Escherichia coli O145 H28 RM13516 (EHEC): ECRM13516_3016
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Entry
ECRM13516_3016 CDS
T03011
Symbol
folC
Name
(GenBank) Dihydrofolate synthase / Folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ecoh
Escherichia coli O145:H28 RM13516 (EHEC)
Pathway
ecoh00790
Folate biosynthesis
ecoh01100
Metabolic pathways
ecoh01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
ecoh00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
ECRM13516_3016 (folC)
Enzymes [BR:
ecoh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
ECRM13516_3016 (folC)
6.3.2.17 tetrahydrofolate synthase
ECRM13516_3016 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Methyltransf_2
Motif
Other DBs
NCBI-ProteinID:
AHG15669
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Position
complement(2971626..2972894)
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AA seq
422 aa
AA seq
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MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGVLKPAPFVFTVAGTNGK
GTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGKELPESAHTASFAEIESARGDIS
LTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVDADVAVVTSIALDHTDWLGPD
RESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGALLQRRGVEWNYSVTDHDWAFSD
AHGTLENLPLPLVPQPNAATALAALRASGLEVSENAIRDGIASAILPGRFQIVSESPRVI
FDVAHNPHAAEYLTGCMKALPKNGRVLAVIGMLHDKDIAGTLAWLKSVVDDWYCAPLEGP
RGATAEQLLEHLGNGKSFDSVAQAWDAAMADAKAEDTVLVCGSFHTVAHVMEVIDARRSG
GK
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atgattatcaaacgcactcctcaagccgcgtcgcctctggcttcgtggctttcttatctg
gaaaacctgcacagtaaaactatcgatctcggccttgagcgcgtgagccaggtcgcggcg
cgtcttggcgtcctgaaaccagcgccatttgtatttaccgttgcgggtacgaatggcaaa
ggcaccacctgccgtacgctggagtcgattctgatggcggcagggtacaaagtgggcgtc
tacagttcgccgcatctggtgcgttataccgagcgcgtacgtgtgcagggcaaggaattg
ccggaatcggcccacaccgcctcttttgcggagattgaatcggcacgcggtgatatttcc
ctgacctatttcgagtacggtacgctgtcggcgttgtggctgttcaaacaggcacaactt
gacgtggtgattctggaagtagggctgggcggtcgtctggacgcaaccaatattgtcgac
gccgatgtcgcggtagtaaccagtattgcgctggatcataccgactggctggggccagat
cgcgaaagtattggtcgcgagaaagcaggcatcttccgcagcgaaaaaccggcaattgtc
ggtgagccggaaatgccttctaccattgctgatgtggcgcaggaaaaaggtgcactgtta
caacgtcggggcgttgagtggaactattccgtcaccgatcatgactgggcgtttagcgat
gctcacggcacgctggaaaacctgccgttgccgcttgtcccgcaaccgaatgccgcaacg
gcgctggcggcactgcgtgccagcgggctggaggtcagtgaaaatgccattcgcgacggg
attgccagcgcaattttgccgggacgtttccagattgtgagcgagtcgccacgcgttatt
tttgatgtcgcgcataatccacatgcggcggaatatctcaccgggtgtatgaaagcgcta
ccgaaaaacgggcgcgtgctggcggttatcggtatgctacatgataaagatattgccgga
actctggcctggttgaaaagcgtggttgatgactggtattgtgcgccactggaagggccg
cgcggtgccacggcagaacaactgcttgagcatttgggtaacggcaaatcatttgatagc
gttgcgcaggcatgggatgccgcaatggcggacgctaaagcggaagataccgtgctggtg
tgtggttcgttccacacggtcgcacatgtcatggaagtgattgacgcgaggagaagcggt
ggcaagtaa
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