Equus caballus (horse): 100066740
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Entry
100066740 CDS
T01058
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00061
Fatty acid biosynthesis
ecb00620
Pyruvate metabolism
ecb00640
Propanoate metabolism
ecb01100
Metabolic pathways
ecb04152
AMPK signaling pathway
ecb04910
Insulin signaling pathway
ecb04920
Adipocytokine signaling pathway
ecb04922
Glucagon signaling pathway
ecb04931
Insulin resistance
ecb04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100066740 (ACACB)
00640 Propanoate metabolism
100066740 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100066740 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100066740 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100066740 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100066740 (ACACB)
04922 Glucagon signaling pathway
100066740 (ACACB)
04920 Adipocytokine signaling pathway
100066740 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100066740 (ACACB)
04931 Insulin resistance
100066740 (ACACB)
Enzymes [BR:
ecb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100066740 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100066740 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100066740 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Ribonuc_2-5A
Motif
Other DBs
NCBI-GeneID:
100066740
NCBI-ProteinID:
XP_001496980
Ensembl:
ENSECAG00000015548
VGNC:
14962
LinkDB
All DBs
Position
8:complement(14042889..14159054)
Genome browser
AA seq
2453 aa
AA seq
DB search
MTLLLFLSCLILSCLTFSWLKIWGKIMDSKPVTKSKSEVSFSPSQEPFPTSDGSGEPPRE
NGDSSSLPRTSKQAEPASHKGPEDACQQRISQLPSDQNPPRNPLSSNDTSPANATGTEGL
EVPDTNDLSSPARPQGQQATSPSKEDEKQAHIKRQLMTNFILGSFDDNSSDEDPGAGLFR
ESSRKGSRASLGALSLEAALTAGESDTLLPIIRTSMSGLYLVKRGREHRKLDLHRDFTVA
SPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLK
ANAEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLR
KHEIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVQWAEDNLQQGKRISVP
EDVYDQGCVKDVDEGLEAAEKIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIP
GSPVFLMKLAKHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPAVFE
FMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQL
QIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPS
SGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELS
IRGDFRTTVEYLINLLETESFQNNDIDTGWLDHLIAEKVQAEKPDIMLGVVCGALNVADA
LFRTCMTDFLHSLERGQVLPAASLLNTVDVELIYGGVKYVLKVARQSLTMFVLIMNGCHI
EIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRVTIGNKTCVFEKENDPTVLRSPSAGKL
MQYTVEDGAHVEAGSSYAEMEVMKMIMTLNVQESGRVKYVKRPGAVLEAGCVVARLELDD
PSKVHPAEPFTGELPSQQTLPILGEKLHQVFHNVLENLTNVMSGYCLPEPIFSIKLKEWV
QKLMMTLRHPTLPLLELQDIMTSVSGRIPVPVEKLVRRVMAQYASNITSVLCQFPSQQIA
TILDCHAATLQRKADREVFFMNTQSIVQLIQRYRSGTRGYMKTVVLDLLRRYLNVEHHFQ
QAHYDKCVINLRERLKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEELTAI
LNELTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKK
LILSETTIFDVLPTFFYHANKIVCMASLEVYVRRAYIAYELNSLQHRQLPDGTCVVEFQF
MLPSSHPNRVAMPISVSNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEV
ISCFANVPKDTPLFSKALTSLYSEDDSKSHREEPIHILNVALQWADHPEDEELVPIFRTF
VQSKKDILAGCGLRRITFLIAQQKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRM
RNFDLTAVPCANHKMHLYLGAAKVKEGAEVTDHRFFIRAIIRHSDLITKEASFEYLQNEG
ERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKL
RVLQAEVKINIRQTTTDSATPIRLFITNESGYYLDISLYREVTDPRSGNIMFHSFGNKQG
PQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDLPEMFRQALFKLWGSPDKYPKDILTY
TELVLDPQGQLVEMNRLPGGNEVGMVAFKMRFKTREYPEGRDVIVISNDITFRIGSFGLG
EDLLYLRASEMARAEGIPKIYLAANSGARIGLAEEIKHMFQVAWVDPEDPHKGFKYLYLT
PQDYTRISSLNSVHCKHIEEEGESRYVITDIIGKDDGLGVENLRGSGMIAGESSLAYEEI
VTISLVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQI
MHYNGVSHSTVPDDFEGIYTILEWLSYMPKDNRSPVPIILPTDPIDREIEFLPSRAPYNP
RWMLAGRPHPTLKGSWQSGFFDQGSFREIMAPWAQTVVTGRARLGGIPVGVIAVETRMVE
VVVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNQEKLPLMIFANWRGFSGGMK
DMYDQVVKFGAYIVDGLRQYRQPILIYIPPYAELRGGSWVVLDSTINPLCIEMYADKESR
GGVLEPEGTVEIKFRKKDLIKAMRRIDPAYKKLTEQLAMSELSDKDRKDLEGQLKAREDL
LLPIYHQVAVQFADLHDTPGRMLEKGVISDILEWKTSRTFLYWRLRRLLLENQVRQEILR
ASSELSHVHIQSMLRRWFVETEGAVKAYLWDNNQMVVQWLEQHWQVGDGLRSTIRENIKY
LKRDSVLKTIRGLVQENPEVAVDCVVYMSQHISPAERAQIVHLLSTMDSPAST
NT seq
7362 nt
NT seq
+upstream
nt +downstream
nt
atgaccctgcttctttttctatcttgtctgattttatcctgcctgaccttttcctggttg
aaaatctgggggaaaattatggactccaagccggtcaccaagagtaaatcggaagtaagc
ttcagcccaagccaggagccctttcccacctcagatggctcaggggagccaccccgggaa
aacggcgacagcagctctctgccaaggacttctaagcaggctgagccagcctcccacaaa
ggtccagaagacgcctgtcagcaaagaatatcccagctaccctcagaccagaatccccca
agaaaccccctttcctctaatgacacctccccagccaatgcgacagggacagaaggactg
gaggtcccagataccaatgacctgtcctcaccagccaggccccagggccagcaagccaca
agcccctccaaagaagacgagaagcaggcacacatcaagaggcagctaatgaccaacttc
atcctgggctcctttgatgacaactcctctgatgaggaccctggtgctggcttgttccga
gagtcttcccggaagggcagccgggccagcctgggggccctgtccctggaggctgctctg
actgcgggcgagtctgacaccctcctccctattataaggaccagcatgtctggactctac
ctggtgaagaggggccgagaacaccggaagctggacctgcacagagactttactgtggct
tccccggctgagtttgtcacacgctttgggggggatcgggtcattgagaaggtgctcatt
gccaacaatggcatcgccgccgtgaagtgcatgcgttccatccgcaggtgggcctacgag
atgttccgaaatgagagagccatccggtttgtagtcatggtgaccccagaggacctgaag
gccaacgcagagtatatcaagatggcagatcagtatgtccccgtcccgggagggcccaac
aacaacaattatgccaacgtggagctgatcgtggacatcgccaagagaatccccgtgcag
gcggtgtgggctggctggggccatgcttctgaaaaccccaaacttccagagctcctgcgc
aagcacgagattgctttcttaggccctcccagtgaagccatgtgggccctgggagataag
atcgcctccaccatcgtggcccagacgctgcagattcccacgctgccctggagtggaagc
ggtctgacggtgcagtgggcagaagacaatctgcagcaggggaaaagaatcagcgtcccg
gaagacgtttatgaccagggttgtgtgaaggacgtagatgagggcttggaggcggcagag
aaaatcggttttccattgatgatcaaagcttctgaaggtggcggagggaaaggaatccgg
aaggcggagagcgccgaggacttccctatccttttcagacaagtgcagagcgagatcccg
ggctccccggtctttctcatgaagcttgccaagcacgcccgccacctggaggtccagatc
ctcgccgaccagtacgggaacgccgtgtctctgtttgggcgagactgctccatccagcgg
agacatcagaagatcatcgaggaggcgccagccaccatcgccacgccggccgtgttcgag
ttcatggagcagtgtgccgtccgcctggccaagaccgtgggctacgtgagcgcagggacg
gttgagtacctctacagccaggacggcagcttccacttcttggagctgaatccccgcctg
caggtggaacacccctgcacagaaatgatcgctgatgtcaacctgccggccgcccagcta
cagattgccatgggcgtgccactgcaccggctgaaggacatccggcttctgtatggagag
tcaccatggggggtgacacccatttcttttgaaaccccttccaaccctcccctcgcccga
ggccacgtcattgcggccagaatcaccagtgaaaacccagatgaggggtttaagccgagc
tccggaacggtccaggagctgaatttccgcagcagcaagaatgtgtggggttatttcagc
gtggctgctactggtggcctacacgagtttgctgattcccagtttgggcactgcttctcc
tggggagagaaccgggaagaggccatttcgaacatggtggtggctttgaaggaactgtcc
atccggggtgacttcagaaccaccgtggaatatctcattaacctcctggagaccgagagc
tttcagaacaatgacattgacactgggtggttggatcacctcatcgctgagaaagtacag
gctgagaagccagatatcatgcttggggtggtgtgcggagccttgaatgtggccgacgcg
ctgttcagaacgtgcatgacggatttcttacactcgctggaaaggggccaggtcctcccc
gcagcttctctgctgaacaccgtggacgtggaattaatttacggaggcgtcaagtacgtg
ctcaaggtggcccggcagtctctgaccatgttcgtcctcatcatgaacggctgtcacatc
gagattgacgcccaccggctgaacgatggtgggctgctgctgtcctacaacggtaacagc
tacacgacctacatgaaagaagaggtggacagttaccgagtcaccatcggcaacaagaca
tgtgtgtttgagaaggagaatgaccccacggtcctgagatccccctcggctgggaagctg
atgcagtacaccgtggaggatggggcccacgtcgaggctggaagcagctacgctgagatg
gaggtgatgaagatgatcatgaccttgaacgtgcaggaaagtggccgggtgaagtacgtc
aagcgcccaggggccgtgctggaagcgggctgtgtggtggccaggctggagctcgatgac
ccttctaaagtgcacccggccgagccgttcacaggggagctcccctcccagcaaactctg
cccatcctcggagagaaactgcaccaggttttccacaacgtcctagaaaacctgaccaac
gtcatgagcggctactgtctgcctgagcctatttttagcataaagctgaaggagtgggtg
cagaagctcatgatgaccctccggcacccaacgctgccgctgctggagctgcaggacatc
atgaccagcgtgtcgggccgcatccctgtccccgtggagaagttggtccgcagggtgatg
gcccagtatgccagcaacatcacctcggtgctgtgccagttccccagccagcagatcgcc
accatcctggactgccacgcggccaccctgcagcggaaggccgaccgggaggtctttttc
atgaacacccagagcatcgtgcagctgatccagaggtaccgcagcgggacccgtggctat
atgaagaccgtggtgttggatctcctgcgaagatatttaaacgtcgagcaccatttccaa
caagcccactacgacaagtgtgtcataaacctcagggagcggctgaagccagacatgtcg
caggtgctggactgcatcttctcccacgcgcaggtggccaagaagaaccagctggtgatc
atgttgatcgacgagctctgtggcccagacccgtccctgtccgaggagctgaccgccatc
ctcaatgagctcactcagctgagcaagagcgagcactgcaaagtggccctcagagccaga
caggtcctgattgcctcccacctgccctcctacgagctgaggcacaaccaggtggagtcc
attttcctgtctgccattgacatgtacggccaccagttctgcccggagaacctcaagaaa
ttaatactttcggaaacaaccatttttgacgtcctgcccactttcttctatcatgctaac
aaaatcgtttgcatggcgtccttggaggtttacgtgcggagggcctacattgcctatgag
ttaaacagcctgcagcaccggcagctcccggacggcacctgcgtggtggaattccagttc
atgctgccctcctcccacccaaaccgggtggccatgcccatcagtgtctccaaccccgac
ctgctgaggcacagcaccgagcttttcatggacagtggcttctcccctctgtgccagcgg
atgggggccatggtcgccttcaggagattcgaggacttcaccagaaactttgatgaagtc
atctcctgcttcgccaacgtgcccaaggacacgcccctcttcagcaaggccctcacttcc
ctgtactccgaggacgacagcaagagccacagagaagagccaatccacatcctgaacgtg
gcccttcagtgggcggaccatccggaggatgaggagctggtgccgattttccggacgttt
gtgcagtccaagaaagacatcctcgcgggttgtggactccgaagaatcacattcctgatt
gcccagcagaaagaatttcccaagtttttcacattcagagcaagagatgagttcgcagaa
gatcgcatttaccggcacctggagcccgccctggccttccagctggagctcagccggatg
cgcaacttcgatctgaccgccgtgccctgtgccaaccacaagatgcacctctacctgggc
gctgcgaaggtgaaggagggcgcggaggtgacggaccacaggttcttcatccgcgccatc
atcaggcactcggacctgatcacgaaggaagcgtccttcgagtacctgcagaatgagggt
gagcggctgctcctggaggccatggacgagctggaggtggccttcaacaacaccagcgtg
cgcaccgactgcaaccacatcttcctcaacttcgtgcccaccgtcatcatggacccctcc
aagatcgaggagtcggtgcgctccatggtgatgcgctacggcagccggctgtggaagctc
cgcgtgctgcaggctgaggtcaagatcaacatccgccagaccaccaccgacagtgcgact
cccatccgcctgttcatcaccaacgagtcaggctactacctggacatcagcctctacaga
gaagtcactgaccccagatctggaaacatcatgtttcactcctttggcaacaaacaaggg
ccccagcacgggatgctgatcaacactccatacgtcaccaaggacctgcttcaggccaag
cgattccaggctcagtccctggggaccacctacgtgtacgacctcccggagatgttcagg
caggctctctttaagctgtggggctccccagacaagtatcccaaagacatcctgacatac
accgaactagtgctggaccctcagggccagctggtggagatgaaccgacttcctggagga
aacgaggtgggcatggtggccttcaaaatgaggtttaagacgcgagagtatccagaaggg
cgggacgtgattgtcatcagcaacgacattaccttccgcatcggctcctttgggctggga
gaagaccttctgtacctgcgggcgtccgagatggcccgggcagagggcatccccaagatc
tacctggcagccaacagcggggcccggatcggccttgcagaggagatcaaacacatgttc
caggtggcgtgggtggacccagaagacccccacaaaggattcaaatacctgtacctgacc
ccccaagactacacccgaatcagctccctgaactccgtccattgtaaacacatcgaggaa
gaaggagaatccaggtacgtcatcacggatatcattgggaaggacgacggcctgggcgtg
gagaacctgaggggctcgggcatgattgccggggagtcctccctggcttacgaagagatc
gtcaccatcagcttggtgacctgccgagcccttgggatcggggcctacttggtgaggctg
ggccagcgagtgatccaggtggagaactcccacatcatcctgacgggagcaagcgctctc
aacaaggtcctgggcagagaggtttacacgtccaacaaccagctgggtggcgtgcagatc
atgcattacaatggcgtctcccacagcaccgtgccagatgacttcgagggcatttatacg
atcctggagtggctgtcctatatgccaaaggataaccgcagccccgtccctatcattctg
cccactgaccccattgacagagagatcgaattcctcccgtccagagctccctacaacccc
cggtggatgcttgcgggaaggcctcacccaactctgaagggatcctggcagagtggattc
ttcgaccagggcagtttcagggaaatcatggcgccctgggcccagactgtggtgacggga
cgagcaaggctggggggcattcccgtcggagtgatcgctgtggagacgcggatggtggag
gtggtggtgcctgcagaccctgccaacctggattccgaggccaagataatccagcaggcg
ggccaggtgtggttcccagactcggcctacaagaccgcccaggccatcaaggatttcaac
caggagaagttgcccctgatgatctttgccaactggaggggcttctccggtggcatgaaa
gacatgtacgaccaggtggtgaagtttggcgcctacatcgtggacggcctcaggcagtac
agacagcccatcctcatctatatcccgccctacgcggagctccggggaggctcctgggtg
gtcctggactccaccatcaaccccctgtgcatagagatgtacgcggacaaagagagcagg
gggggtgttctggagccggagggaacagtggagattaagttccgaaagaaagatctgata
aaggccatgagaaggatcgacccagcttacaagaagctcacggaacagctagcaatgtcc
gagctctccgacaaggaccgcaaagacctggaggggcagctgaaggcccgggaggacctg
ctgctgcccatctaccaccaggtggcagtgcagtttgccgacctccacgacacgccgggt
aggatgctggagaagggcgtcatctcggacatcctggagtggaagacctcacgcaccttc
ctgtactggcgtctgcgccgcctcctgctggagaaccaggtcaggcaggagatcctgcgg
gccagcagcgagctgagccacgtgcacatccagtccatgttgcgccgctggttcgtggag
acggagggggcagtcaaggcctacctgtgggacaacaaccagatggtggtacagtggctg
gagcagcactggcaggtgggcgacggcctgcgttccaccatccgcgagaacatcaagtac
ctgaagcgagactctgtcctcaagaccatccgaggcctcgttcaggaaaaccccgaggtg
gctgtggactgcgtggtgtacatgagccagcacatcagcccggctgagcgggcccagatc
gttcacctcctgtccaccatggacagcccagcctccacctga
DBGET
integrated database retrieval system
