Escherichia coli O45 K1 H7 S88 (ExPEC): ECS88_0127
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Entry
ECS88_0127 CDS
T00830
Symbol
acnB
Name
(GenBank) bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase
KO
K01682
aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:
4.2.1.3
4.2.1.99
]
Organism
ecz
Escherichia coli O45:K1:H7 S88 (ExPEC)
Pathway
ecz00020
Citrate cycle (TCA cycle)
ecz00630
Glyoxylate and dicarboxylate metabolism
ecz00640
Propanoate metabolism
ecz01100
Metabolic pathways
ecz01110
Biosynthesis of secondary metabolites
ecz01120
Microbial metabolism in diverse environments
ecz01200
Carbon metabolism
ecz01210
2-Oxocarboxylic acid metabolism
ecz01230
Biosynthesis of amino acids
Module
ecz_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ecz_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
ecz_M00012
Glyoxylate cycle
Brite
KEGG Orthology (KO) [BR:
ecz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ECS88_0127 (acnB)
00630 Glyoxylate and dicarboxylate metabolism
ECS88_0127 (acnB)
00640 Propanoate metabolism
ECS88_0127 (acnB)
Enzymes [BR:
ecz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.3 aconitate hydratase
ECS88_0127 (acnB)
4.2.1.99 2-methylisocitrate dehydratase
ECS88_0127 (acnB)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Aconitase_2_N
Aconitase_B_N
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
CAR01492
UniProt:
B7MBA1
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Position
137801..140398
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AA seq
865 aa
AA seq
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MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEFLLDLLTNRVPPGVDEA
AYVKAGFLAAVAKGEAKSPLLTPEKAIELLGTMQGGYNIHPLIDALDDAKLAPIAAKALS
HTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRPALAEKLTVTVFKVTGETNTD
DLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVGPIKQIEALQQKGFPLAYVGDVV
GTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSN
LNMGDVIDVYPYKGEVRNHETGELLATFELKTDVLIDEVRAGGRIPLIIGRGLTTKAREA
LGLPHSDVFRQAKDVAESDRGFSLAQKMVGRACGVKGIRPGAYCEPKMTSVGSQDTTGPM
TRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVNTHHTLPDFIMNRGGVSLRPGDGVIH
SWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKM
QPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQAFELTDASA
ERSAAGCTIKLNKEPIIEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEA
DADAEYAAVIDIDLADIKEPILCAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAA
GKLLDAHKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVA
DGATVVSTSTRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDT
YRYLNFDQLSQYTEKADGVIFQTAV
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
gtgctagaagaataccgtaagcacgtagctgagcgtgccgctgaggggattgcgcccaaa
cccctggatgcaaaccaaatggccgcacttgtagagctgctgaaaaacccgcccgcgggc
gaagaagaattcctgttagatctgttaaccaaccgtgttccccctggcgtcgatgaagcc
gcctatgtcaaagcaggcttcctggctgctgtcgccaaaggcgaagctaaatccccgctg
ctgactccggaaaaagccattgaactgctgggcactatgcagggtggttacaacattcat
ccgctgatcgacgcgctggatgatgccaaactggcaccgatcgctgccaaagcactttct
cacacgctgctgatgttcgataacttctatgacgtagaagagaaagccaaagcaggcaac
gaatatgcgaagcaggtaatgcagtcctgggcggatgccgaatggttcctgaatcgcccg
gcgctggctgaaaaactgaccgttaccgtcttcaaagtcactggcgaaaccaacaccgat
gacctctctccggcaccagatgcgtggtcacgcccggatatcccactgcacgcgctggcg
atgctgaaaaacgcccgtgaaggtattgagccagatcagcctggtgttgttggcccgatc
aaacagattgaagctctgcaacagaaaggtttcccgctggcgtacgtcggtgacgttgtg
ggtacgggttcatcgcgtaaatccgccacgaactccgttctgtggtttatgggcgatgat
attccacatgtgccgaacaaacgcggcggtggtttgtgcctcggcggtaaaattgcacca
atcttttttaacacgatggaagacgcgggtgcactgccaatcgaagtcgacgtctctaac
ctgaacatgggcgacgtaattgacgtttacccgtacaaaggtgaagtgcgtaaccacgaa
accggcgaactgctggcaaccttcgaactgaaaaccgacgtgctgattgatgaagtgcgt
gctggcggccgtattccgctgattatcgggcgtggcctgaccaccaaagcgcgtgaagca
cttggcctgccgcacagcgatgtgttccgtcaggcgaaagatgtcgctgagagcgaccgt
ggcttctcgctggcgcagaaaatggtgggccgagcctgtggcgtgaaaggcattcgtccg
ggcgcgtactgtgaaccgaaaatgacttctgtaggttcccaggacaccaccggcccgatg
acccgtgatgaactgaaagacctggcgtgcctgggcttctcggctgacctggtgatgcag
tctttctgccacaccgcggcgtatccgaagccagttgacgtgaacacgcaccacacgctg
ccggacttcattatgaaccgtggcggtgtgtcgctgcgtccgggtgacggcgtaatccac
tcctggctgaaccgtatgctgctgccggataccgtcggtaccggtggtgactcccatacc
cgtttcccgatcggtatctctttcccggcgggttctggtctggtggcatttgcagccgca
acaggcgtaatgccgctggatatgccagaatccgttctggtgcgcttcaaaggcaaaatg
cagccgggtatcaccctgcgcgatctggtacacgcgatcccgctgtatgcaatcaaacaa
ggtctgctgaccgttgagaagaaaggtaagaaaaacatcttctctggccgcattctggaa
attgaaggtctgccggatctgaaagttgagcaggcatttgagctgaccgatgcgtctgcc
gagcgttctgctgccggttgtaccatcaagctgaacaaagaaccgatcattgaatacctg
aactctaacatcgtcctgctgaagtggatgatcgcggaaggttacggcgatcgtcgtacc
ctggagcgtcgtattcagggcatggaaaaatggctggcgaatcctgagctgctggaagcc
gatgcagatgcggaatacgcggcagtgatcgacatcgatctggcggatatcaaagagcca
atcctctgtgcaccgaatgacccggacgacgcacgtccgctgtctgcggtacagggcgag
aagatcgacgaagtatttatcggttcttgcatgactaacatcggtcacttccgtgctgct
ggtaaactgctggatgcgcacaaaggtcagttgccgacccgcctgtgggtggcaccgcca
acgcgtatggacgctgcgcagctgaccgaagaaggctactacagcgtcttcggtaagagt
ggtgctcgtatcgagatccctggctgttccctgtgtatgggtaaccaggcgcgtgtagca
gacggtgcgacggtggtttccacctctacccgtaacttcccgaaccgtttgggtactggc
gcgaatgtcttcctggcttctgcggaactggctgctgttgcggcgctgattggcaaactg
ccgacgccggaagagtaccagacctacgtggcgcaggtagataaaacagccgttgatact
taccgttatctgaacttcgaccagctttctcagtacaccgaaaaagcggacggggtgatt
ttccagactgcggtttaa
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