Escherichia coli O6 K2 H1 CFT073 (UPEC): c0147
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Entry
c0147 CDS
T00106
Symbol
acnB
Name
(GenBank) Aconitate hydratase 2
KO
K01682
aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:
4.2.1.3
4.2.1.99
]
Organism
ecc
Escherichia coli O6:K2:H1 CFT073 (UPEC)
Pathway
ecc00020
Citrate cycle (TCA cycle)
ecc00630
Glyoxylate and dicarboxylate metabolism
ecc00640
Propanoate metabolism
ecc01100
Metabolic pathways
ecc01110
Biosynthesis of secondary metabolites
ecc01120
Microbial metabolism in diverse environments
ecc01200
Carbon metabolism
ecc01210
2-Oxocarboxylic acid metabolism
ecc01230
Biosynthesis of amino acids
Module
ecc_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ecc_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
ecc_M00012
Glyoxylate cycle
Brite
KEGG Orthology (KO) [BR:
ecc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
c0147 (acnB)
00630 Glyoxylate and dicarboxylate metabolism
c0147 (acnB)
00640 Propanoate metabolism
c0147 (acnB)
Enzymes [BR:
ecc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.3 aconitate hydratase
c0147 (acnB)
4.2.1.99 2-methylisocitrate dehydratase
c0147 (acnB)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Aconitase_2_N
Aconitase_B_N
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AAN78641
UniProt:
A0A0H2V4N5
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Position
141792..144542
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AA seq
916 aa
AA seq
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MLLFCKQINTSSKSCYSARCGTGHLPYKLLSHRSVKRIACRTMTMRARRTVVLEEYRKHV
AERAAEGIAPKPLDANQMAALVELLKNPPAGEEEFLLDLLTNRVPPGVDEAAYVKAGFLA
AVAKGEAKSPLLTPEKAIELLGTMQGGYNIHPLIDALDDAKLAPIAAKALSHTLLMFDNF
YDVEEKAKAGNEYAKQVMQSWADAEWFLNRPALAEKLTVTVFKVTGETNTDDLSPAPDAW
SRPDIPLHALAMLKNAREGIEPDQPGVVGPIKQIEALQQKGFPLAYVGDVVGTGSSRKSA
TNSVLWFMGDDIPHVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDV
YPYKGEVRNHETGELLATFELKTDVLIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVF
RQAKDVAESDRGFSLAQKMVGRACGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLA
CLGFSADLVMQSFCHTAAYPKPVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLP
DTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDL
VHAIPLYAIKQGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTI
KLNKEPIIEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAV
IDIDLADIKEPILCAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKG
QLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTS
TRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFDQL
SQYTEKADGVIFQTAV
NT seq
2751 nt
NT seq
+upstream
nt +downstream
nt
atgttgcttttttgtaaacagattaacacatcgtcaaaatcctgctattctgcccgttgc
ggtactgggcatttaccctacaaactgctgtctcacaggagcgtgaagagaatcgcctgc
cgcactatgacaatgagagcgaggagaaccgtcgtgctagaagaataccgtaagcacgta
gctgagcgtgccgctgaggggattgcgcccaaacccctggatgcaaaccaaatggccgca
cttgtagagctgctgaaaaacccgcccgcgggcgaagaagaattcctgttagatctgtta
accaaccgtgttccccctggcgtcgatgaagccgcctatgtcaaagcaggcttcctggct
gctgtcgccaaaggcgaagctaaatccccgctgctgactccggaaaaagccattgaactg
ctgggcactatgcagggtggttacaacattcatccgctgatcgacgcgctggatgatgcc
aaactggcaccgatcgctgccaaagcactttctcacacgctgctgatgttcgataacttc
tatgacgtagaagagaaagccaaagcaggcaacgaatatgcgaagcaggtaatgcagtcc
tgggcggatgccgaatggttcctgaatcgcccggcgctggctgaaaaactgaccgttacc
gtcttcaaagtcactggcgaaaccaacaccgatgacctctctccggcaccagatgcgtgg
tcacgcccggatatcccactgcacgcgctggcgatgctgaaaaacgcccgtgaaggtatt
gagccagatcagcctggtgttgttggcccgatcaaacagattgaagctctgcaacagaaa
ggtttcccgctggcgtacgtcggtgacgttgtgggtacgggttcatcgcgtaaatccgcc
acgaactccgttctgtggtttatgggcgatgatattccacatgtgccgaacaaacgcggc
ggtggtttgtgcctcggcggtaaaattgcaccaatcttttttaacacgatggaagacgcg
ggtgcactgccaatcgaagtcgacgtctctaacctgaacatgggcgacgtaattgacgtt
tacccgtacaaaggtgaagtgcgtaaccacgaaaccggcgaactgctggcaaccttcgaa
ctgaaaaccgacgtgctgattgatgaagtgcgtgctggcggccgtattccgctgattatc
gggcgtggcctgaccaccaaagcgcgtgaagcacttggcctgccgcacagcgatgtgttc
cgtcaggcgaaagatgtcgctgagagcgatcgcggcttctcgctggcgcagaaaatggta
ggccgtgcctgtggcgtgaaaggcattcgtccgggcgcgtactgtgaaccgaaaatgact
tctgtaggttcccaggacaccaccggcccgatgacccgtgatgaactgaaagacctggcg
tgcctgggcttctcggctgacctggtgatgcagtctttctgccacaccgcggcatatccg
aagccagttgacgtgaacacgcaccacacgctgccggacttcattatgaaccgtggcggt
gtgtcgctgcgtccgggggacggcgtcattcactcctggctgaaccgtatgctgctgccg
gataccgtcggtaccggtggtgactcccatacccgtttcccgatcggtatctctttcccg
gcgggttctggtctggtggcatttgcagccgcaacaggcgtaatgccgctggatatgccg
gaatccgttctggtacgcttcaaaggcaaaatgcagccgggtatcaccctgcgcgatctg
gtacacgccattccgctgtatgcaatcaaacaaggtctgctgaccgttgagaagaaaggt
aagaaaaacatcttctctggccgcattctggaaattgaaggtctgccggatctgaaagtt
gagcaggcatttgagctgacagatgcgtctgccgagcgttctgctgccggttgtaccatc
aagctgaacaaagaaccgatcattgaatacctgaactctaacatcgtcctgctgaagtgg
atgatcgcggaaggttacggcgatcgtcgtaccctggagcgtcgtattcagggcatggaa
aaatggctggcgaatcctgagctgctggaagccgatgcagatgcggaatacgcggcagtg
atcgacatcgatctggcggatatcaaagagccaatcctctgtgcaccgaatgacccggac
gacgcacgtccgctgtctgcggtacagggcgagaagattgacgaagtatttatcggttct
tgcatgactaacatcggtcacttccgtgccgctggtaaactgctggatgcgcacaaaggt
cagttgccgacccgcctgtgggtggcaccgccaacgcgtatggacgctgcgcagctgacc
gaagaaggctactacagcgtcttcggtaagagtggtgctcgtatcgagatccctggctgt
tccctgtgtatgggtaaccaggcgcgtgtagcagacggtgcgacggtggtttccacctct
acccgtaacttcccgaaccgtttgggtactggcgcgaatgtcttcctggcttctgcggaa
ctggctgctgttgcggcgctgattggcaaactgccgacgccggaagagtaccagacctac
gtggcgcaggtagataaaacagccgttgatacttaccgttatctgaacttcgaccagctt
tctcagtacaccgaaaaagcggacggggtgattttccagactgcggtttaa
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