Escherichia coli LY180: LY180_11995
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Entry
LY180_11995 CDS
T02846
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ecol
Escherichia coli LY180
Pathway
ecol00790
Folate biosynthesis
ecol01100
Metabolic pathways
ecol01240
Biosynthesis of cofactors
Module
ecol_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
ecol00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
LY180_11995
Enzymes [BR:
ecol01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
LY180_11995
6.3.2.17 tetrahydrofolate synthase
LY180_11995
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
16980069
NCBI-ProteinID:
AGW09530
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Position
complement(2523083..2524351)
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AA seq
422 aa
AA seq
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MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGVLKPAPFVFTVAGTNGK
GTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQELPESAHTASFAEIESARGDIS
LTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVDADVAVVTSIALDHTDWLGPD
RESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGALLQRRGVEWNYSVTDHDWAFSD
AHGTLENLPLPLVPQPNAATALAALRASGLEVSENAIRDGIASAILPGRFQIVSESPRVI
FDVAHNPHAAEYLTGRMKALPKNGRVLAVIGMLHDKDIAGTLAWLKSVVDDWYCAPLEGP
RGATAEQLLEHLGNGKSFDSVAQAWDAAMADAKAEDTVLVCGSFHTVAHVMEVIDARRSG
GK
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atgattatcaaacgcactcctcaagccgcgtcgcctctggcttcgtggctttcttatctg
gaaaacctgcacagtaaaactatcgatctcggccttgagcgcgtgagccaggtcgcggcg
cgtcttggcgttctgaaaccagcgccatttgtgtttaccgttgcgggtacgaatggcaaa
ggcaccacctgccgtacgctggagtcgattctgatggcggcagggtacaaagtgggcgtc
tacagttcaccgcatctggtgcgttataccgagcgcgtacgtgtgcagggccaggaattg
ccggaatcggcccacaccgcctcttttgcggagattgaatcggcacgcggtgatatttcc
ctgacctatttcgagtacggtacgctgtcggcgttgtggctgttcaagcaggcacaactt
gacgtggtgattctggaagtagggctgggcggtcgtctggacgcaaccaatattgtcgat
gccgatgtcgcggtagtaaccagtattgcgctggatcataccgactggctgggtccagat
cgcgaaagtattggtcgcgagaaagcaggcatcttccgcagcgaaaaaccggcaattgtc
ggtgagccggaaatgccttctaccattgctgatgtggcacaggaaaaaggtgcactgtta
caacgtcggggcgttgagtggaactattccgtcaccgatcatgactgggcgtttagcgat
gctcacggcacgctggaaaatctgccgttgccgcttgtcccgcaaccgaatgccgcaacg
gcgctggcggcactgcgtgccagcgggctggaagtcagtgaaaatgccattcgcgacggg
attgccagcgcaattttgccgggacgtttccagattgtgagcgagtcgccacgcgttatt
tttgatgtcgcgcataatccacatgcggcggaatatctcaccgggcgtatgaaagcgcta
ccgaaaaacgggcgcgtgctggcggttatcggtatgctacatgataaagatattgccgga
actctggcctggttgaaaagcgtggttgatgactggtattgtgcgccactggaagggccg
cgcggtgccacggcagaacaactgcttgagcatttgggtaacggcaaatcatttgatagc
gttgcgcaggcatgggatgccgcaatggcggacgctaaagcggaagacaccgtgctggtg
tgtggttctttccacactgtcgcacatgtcatggaagtgattgacgcgaggagaagcggt
ggcaagtaa
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