Escherichia coli O127 H6 E2348/69 (EPEC): E2348C_4158
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Entry
E2348C_4158 CDS
T00796
Symbol
fadB
Name
(GenBank) fused 3-hydroxybutyryl-CoAepimerase/delta(3)-cis-delta(2)-trans-enoyl-CoAisomerase/enoyl-CoA hydratase/3-hydroxyacyl-CoAdehydrogenase
KO
K01825
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:
1.1.1.35
4.2.1.17
5.1.2.3
5.3.3.8
]
Organism
ecg
Escherichia coli O127:H6 E2348/69 (EPEC)
Pathway
ecg00071
Fatty acid degradation
ecg00280
Valine, leucine and isoleucine degradation
ecg00310
Lysine degradation
ecg00362
Benzoate degradation
ecg00380
Tryptophan metabolism
ecg00410
beta-Alanine metabolism
ecg00640
Propanoate metabolism
ecg00650
Butanoate metabolism
ecg00907
Pinene, camphor and geraniol degradation
ecg00930
Caprolactam degradation
ecg01100
Metabolic pathways
ecg01110
Biosynthesis of secondary metabolites
ecg01120
Microbial metabolism in diverse environments
ecg01200
Carbon metabolism
ecg01212
Fatty acid metabolism
Module
ecg_M00087
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:
ecg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
E2348C_4158 (fadB)
00650 Butanoate metabolism
E2348C_4158 (fadB)
09103 Lipid metabolism
00071 Fatty acid degradation
E2348C_4158 (fadB)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
E2348C_4158 (fadB)
00310 Lysine degradation
E2348C_4158 (fadB)
00380 Tryptophan metabolism
E2348C_4158 (fadB)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
E2348C_4158 (fadB)
09109 Metabolism of terpenoids and polyketides
00907 Pinene, camphor and geraniol degradation
E2348C_4158 (fadB)
09111 Xenobiotics biodegradation and metabolism
00362 Benzoate degradation
E2348C_4158 (fadB)
00930 Caprolactam degradation
E2348C_4158 (fadB)
Enzymes [BR:
ecg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
E2348C_4158 (fadB)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.17 enoyl-CoA hydratase
E2348C_4158 (fadB)
5. Isomerases
5.1 Racemases and epimerases
5.1.2 Acting on hydroxy acids and derivatives
5.1.2.3 3-hydroxybutyryl-CoA epimerase
E2348C_4158 (fadB)
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.8 Delta3-Delta2-enoyl-CoA isomerase
E2348C_4158 (fadB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
3HCDH_N
ECH_1
3HCDH
ECH_2
ETF
Motif
Other DBs
NCBI-ProteinID:
CAS11706
UniProt:
B7UNH4
LinkDB
All DBs
Position
complement(4345059..4347248)
Genome browser
AA seq
729 aa
AA seq
DB search
MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSN
KAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCEC
VLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALK
IGLVDGVVKAEKLVEGAMAILRQAINGDLDWKAKRQPKLEPLKLSKIEAAMSFTIAKGMV
AQTAGKHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVK
GKAKKLTKDVETPKQAAVLGTGIMGGGIAYQSAWKDVPVVMKDINDKSLTLGMTEAAKLL
NKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDVVVEAVVENPKVKKAVLAETEQKVRP
DTVLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAW
ASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYL
LDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFNANRFGQKNGLGFWRYKEDSKGKP
KKEEDAAVDDLLAEVSQPKRDFSEEEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVY
GLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPA
RPVGDLKTA
NT seq
2190 nt
NT seq
+upstream
nt +downstream
nt
atgctttacaaaggcgacaccctgtaccttgactggctggaagatggcattgccgaactg
gtatttgatgccccaggttcagttaataaactcgacactgccaccgtcgccagcctcggc
gaggccatcggcgtgctggaacagcaatcagatctaaaagggctgctgctgcgttcgaac
aaagcagcctttatcgtcggtgctgatatcaccgaatttttgtccctgttcctcgttcct
gaagaacagttaagtcagtggctgcactttgccaatagcgtgtttaatcgcctggaagat
ctcccggtgccgaccattgctgccgtcaacggctatgcgctgggcggtggctgcgaatgc
gtgctggcgaccgattatcgtctggcgacgccggatctgcgcatcggtctgccggaaacc
aaactgggcatcatgccgggctttggcggttctgtacgtatgccacgtatgctcggtgct
gacagtgcgctggaaatcattgccgccggtaaagatgtcggcgcggatcaggcgctgaaa
atcggtctggtggatggtgtagtcaaagcagaaaaactggttgaaggggcgatggcgatt
ttacgccaggccattaacggcgacctcgactggaaagcaaaacgtcagccgaagctggaa
ccgctaaaactgagcaagattgaagccgccatgagcttcaccatcgctaaagggatggtc
gcgcaaacggcggggaaacattatccggcccccatcaccgcagtaaaaaccattgaagcg
gcggcccgttttggtcgtgaagaagccttaaacctggaaaacaaaagttttgtcccgctg
gcgcataccaacgaagcccgcgcactggtcggcattttccttaacgatcaatatgtaaaa
ggtaaagcgaagaaactcaccaaagatgttgaaaccccgaaacaggccgctgtgctgggc
acaggcattatgggcggcggcatcgcctaccagtctgcgtggaaagacgtgccggttgtc
atgaaagatatcaacgacaagtcgttaaccctcggcatgaccgaagccgcgaaactgctg
aacaagcagcttgagcgcggcaagatcgatggtctgaaactggctggcgtgatctccaca
attcacccaacgctcgactacgccgggtttgaccgcgtggatgttgtggtagaagcggtt
gttgaaaacccgaaagtgaaaaaagccgtgctggcagaaaccgagcagaaagtacgcccg
gataccgtgctggcgtctaacacttcaaccattcctatcagcgaactggccaacgcgctg
gaacgtccggaaaacttctgcgggatgcacttctttaacccggtgcaccggatgccgttg
gtggaaattattcgcggcgagaaaagctccgacgaaaccatcgcgaaagtcgtcgcctgg
gcgagcaagatgggcaagacgccgattgtggtcaacgactgccccggcttcttcgtcaac
cgtgtactgttcccctatttcgccggtttcagccagttgctgcgcgacggcgcggatttc
cgcaagatcgacaaagtgatggaaaaacagtttggctggccgatgggtccggcatatctg
ctggatgttgtgggcattgacaccgcacatcatgcccaggcagtcatggcagcaggcttc
ccgcagcggatgcagaaagattatcgcgatgccatcgacgcgctgtttaatgccaaccgc
tttggtcagaagaacggcctcggtttctggcgttataaagaagacagcaaaggtaagccg
aagaaagaagaagacgccgctgttgacgacctgctggcagaagtgagccagccgaagcgc
gatttcagcgaagaagagattatcgcccgcatgatgatcccgatggtcaacgaagtggtc
cgctgtctggaagagggcattatcgccactccggcagaagcggatatggcgctggtctac
ggcctgggcttccctccgttccacggcggcgcgttccgctggctggacaccctcggcagc
gcaaaatacctcgatatggcacagcaatatcagcacctcggcccgctgtatgaagtaccg
gaaggtctgcgtaataaagcacgtcataacgaaccgtactatcccccggttgagccagcc
cgtccggttggcgacctgaaaacggcttaa
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