Equus caballus (horse): 100146139
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Entry
100146139 CDS
T01058
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X1
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb04064
NF-kappa B signaling pathway
ecb04380
Osteoclast differentiation
ecb04650
Natural killer cell mediated cytotoxicity
ecb04658
Th1 and Th2 cell differentiation
ecb04659
Th17 cell differentiation
ecb04660
T cell receptor signaling pathway
ecb05135
Yersinia infection
ecb05166
Human T-cell leukemia virus 1 infection
ecb05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ecb05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
100146139 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100146139 (LCK)
04660 T cell receptor signaling pathway
100146139 (LCK)
04658 Th1 and Th2 cell differentiation
100146139 (LCK)
04659 Th17 cell differentiation
100146139 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
100146139 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100146139 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100146139 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
100146139 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
100146139 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100146139 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ecb03036
]
100146139 (LCK)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100146139 (LCK)
Protein kinases [BR:
ecb01001
]
Non-receptor tyrosine kinases
SRC family
100146139 (LCK)
Chromosome and associated proteins [BR:
ecb03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
100146139 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
Haspin_kinase
Kdo
SH3_16
SH3_3
Motif
Other DBs
NCBI-GeneID:
100146139
NCBI-ProteinID:
XP_023490129
Ensembl:
ENSECAG00000023256
VGNC:
19607
LinkDB
All DBs
Position
2:complement(24528171..24548419)
Genome browser
AA seq
533 aa
AA seq
DB search
MGNLSDCSPLCPQNSIRAWHLRGTMGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKATL
PMRNGSEVRDPLVTYEGSNPPASPLQDNLVIALHRYEPSHDGDLGFEKGEQLRILEQSGE
WWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRES
ESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDKGGFYISPRITFPGLHELVRHYTNASDGL
CTRLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLK
QGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTSTGIKL
TINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTA
REGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERG
YRMVRPDNCPEELYQLMMLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
atggggaacctctctgactgctcacctctgtgtccccagaactccatcagagcctggcac
ctaagagggaccatgggctgtagctgcagctcaaaccccgaagatgactggatggaaaac
atcgatgtatgtgagaactgccattaccccatagtcccactggatggcaaggccacgctg
cctatgcggaatggctctgaggtgcgggatccactggtaacctatgagggctccaacccc
ccagcctcccctctgcaagacaacctggttatcgccctgcacagatacgagccctcccac
gatggagacctgggcttcgagaagggcgaacagctccgtatcctggagcagagcggcgag
tggtggaaggcacagtccctgaccacgggccaggaaggtttcatccccttcaacttcgtg
gccaaagcgaacagcctggagcccgaaccctggttcttcaagaacctgagccgcaaggac
gcggaacggcagctcctggcgcccgggaacacgcacggctccttcctgatccgggagagc
gagagtaccgcgggatcgttttcactgtccgtccgggacttcgaccagaaccagggagag
gtggtgaaacattacaagatccgtaacctggacaagggtggcttctacatctccccccgc
atcacctttcccggcctgcatgagctggtccgccattacaccaatgcttcggatgggctg
tgcacgcggttgagccgcccctgccagacccagaagccccagaagccatggtgggaggac
gagtgggaggttcccagggagacgctgaagttggtggagcggctgggggctggccagttc
ggggaggtgtggatgggatactacaacgggcacacgaaggtggcagtgaagagcctgaag
cagggcagcatgtcccccgatgccttcctggcagaggccaacctcatgaagcagctgcaa
caccagcggctggtccggctctacgcggtggtcacccaggagcccatctacatcatcacg
gaatacatggagaacgggagcctggtggattttctcaagacctccacaggcatcaagctg
accatcaacaaactcctggacatggcagcccaaattgcagagggtatggcattcattgaa
gagcggaattatatccaccgtgacctgagggctgccaacatcctggtgtctgacaccctg
agctgcaagatcgcagactttggcctagcacgcctcattgaggacaacgagtacacagcc
agggagggggccaagtttcccattaagtggacagcaccagaagccattaactatgggaca
ttcaccatcaagtcggatgtgtggtcttttgggatcctgctgacggagattgtcacccat
ggccgcatcccttacccagggatgaccaatcctgaggtgattcagaacctggagcgaggt
taccgcatggtgcgacctgacaactgtccagaggagctgtaccaactcatgatgctgtgc
tggaaggaacgcccagaggaccggcccacctttgactacctgcgcagtgtgctggaggac
ttcttcacggccacagagggccagtaccagccccagccctga
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