KEGG   Escherichia coli O127 H6 E2348/69 (EPEC): E2348C_3805
Entry
E2348C_3805       CDS       T00796                                 
Symbol
ghrB
Name
(GenBank) 2-keto-D-gluconate reductase (glyoxalatereductase) (2-ketoaldonate reductase)
  KO
K00090  glyoxylate/hydroxypyruvate/2-ketogluconate reductase [EC:1.1.1.79 1.1.1.81 1.1.1.215]
Organism
ecg  Escherichia coli O127:H6 E2348/69 (EPEC)
Pathway
ecg00030  Pentose phosphate pathway
ecg00260  Glycine, serine and threonine metabolism
ecg00620  Pyruvate metabolism
ecg00630  Glyoxylate and dicarboxylate metabolism
ecg01100  Metabolic pathways
ecg01110  Biosynthesis of secondary metabolites
ecg01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ecg00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00030 Pentose phosphate pathway
    E2348C_3805 (ghrB)
   00620 Pyruvate metabolism
    E2348C_3805 (ghrB)
   00630 Glyoxylate and dicarboxylate metabolism
    E2348C_3805 (ghrB)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    E2348C_3805 (ghrB)
Enzymes [BR:ecg01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.79  glyoxylate reductase (NADP+)
     E2348C_3805 (ghrB)
    1.1.1.81  hydroxypyruvate reductase
     E2348C_3805 (ghrB)
    1.1.1.215  gluconate 2-dehydrogenase
     E2348C_3805 (ghrB)
SSDB
Motif
Pfam: 2-Hacid_dh_C 2-Hacid_dh NAD_binding_2 GFO_IDH_MocA
Other DBs
NCBI-ProteinID: CAS11353
UniProt: B7ULB4
LinkDB
Position
3971192..3972166
AA seq 324 aa
MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGSNENVDAAL
LEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVE
VAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHH
KEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPV
VDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAAC
AVDNLIDALQGKVEKNCVNPHVAD
NT seq 975 nt   +upstreamnt  +downstreamnt
atgaagccgtccgttatcctctacaaagccttacctgatgatttactgcaacgcctgcaa
gaacatttcaccgttcaccaggtggcaaacctcagcccacaaaccgtcgaacaaaatgca
gcaatttttgccgaagcagaaggcttgctgggttcaaacgagaatgttgatgccgcattg
ctggaaaaaatgccgaaactgcgtgccacatcaacgatctccgtcggctatgacaatttt
gatgtcgatgcgcttaccgcccgaaaaattctgctgatgcacacaccaaccgtattaaca
gaaaccgtcgccgatacgctgatggcgctggtgttgtctaccgctcgtcgggttgtggag
gtagcagaacgggtaaaagcaggcgaatggaccgcgagcataggcccggactggtacggc
actgacgttcaccataaaacactgggcattgtcgggatgggacggatcggcatggcgctg
gcacaacgtgcgcactttggcttcaatatgcccatcctctataacgcgcgccgccaccat
aaagaagcagaagaacgcttcaacgcccgctactgcgatttggatacactgttacaagag
tcagatttcgtttgcctgatcctgccgttaactgatgaaacgcatcatctgtttggcgca
gaacaattcgccaaaatgaaatcctccgccattttcattaatgccggacgtggcccggtg
gttgatgaaaatgcactgattgctgcattgcagaaaggggaaattcacgccgccgggctg
gatgtcttcgaacaagagccactgtccgtagattcgccgttgctctcaatggccaacgtc
gtcgcagtaccgcatattggatctgccactcatgagacgcgttatggcatggccgcctgt
gccgtggataatttgattgatgcgttacaaggaaaggttgagaagaactgtgtgaatccg
cacgtcgcggactaa

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