Escherichia fergusonii: EFER_0848
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Entry
EFER_0848 CDS
T00811
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase and dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
efe
Escherichia fergusonii
Pathway
efe00790
Folate biosynthesis
efe01100
Metabolic pathways
efe01240
Biosynthesis of cofactors
Module
efe_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
efe00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
EFER_0848 (folC)
Enzymes [BR:
efe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
EFER_0848 (folC)
6.3.2.17 tetrahydrofolate synthase
EFER_0848 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
CAQ88384
UniProt:
B7LLF5
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Position
865062..866330
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AA seq
422 aa
AA seq
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MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGVLKPAPFVFTVAGTNGK
GTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQELPESAHTASFAEIESARGDIS
LTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVDADVAVVTSIALDHTDWLGPD
RESIGREKAGIFRNEKPAIVGEPEMPSTIADVAQEKGALLQRRGIEWNYSVSDNDWTFSD
AYGTLENLPLPLVPQPNAATALAALRASGLEVSENAIRDGIASAILPGRFQIVSESPRVI
FDVAHNPHAAEYLTGRMKALPKNGRVLAVIGMLHDKDIAGTLAWLKSVVDDWYCAPLEGP
RGATAEQLLEHLGNGKSFDSVAQAWDAAMADAKAEDTVLVCGSFHTVAHVMEVIDARRSG
GK
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atgattatcaaacgcactcctcaagccgcgtcgcctctggcttcgtggctttcttatctg
gaaaacctgcacagtaaaactatcgatcttggccttgagcgcgtaagtcaggtcgcggca
cgtcttggcgttctgaaaccagcgccatttgtatttaccgttgcgggtacgaatggcaaa
ggcaccacctgccgtacgctggagtcgattctgatggcggcagggtacaaagtgggcgtc
tacagttcgccgcatctggtgcgttataccgagcgcgttcgtgtgcagggccaggaattg
ccggaatcggcccacacagcctcttttgcggagattgaatcggcacgcggtgatatttcc
ctgacctatttcgagtacggtacgctgtcggcgttgtggctgttcaaacaggcacaacta
gacgtggtgatcctggaagtagggctgggcggacgtctggatgcaaccaatattgtcgat
gctgatgttgcggtggtgaccagcattgcgctggatcataccgactggttggggccagat
cgcgaaagcattggtcgtgagaaagcagggattttccgcaatgaaaaaccggcaattgtc
ggagagcctgaaatgccttctaccattgctgatgtggcgcaggaaaaaggcgcactgcta
caacgtcggggcattgagtggaattattccgtcagcgacaatgactggacgtttagcgat
gcttacggcacgctggaaaatctgccgttgccgcttgtcccgcaaccgaatgccgcaacg
gcgctggcggcactgcgtgccagcgggctggaggtcagtgaaaatgccattcgcgacggg
attgccagcgcaattttgccaggacgtttccagattgtgagcgagtcgccacgcgttatt
tttgatgtcgcgcataatccacatgcggcggaatatctcaccgggcgtatgaaagcgtta
ccgaaaaacgggcgcgtgctggcggttatcggtatgctacatgataaagatattgccgga
actctggcctggttgaaaagcgtggttgatgactggtattgtgcgccactggaagggccg
cgcggtgccacggcagaacaactgcttgagcatttgggtaacggcaaatcatttgatagc
gtggcgcaggcatgggatgccgcaatggcggacgctaaagcggaagataccgtgctggtg
tgtggttcgttccacacggtcgcacatgtcatggaagtgattgacgcgaggagaagcggt
ggcaagtaa
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