttcagcaagaagaacggatgagg
atggagtccagaagacaggtcacagtgtcctgggactccggagggtccgacgaagcacca
cccaagcccagcagacctggttatcctagtccaaggtccagcgaaggattttaccccagc
ccacagcacatggtgcaaaccaatcattaccaggtctctggctaccctggttcacatgga
gtgacagccgtggctggcagcatctacccagctcaggcatctcttttggaccaaacagat
tcatggaatcatagaccacaggagatatcaatgtggcaacccaacgtggaggactcagcg
gctctggacctgcgaggaatcgggcaggtgttgccggcccacctgatggaagagcggctc
atccgacagcagcaggagatggaagaagatcaacgctggctggaaaaagaggagagattt
ttgaaacctgacgtgcggctctctcgaggcagcattgacagggaggatggaagtcttcag
ggcccgactggaaaccaacacatttatcagcctgtgggtaaaccagatcctgcggctccg
ccaaagaaaccaccgcgccccggagcccccggtcacctgggcagcctcgccagtctcagc
agccccggggacagttacaacgagggtgtcaagccgtggaggcttcaaccccaggaaatc
agcccgcctcccaccgccaacctggaccgctccaatgacagggtgtacgagaacgtgacg
ggcctggtgaaagctgtcatcgagatgtccagtaagatccagcccgccccaccagaggag
tatgttcccatggtgaaggaagtcggcttggccctgaggacgttactggccactgtggat
gagaccattcccgtcctgccagccagcactcaccgagagattgagatggcccagaagctc
ttgaactccgacctgggcgagctcatcaacaagatgaagctggcacagcagtacgtcatg
accagcctccagcaggagtacaaaaagcaaatgctgactgccgcgcacgccctggccgtg
gatgccaagaacttgctcgatgtcatcgaccaggcgagactgagaatgctcgggcagacg
aggccgcactga
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integrated database retrieval system
