Escherichia coli K-12 W3110: JW1390
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Entry
JW1390 CDS
T00068
Symbol
paaH
Name
(GenBank) 3-hydroxybutyryl-CoA dehydrogenase
KO
K00074
3-hydroxybutyryl-CoA dehydrogenase [EC:
1.1.1.157
]
Organism
ecj
Escherichia coli K-12 W3110
Pathway
ecj00360
Phenylalanine metabolism
ecj00362
Benzoate degradation
ecj00650
Butanoate metabolism
ecj01100
Metabolic pathways
ecj01120
Microbial metabolism in diverse environments
ecj01200
Carbon metabolism
Module
ecj_M00878
Phenylacetate degradation, phenylaxetate => acetyl-CoA/succinyl-CoA
Brite
KEGG Orthology (KO) [BR:
ecj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
JW1390 (paaH)
09105 Amino acid metabolism
00360 Phenylalanine metabolism
JW1390 (paaH)
09111 Xenobiotics biodegradation and metabolism
00362 Benzoate degradation
JW1390 (paaH)
Enzymes [BR:
ecj01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.157 3-hydroxybutyryl-CoA dehydrogenase
JW1390 (paaH)
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Gene cluster
GFIT
Motif
Pfam:
3HCDH_N
3HCDH
3HCDH_RFF
NAD_binding_2
NAD_Gly3P_dh_N
Sacchrp_dh_NADP
DAO
2-Hacid_dh_C
UDPG_MGDP_dh_N
F420_oxidored
Pyr_redox
AlaDh_PNT_C
Pyr_redox_2
TrkA_N
NAD_binding_8
DFP
CbiA
Motif
Other DBs
NCBI-ProteinID:
BAA15001
UniProt:
P76083
Structure
PDB
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All DBs
Position
1460768..1462195
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AA seq
475 aa
AA seq
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MMINVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGK
LTAETCERTLKRLIPVTDIHALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNT
SSISITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQP
VRCHSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLIGQD
VNFAVTCSVFNAFWQERRFLPSLVQQELVIGGRLGKKSGLGVYDWRAEREAVVGLEAVSD
SFSPMKVEKKSDGVTEIDDVLLIETQGETAQALAIRLARPVVVIDKMAGKVVTIAAAAVN
PDSATRKAIYYLQQQGKTVLQIADYPGMLIWRTVAMIINEALDALQKGVASEQDIDTAMR
LGVNYPYGPLAWGAQLGWQRILRLLENLQHHYGEERYRPCSLLRQRALLESGYES
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgatgataaatgtgcaaactgtggcagtgattgggagcggcaccatgggggcaggcatt
gctgaagttgctgccagtcatggacaccaggttttactgtatgacatttctgctgaagcg
ctgacccgcgcaatcgacgggatacacgcgcggctaaattcacgcgtgacgcggggaaaa
ctgactgctgaaacctgtgaacgcacattgaaacgcctgatcccggtgaccgatattcac
gcgctggcagctgcggacctggtcattgaagcggcgtctgaacgtctggaagtcaaaaaa
gcgctctttgcacagctggcggaagtttgcccgccacaaacgctattgaccactaacact
tcgtcaatctctataaccgcgattgctgcggagataaaaaatcctgaacgtgttgcgggg
ctgcatttttttaacccggcaccggtgatgaagttggtggaggtggtcagtgggctggca
acggcggcggaagttgttgagcagttgtgtgaactaacgttgagttggggtaagcagcct
gtgcgctgtcattcgactcctggatttatcgttaaccgtgttgcgcgtccttattattcc
gaggcctggcgggcactggaagagcaggttgctgcaccagaagtgattgacgctgcactt
cgcgatggcgctggtttcccgatggggccgctggaattaaccgatctgattggtcaggac
gtcaattttgctgtcacctgttcggtgtttaacgctttctggcaggagcgtcgtttttta
ccttcgctggtgcaacaggaactggtgattggtggacggttgggcaagaaaagtgggctg
ggcgtgtacgactggcgcgcggaacgtgaggcagttgttggcctggaagcggtaagcgac
agttttagcccaatgaaagtagaaaagaaaagtgacggtgtcacggaaattgacgatgtt
ttattgattgagacacaaggcgagacggcacaggcgctggcaatacgactggcacgcccg
gtggtagtgatcgataaaatggcgggcaaggtggtgaccattgctgctgcagcggtgaac
ccggactcagcgacccgcaaggccatttattacctgcaacagcagggcaaaacagtgctg
caaattgcagattacccaggaatgctgatttggcgaacggtagcaatgatcatcaatgaa
gcccttgatgcgcttcaaaaaggcgtggcctctgaacaggatatcgataccgccatgcgt
cttggggtgaattatccatatggcccacttgcctggggagcgcaacttggctggcagcga
atattaaggctccttgaaaatctacagcatcactatggcgaagaacgctatcgcccatgt
tcattgctgcgccaacgggcgcttctggagagcggttatgagtcataa
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