Etheostoma cragini (Arkansas darter): 117949330
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Entry
117949330 CDS
T07493
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
ecra
Etheostoma cragini (Arkansas darter)
Brite
KEGG Orthology (KO) [BR:
ecra00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecra01001
]
117949330 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ecra04131
]
117949330 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ecra04147
]
117949330 (lrrk2)
Enzymes [BR:
ecra01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
117949330 (lrrk2)
Protein kinases [BR:
ecra01001
]
Serine/threonine kinases: TKL group
LRRK family
117949330 (lrrk2)
Membrane trafficking [BR:
ecra04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
117949330 (lrrk2)
Exosome [BR:
ecra04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
117949330 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
Roc
COR
Ras
LRR_9
Arf
NACHT
Ank_3
AAA_22
Ank_2
AAA_16
PduV-EutP
Septin
Viral_helicase1
nSTAND3
G-alpha
T2SSE
GTP_EFTU
cobW
ABC_tran
DLIC
ATP_bind_1
AAA_18
AAA_7
NB-ARC
Rad17
Ank_4
SRPRB
MMR_HSR1
UNC45-central
Motif
Other DBs
NCBI-GeneID:
117949330
NCBI-ProteinID:
XP_034735373
LinkDB
All DBs
Position
8:complement(3996204..4038633)
Genome browser
AA seq
2537 aa
AA seq
DB search
MFNTMVSNEELEERLKKLLVRLKILQEDRQLCTLIQIIEDLLFLAHTDNAAELFEDKDVH
VPLMVVLVSYISSKGVQQVGWSLLCRLIEICPDTLDQLTRPLQAVKDWDVLGVHQQILKV
LSEYRTDCRVTMVGLRALALLLRSDMIPLLVLEEEEDVFGLVVQAMKTFPNSEEVQLQGC
RALQFLLERVSDDHLVEFVENQDHVVVLAALQMFPDSPELHLQAMKVLLPLARPGSNVEM
LMSGGARCYSVIVAAMDTFSEVEELQETACCLFRRFTSESYYNILVLNGVLRVLVKACQS
FPDNVKLQAAALSCLADLTPTIVQNKAVAEQGLEEGEEEENRGREEVEDMGLGWMEVCCT
ALELHAAEPDVQEAASWAIHNLLLHGVKHSEKEQEERTPVYRQLMAAILLHSSSPSVFQA
ATSAIATLLTHNSKMCSALLSSGLHVNLVEMMKRHSTSAEVSVSACRLLSLLFQGRTASL
DELNMAMSQILSSMKVHNFQPEVQLEALQASLVFLCPERSLREHGVSVADPDMADVSLKV
LKNQCVVEGAHTLYLEVLNRFISSSTIQTCGLKVLSALADCSGAVDLLCQQGAIDTVLHT
LQMFPQEREIHFWGLTLLNYLVTKKKLSRMIVPVLANVVVDSLIQYREESEMLLKCFQVA
LRMLDACSGAAAELQREDFDRQIFRHLRETPDQNNNALRKSVCLALSKMWCDSQLHYSML
EKACEDGDTTLAECLIELGADINGKTKTESLIYQVCERGGPLELVELLLSRGAHEQHLRR
ALAVSVKRGEGPTIIQLLGRLGLDLNNSALCLGGFRLGRLDAAWLSPLLTERGRTYSLRC
KNSKGMSLARYIQSLQRSKSLGGPPRSLGGDPCLTSGYISDESDDSSFSFVSMDDSLFDD
LESDGSDSLPGVLSPKPHNNSTEELREGSLKRKQGRRRHASAESGPTEKEHSEHVHRRNG
RTGSSQKVFGFAESSAALPKEKERIRLLDLSGNELDSLSCLMDDGFVQQQLGHLLRLDLS
HNRLLEFPSALCQSLKSLTRLDLQGNQLQSLPAELLSLLSLSMLNVSRNCVGPLLTFDPA
VTCQSLGQLNLSFNKITTFPLELGRAMSQLEELFLEGNSITELCVPPILPEIKLLDVSKN
SVENISPEFLTACPKLETFSASMNTICSLSYLPSKITTLKLANNSFTCVPEAILNLPNLR
SVDMRTNSIGDLPGPGLWESSNLRELMFSHNCIKVLDLSGPTYKWTRLEKLHLSDNKLTE
IPPQIGLLEDLTSLDVSRNTNLRSFPDEMGKLGRLWDLPLDGLRLQLDLKLIGSKTKDIV
RFLQQRLKKAVPYYRMKLIVVGNAGSGKTTLIQQLMKLKRSQLNSKQDAVGINVRDWTIR
ERDKKKMVLNVWDFSGGEEFSGSHPHFLTSRALYLVVYNISKGASQVDALKPWLFNIKAV
APLSPVILVGTHTDTSDELQLQACLTKIREELLNHQGFPAIRDYHMVSVCEDSDAMAKLR
KAIAREVTSFKIQGQPVMGQLVPDNYVELERRVLQERTRVPPEFPVLRHQELLQLIQESQ
LQLEEAELSHAVHFLSEAGLLLHFDDPALQLQDLYFIEPQWLCNIISQKLTLKSGGFWEH
PKGVVQRSVVEKFLFETKCFPKSHMTQFFKLLEKFQIALPFGEDQLLIPSSLSKHRPVIE
LPHCENSEVIVRLYEMPYFPMDYWSRQISRLLEVSSYLLCGGGKAVRPNRIYWRRGVYLS
WSPEAYCLVEENPSSFVRITVPSSRKGQVLLGQVVDHIDSLLEEWFPGLLNTDMHGSGEA
LLKKWALYSFEDGQEWSKILLEDLFTYFDNDFLLVNPKDPRYTLPISQIAPDLVLSDQPA
GTILDSEELDVDMSKENQLGDGGFGTVYRGVYKNEEVAVKIFNKHASELYIYRLLRQELA
VLGRLRHPSLVGLLAAGSVPQVLVMELALRGSLDSLFEHENGSLNLKLQHRIALHVADGL
RYLHAAMIIYRDLKPHNVLLFNLKTDSEIIAKITDYGIAQYCCSMGVRSSEGTPGFRAPE
VARGSVIYNQQADVFSFGLLLYDLLTCGERISDGMKFPSEFDEVAVQGKLQDPVKHYGCS
PWPGFQTLMKDCLRESPQGRPTSAQVFDRLNSGEMLCLMRELVVPRVFNAECFTVSSGSR
DCSSNRHRAWLGGGSSTRRLGSITAVDLDTSTVTTQEIDNSPVLCLVTVQIPTESCDWLV
AGTQSGSLVIISTQDTSIWHHLQSVTDAVTSLYFHVHPYRTQRKNYLLVGTADGVLTVYE
DCVLKQENGQPVKSLTVGNVNTPVMCLGQSVHSLDSRSVWAGCGTKILSFTADYDVCKSI
DTRPNLVFQQARSLGGEACVSRLVVDKYVYLSKAGTPTVEVWDKRSERMVDCINCAQIIR
HDSGGRGRQGSEAELPTDAAPSWARVKALLVQSSATLWIGTRGGHLLLLELSKHQPLQVI
GPVCSSIRCIASALIETLNWKNVVLILGRRQDRNVLGEESVLMVWSGALPMEGKDLNKHC
EKREQIAAKMREQLQHA
NT seq
7614 nt
NT seq
+upstream
nt +downstream
nt
atgtttaacaccatggtaagcaacgaggagttagaagaaaggttgaagaaacttctggtg
aggctgaaaatcctgcaagaagacagacaactgtgcacactaatacaaataattgaggac
ctgcttttcctggcgcacaccgacaatgcagctgagctgtttgaagacaaagatgtccat
gtccccctcatggtggtgctggtgtcctacattagcagcaaaggagtccagcaggtgggt
tggtcattgctgtgtcgtctaattgaaatatgccccgatacgctggaccagctgaccaga
cctctgcaggcagtcaaggactgggatgtactgggagtgcaccagcagatcctgaaagta
ctatcggagtacaggacagactgcagagtgaccatggttggactccgagccctggctctc
ctgctcagatcagacatgattcctttgctggtgctggaggaggaagaggatgtttttggc
ttggtggtgcaggcaatgaagacgtttcctaacagtgaagaggtgcagctccaaggctgt
agagctctccaattcctcctggagagagtaagtgatgaccacctggtggagtttgtggag
aaccaggatcatgtagttgttctggcggctctgcaaatgtttccagacagccccgagctg
cacctgcaggccatgaaggtgctgctcccactggctcgtcctggcagtaacgtggagatg
ttgatgtcgggaggtgctcggtgctacagcgtgatcgtcgccgccatggacacgttctcc
gaggtggaggagttgcaggagacggcctgctgccttttcaggaggtttacatcagagagt
tactacaacatcctggtactgaacggcgtcctgagggtcttggtcaaagcctgtcagtct
ttccctgacaacgtcaagctgcaagctgccgctctctcctgtctggctgacctcacccca
accatcgtacagaacaaagcggtggccgagcagggtctggaggaaggggaggaggaggag
aacaggggtagggaggaggtggaagacatgggcctgggctggatggaggtctgctgtacg
gcactggagctccacgctgccgagccagatgttcaggaagctgcaagctgggccattcac
aatctgttgctgcacggagtgaagcattcagaaaaggaacaggaagagaggactcctgtc
tacagacagttgatggcggccattctgctccactcctcctcccccagtgtgtttcaagct
gctaccagtgccattgccacactcctcacacacaacagtaaaatgtgctctgcgctgctg
tccagtggcctccacgtcaacctagtggagatgatgaagagacattcaacctcagctgaa
gtttcagtcagcgcctgtagactgctcagcctgctcttccagggaaggacagcaagtcta
gatgagttgaacatggccatgagtcagatcctcagcagcatgaaggtccacaacttccag
ccagaggtccagctggaggctctgcaggccagcctggtcttcctctgcccagaaaggagt
ttaagggagcacggagtctcagttgcagatcctgacatggccgacgtgtcactgaaggtg
ctaaaaaaccagtgtgtggtggaaggagctcacaccctctacctggaggttctcaacagg
ttcatcagcagctcgaccatacagacgtgcggtctgaaggtgctgtctgctctggctgac
tgctctggtgcagtggacctgctctgccaacagggggcgatagacacagtgctgcacaca
cttcagatgttcccacaggaacgagagatacacttctggggtctcaccctgctcaactac
ctcgtaaccaagaagaagctgtcgaggatgatcgtacctgttctggccaacgttgtggtc
gactcactcatccagtacagggaagagtctgagatgctcctgaagtgttttcaggtggct
ctaaggatgctggacgcctgttcaggagcagctgctgaactgcagagagaagactttgac
aggcagatcttcagacacctcagagagactcccgaccagaacaacaatgctctgcgtaaa
tcggtgtgcctggctctgtctaagatgtggtgcgactcccagctacactacagcatgctg
gaaaaggcctgtgaggacggagacacgacattggctgagtgtctgatcgagctgggcgcg
gacatcaatggaaaaaccaaaacagaatctctcatctaccaggtgtgtgagagaggcggc
cctctggagctggtggagctcttgctcagccgaggtgcccacgagcagcacctccgcagg
gctcttgctgtgagcgtgaagcggggcgaaggacccacaatcattcagctgctgggtcgt
ctgggtctggacctcaacaacagcgccctctgcctcgggggcttccggctgggccgcctg
gacgccgcctggctcagccccctgctgacagaaagaggcagaacatacagtctccgttgc
aagaacagtaaaggtatgagtttggcgaggtatattcagtctctccagaggtccaagagt
ctcggtggtcctcctagatctctgggcggcgacccgtgtctcacatctggctacatttct
gacgagagcgacgactccagcttcagcttcgtctccatggacgacagtttatttgacgat
ttggagagtgacgggagtgactccctgccaggtgttctgtctccaaagccacacaataat
tcaacagaagagttgagagaagggtctttaaaaaggaagcaaggacgccgcagacatgcc
agtgcagagagtggtccaactgagaaggaacacagcgagcatgtacacaggagaaatgga
aggactggctcaagtcaaaaagtttttggatttgctgagagctccgctgccctgcccaaa
gagaaggaaaggatccgccttctggacctgtcagggaacgagttggactccctgtcctgt
ctgatggatgatggattcgtccagcaacagctggggcatctcctccgtctggacctgagc
cacaacagactgctggagtttccctcagctctttgccagagtttgaagagtctgactcgg
ttggacctgcagggcaaccagctccagtcgctgccagcggagctgctgtctctgctctca
ctgagcatgctgaacgtctcacgtaactgtgtgggtcccctactgacctttgaccctgct
gtcacctgccaatcactggggcagctcaatctttctttcaacaaaatcaccacgttccct
ctcgagctgggccgtgccatgagtcaactggaggagctgtttctggaaggtaacagtata
actgagctttgtgtgcctccaattctgcccgagatcaagctgctcgatgtgagcaagaac
agcgtggagaatatttctccagagttcctgaccgcgtgccccaaactagaaactttcagt
gcctccatgaacacaatctgttccctgtcatatctcccatccaagatcaccacactgaaa
ctagcaaacaacagctttacttgtgttcctgaggcgatccttaatctcccaaacttgcgg
tcagtggacatgagaaccaacagcatcggggatctgcctggcccgggactctgggagtcc
agcaacctcagagagctgatgttcagtcacaactgtatcaaagttctggatctgagtggg
ccgacctacaaatggaccagactggaaaaactccacctgagtgacaacaagctcacagag
atccctccacagatcggcctgttggaagatctgacctccttggacgtgagtcggaacacc
aacctgcggtccttccctgatgagatggggaaactgggcagactgtgggatctgccgctg
gacggccttcgactccagctggacctcaaactcatcggcagcaagaccaaggacatagtc
aggttcctgcagcagcggctgaagaaggcagtgccgtactaccggatgaagctcatcgtg
gtggggaatgctggcagcgggaagaccaccctgatccagcagctgatgaagctgaagcga
tcccagttgaactcgaagcaggatgccgttggcatcaacgtccgggactggaccatcagg
gagcgggacaagaagaaaatggtgctgaacgtctgggacttctcaggtggagaggagttc
agcgggtctcaccctcacttcctgacttccagagctctctacctggtggtatacaacatc
agcaaaggagccagtcaggtggacgcactcaagccatggctcttcaacattaaagccgta
gcccctctgtccccggtcatcctggtaggaacccacacagatacgagtgatgagctgcaa
cttcaggcctgcctgaccaagatcagagaggagctgctgaaccaccagggcttccccgcc
atccgggactaccacatggtctctgtctgcgaagactcggacgccatggccaagctccgc
aaggctatcgccagggaagtcaccagcttcaagatccagggccagcctgtgatgggccag
ttggttccagacaactacgtggagctggagcgccgggttctgcaggagagaaccagggtc
cccccagagttccccgttctcaggcaccaggagctgctgcagctcatccaggagagtcag
ctgcagctggaggaagctgagctgtcccacgctgtccacttcctcagtgaagctgggctt
ttactgcactttgatgatcctgcacttcagcttcaagacctctacttcatcgaaccacag
tggctgtgcaacatcatctcccagaagctgacattaaagagtggtggcttctgggagcat
cctaaaggagttgttcagcgctcagtggtggaaaagtttctgtttgagaccaaatgtttt
cccaagagccacatgacgcagttcttcaaattgctggagaagtttcagatcgctctaccc
tttggtgaggaccagctactgatacccagcagtttgtccaaacacagaccggtgatagag
ctgcctcactgtgagaactcagaggtgattgtgcgtctgtacgagatgccgtacttcccc
atggattactggtctcgccagatcagcagactactggaggtctcttcttatctgctttgt
ggaggaggaaaagcggtgcgaccaaaccggatctactggaggagaggcgtgtacctgagc
tggtccccagaggcctactgtctggtggaggaaaacccttccagcttcgtcaggataact
gtgccctcttcacgcaaaggccaggtgctgctgggtcaggtggtggatcacatcgactcc
ctgctagaggaatggtttcctggcctgctgaacactgacatgcacggcagtggtgaggct
ctcctaaaaaagtgggctctctacagctttgaggacggtcaggagtggagcaagattctg
ctcgaggacctcttcacatattttgacaatgattttctgttggtgaacccgaaggatccc
cgctacacactccccatctctcagatcgcccctgacttggtactgagtgaccaacctgca
gggactatactggacagtgaagagctggatgtagacatgtctaaagagaaccaactgggg
gatggtggctttgggactgtttatcgaggtgtctacaaaaatgaagaagtagctgtgaaa
atattcaacaagcatgcttctgagctttacatctacagactcctcagacaggagttggcg
gtgttgggtcgcctccgtcaccccagcctggtgggtctgctggcagccggctcggttcct
caggtcctggtgatggagctggcactgcgaggctctctggactccctatttgaacatgag
aacgggagcctgaacctaaagctccagcacagaatcgccctgcatgttgccgacggactc
aggtaccttcacgcagccatgatcatatatcgagatctcaagccccacaacgttcttctg
ttcaacctgaagaccgattctgagatcatcgccaagattaccgactatggcatcgctcag
tactgctgcagcatgggagtaaggagctcagagggcacgccaggtttccgagcaccggag
gttgcccgaggcagcgtgatctacaaccagcaggcggatgtgttctcattcggcctgctg
ctctacgacctcctgacctgtggtgagcgcatctctgacggcatgaagttccccagtgag
tttgatgaggttgcagtgcaggggaaactgcaagatccagtgaaacactacggctgctca
ccgtggccgggcttccagacgctgatgaaggactgtttgagggaaagccctcaggggcga
cccacttctgctcaggtgtttgataggctgaattcaggagagatgttgtgcctgatgagg
gagctggtggttccccgggtgttcaacgctgagtgcttcacagtgagctccggcagcagg
gactgctcctccaaccggcacagagcctggctaggaggaggcagcagcacgcggaggcta
ggctccatcacggccgtggacctggacaccagcacagtcactacacaggagatcgacaac
agtcccgttttgtgtcttgtgaccgtccaaataccgaccgagtcctgtgattggttggtg
gcaggcacccaatccggctctttagtaatcatcagcactcaggacacgtcgatttggcac
cacctgcagagtgtcacagacgccgtcacctcactgtacttccatgtacacccttaccgc
acccaaaggaagaattacttgctggttgggacagcggatggagttctcactgtttatgag
gactgcgtactcaagcaagaaaacgggcagccggttaaatctctcactgtgggaaacgtc
aacacgcctgtcatgtgtttgggccagtcggtgcattcgctggacagcaggtcggtgtgg
gccggctgcgggaccaagatcctctccttcaccgccgactacgacgtttgcaagagcatc
gacacgagacccaacctcgtcttccagcaggcgcggtcattgggaggtgaagcgtgtgtg
tctcgattggttgtggataaatatgtttacctgagcaaagccgggacaccaaccgtcgag
gtttgggataagagaagtgagaggatggtggactgcatcaactgtgctcagatcatcaga
catgactcggggggcagaggcaggcagggcagcgaggcggagctgcccactgacgcagct
ccctcctgggccagagtcaaagccctgctggtgcagagctcagcaactctctggatcggc
actagagggggccacctgctgctgctggagctctccaaacaccagccgttgcaggtcatc
ggccctgtctgcagttccatacgctgcatcgcctctgcactcatagaaacactaaactgg
aagaatgtggtgctgattttgggcagaagacaagacagaaatgtcttaggcgaggagtcg
gtgctgatggtgtggagcggcgcgctgccgatggagggcaaagacctgaacaaacactgc
gagaaaagagagcagatcgcagccaaaatgagagagcagctccaacatgcctga
DBGET
integrated database retrieval system
