Epinephelus fuscoguttatus (brown-marbled grouper): 125888060
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Entry
125888060 CDS
T08419
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
efo
Epinephelus fuscoguttatus (brown-marbled grouper)
Brite
KEGG Orthology (KO) [BR:
efo00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
efo01001
]
125888060 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
efo04131
]
125888060 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
efo04147
]
125888060 (lrrk2)
Enzymes [BR:
efo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
125888060 (lrrk2)
Protein kinases [BR:
efo01001
]
Serine/threonine kinases: TKL group
LRRK family
125888060 (lrrk2)
Membrane trafficking [BR:
efo04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
125888060 (lrrk2)
Exosome [BR:
efo04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
125888060 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
Roc
COR
Ras
LRR_9
Arf
AAA_22
NACHT
PduV-EutP
AAA_16
Septin
Viral_helicase1
nSTAND3
Ank_2
G-alpha
UNC45-central
TFCD_C
ATP_bind_1
Rad17
MMR_HSR1
DLIC
SRPRB
cobW
ABC_tran
T2SSE
AAA_18
AAA_7
Arm
TsaE
GTP_EFTU
UvrD-helicase
Motif
Other DBs
NCBI-GeneID:
125888060
NCBI-ProteinID:
XP_049431196
LinkDB
All DBs
Position
LG4:41418472..41468865
Genome browser
AA seq
2541 aa
AA seq
DB search
MVNQEELEERLKKLLVRLKIPQEDRQLCTLIQIIQDLLFLAHTDTAAELFEGKDVHAPLM
TVLSSHISSKGVQQVGWSLLCRLIEICPNTLEELTRPLKAAKDWEVLGVHQQILKVLSQY
SADCRVTMVGLRALALLLRSDMLPLLVLEEEEDVFSLVVQAMKTFPTSEEVQLQGCGALQ
LLLERVSEDHLVEFVENQDHVVVLAALQRFPDSPELLLQAMKVLLPLAQPVSNVEMLMSG
GARCYSLIIAAMDAFPEVEDLQETACCLFKRFTSESYYNILVLNGVQRVAVRACQTFPDN
AMLQAAALSCLADLTATIVQNKAVAEQGLEEGEEEENRGREEVEDMGLGWMEACCTALEL
HAEEPDVQEAASWAIHNLLLHGAGLNPSEEEQDERTPVHRQLMAAMLLHSSSPSVFQAAT
SAIATLLTHNSKMRSLLLSSGLHVNLVEMMKRHSTSAEVSISACKLLKLLFQGRTASLDE
LNMAMSQILSTMKIHNFQPEVQLEALQASLVFLCPDRSLSEHGVSVADPDMADVSLKVLK
NQCVVEGAHTLYLEVLNRFISSSSIQQCGLKVLSALADCSGAVDLLCQQGAIDTVLHTLQ
MFPQEREIHYWGLTLLNYLVSKKKLSRMIVPVLASVVVASLIQYREDREMLLKCVQVALR
MLDACSGAAAELQREDFDRQIFQHLREETADNPLRKSLCLALSKMRCDPQLNYSMLEKAC
EDGDTILAECLIELGTDINRKTKTESLIYKVCERGGPLDLVELLLSRGVHEQHLRRALAV
SVKRGEGPTVIQLLGRLGLDLNNSALCLGGFRLGRLDAAWLSPLLADRGRTHSLRYNNSK
GMSLAKYIDSLQKSKSTSGPSRSVTDPCLTSGYISDESDDSSFSFVSADDSLFLNDDMES
DGSDSLSGVLSPKARNNSSEELRGGSCKKKQGRRRHASAESGQTENEHSEHVHRRYGRTG
SSQKVFGSGESSAALPKERERIRLLDLSGNELDSLSCLMDDGIVQQQLGHLLRLDLSHNN
LLEFPSALCQSLKSLTRLDLQGNQLQSLPVELLSLLSLSMLNVSRNCVGPVLTFDPAVTC
PSLRQLNLSFNKITTFPQELGRAMDQLEELFLEGNSITELCVPLCLPEIKLLDVSKNSVE
NISPDFLTGCPKLETFSASMNQISSLSHLPSKITTLKLANNSFTCVPEAILHLPNLRSVD
MRTNSITDLPGPGLWESSNLRELMFSQNCIKVLDLSGPIYKWTRLEKLHLSDNKLTEIPP
QIGLLEGLTSLDVSRNANLRSFPDEMGKLGRLWDLPLDGLRLQLDLKLIGSKTKDIVRFL
QQRLKKAVPYYRMKLIVVGNAGSGKTTLIQQLMKLKRSQVNSKQNAVGIDVRDWTIRERD
KKKMVLNVWDFSGGEEFSGSHPHFLTSRALYLVVYNLSKGASQVDALKPWLFNIKAVAPL
SPVILVGTHTDVSDELQLQACLTKTREELLNHQGFPAIRDYHMVSVCEDSDAMTKLRKAI
AREVTSFKIQGQPVMGQLIPDSYVELERRVLQERTRVPPEFPVLRHQELLQLIQESQLQL
DEAELPHAVHFLSEAGVLLHFDDPALQLQDLYFIDPQWLCNIISQKLTSKSCGFWEHPKG
LVQRSVVEKFLSETKCFPKSHLTQFFKLLEKFLIALPFSEDQLLIPSSLSKHRPVIELPH
CENSELIVRLYEMPYFPMDYWSRQISRLLEVSSYLLCGREKPVRPNRIYWRRGVYLSWSP
EAYCLVEAAPEEENPSSFVRVTVPSSRKGRVLLGQVVDHIDSLLEEWFPGLLNTDMHGSG
EALLKKWAQYSFEDGQEWSKILLEDLFPYFEKDFLLPSKEDPSCTLPISQIAPDLLLSDQ
PAGTILDSEELHVDMSKENRLGDGGFGTVYRSVYKNEEVAVKIFNKHASELYINRLLRQE
LAVLGRLRHPSLVGLLAAGSYPQVLVMELALRGSLDSLFEHENGGLNRKLQHRISLQVAD
GLRYLHSAMIIYRDLKPHNVLLFNLKTDSEIIAKITDYGIAQYCCSMGVRSSEGTPGFRA
PEVARGNVIYNQQADVFSFGLLLYDLLTCGERISDGMKFPSEFDEVAVQGKLPDPVKHYG
VSPWPGFQALMKDCLRESPQSRPTSAQVFDRLNSGEMLCLMRELVVPRVFNAECFTVSSG
CRDGASSSHTAWLGGGSSTHRQGSITAMDLDTSRVTTQKVDTSPVLCLVTVQIPTEACDW
LVAGTQSGSLVVISTQDPSTWHHLQSVTDAVTSLYFHVHPRRTQRKNYLLVGTADGVLTV
YEDSVLKQENGQPVKTLTVGNVNTPVMCLGQSMHSLDSRSVWAGCGTKILSFTAEYDVCK
NIDTRPNLIFQQQRSLAGEACVSRMVVDKYIYLSKSGTTTVEVWDKRSERMVDCIDCAQI
IRHDSGCRGRHGSEAELPTEAAPSWARVKALLVQSAATLWIGTRGGHLLLLEISKHQTLQ
VIGPCCRSIRCMASALIETLNWKNVVLVLGRRIPQDTHHVEEESVLMVWNSTLPMEVKDL
NKHCQKREQIAAKLREQLHLD
NT seq
7626 nt
NT seq
+upstream
nt +downstream
nt
atggtgaaccaggaggagctggaggagaggctgaagaaactgctggtgaggctgaagatc
ccgcaggaggaccgacagctgtgcaccctgatccagatcatccaggacctgctgttcctg
gcgcacaccgacactgcagctgaactgtttgaaggcaaagatgtccacgcccccctcatg
acggtgctgtcgtcccacatcagcagcaaaggagtccagcaggttggttggtcattgttg
tgtcggctgattgaaatatgccccaatacgctggaagagttgaccagacctctgaaggca
gccaaggactgggaggtactgggagtgcaccagcagatcctgaaggttctctctcagtac
agcgcagactgcagagtcaccatggttggactcagagctctggctcttctgctcagatca
gacatgcttcctctgctggtgctggaggaagaggaggatgtgttcagcctggtggtgcag
gcgatgaagacgtttcctaccagtgaagaagttcagctccaaggctgcggagctctgcag
ctcctcctggagagagtgagtgaagaccacctggtggagtttgtggagaaccaggatcat
gttgtggttctggcggctctgcagaggttccctgacagccctgagctgctgctgcaggcc
atgaaggtgctgctccctctggctcagcctgtcagtaacgtggagatgctgatgtcagga
ggcgctcgctgctacagcctgatcatcgccgccatggacgccttccccgaggtggaggat
ctgcaggagacggcgtgctgcctcttcaagaggtttacatcagagagctactacaacatc
ctggtactgaatggcgtccagagggtcgcagtgagagcctgtcagactttccccgacaac
gccatgctgcaagccgccgctctctcctgcctggcagacctcactgccaccatcgtgcag
aacaaagcggtggccgagcagggcctggaggaaggagaggaggaggagaacagggggagg
gaggaggtggaggacatgggcctgggctggatggaggcctgctgtacggccctggagctc
cacgctgaggagccggatgttcaggaagctgcaagctgggccatccataacctgttactg
cacggagctggactcaacccttcagaggaggagcaggatgagaggactcctgttcacaga
cagttaatggcggccatgctgctccactcctcctctcccagtgtgtttcaagctgctacc
agtgccatcgccacactcctcacacacaacagtaaaatgcgttctctgctgctgtccagc
ggcctccacgtcaacctagtggagatgatgaagagacattcgacgtcagctgaggtttcc
atcagcgcctgcaaactgctcaaactgctctttcagggaaggacagccagtctggatgag
ttgaacatggccatgagtcaaatcctcagcaccatgaagattcacaacttccagccagag
gttcagctggaggctctgcaggccagtctggtcttcctctgcccagacaggagtttaagt
gagcacggcgtctcggtcgcagatcctgacatggccgacgtgtcattgaaggtcctgaaa
aatcagtgtgtggtggaaggagctcacacactctacctggaagttctcaacaggttcatc
agcagctcgtccatccagcagtgtggtctgaaggtgctgtccgctctggctgactgctcc
ggtgcggtggacctgctctgccaacagggggcgatagacacggtgctgcatacactacag
atgttccctcaggaacgagagatacactactggggtctgaccctgctcaactacctcgtc
tccaagaagaagctgtcgaggatgatcgtacctgttctggcctccgttgttgtcgcctct
ctcatccagtacagagaggacagagagatgctcctgaagtgtgttcaggtggcgttgagg
atgctggacgcctgttcaggagcagctgctgagctgcagagagaagactttgacaggcag
atcttccaacacctcagagaggagaccgctgacaaccccctgcgtaagtcgctgtgtctg
gctctgtctaagatgcggtgcgacccacagcttaactacagcatgctggaaaaggcctgc
gaggacggagacacgatattggctgagtgtctgatcgagctcggcaccgacatcaacagg
aagaccaaaacagaatctctcatctacaaggtgtgtgagagaggcggtcctctggatctg
gtggagctcctgctcagccgaggcgtccacgagcagcacctccgcagggctctggctgtg
agcgtgaagcgtggcgaaggacccaccgtcattcagctgctgggccgtctgggtctggac
ctcaacaacagcgccctctgcctcgggggcttcaggctgggccgcctggacgccgcctgg
ctcagcccgctgctggctgacagaggccgaacgcacagtctgcgttacaacaacagtaaa
ggaatgagtttggccaagtacattgactctttgcagaagtccaagagtaccagcggtcct
tcaagatctgtgaccgacccctgtctgacctccggctacatctctgacgagagcgacgac
tccagcttcagctttgtctccgcagatgacagcttgtttttaaacgacgacatggagagt
gacggaagtgattcactgtccggagttctgtctccaaaggctcgtaataattcgtcagaa
gagctgagaggagggtcgtgcaaaaagaagcagggccgccgcagacacgccagtgcagag
agcggccaaacggagaacgaacacagtgaacatgtgcacaggagatatggaaggaccggc
tccagccagaaagtgtttggatcaggtgagagctctgctgctctgcctaaagagcgagag
aggatccgcctgttggacctgtcgggtaacgagttggactctctgtcttgtctgatggac
gacggcatcgtccagcagcagctgggtcatctcctccgtctggacctgagccacaacaac
ctgctggagttcccctcagctctctgtcagagtttgaagagtctgacccggctggacctg
caggggaaccagctgcagtcgctgccggtggagctgctgtctctgctctcactgagcatg
ctgaacgtctctcgtaactgtgtgggtcccgtcctgacctttgaccccgctgtcacctgc
ccatcactgcgccagctcaacctgtcctttaacaagatcaccacgttccctcaggagttg
ggccgcgccatggaccagctggaggagctgtttttggaagggaacagtataacggagctg
tgtgtgcctctgtgtctgcctgagatcaaactgctcgatgtgagtaagaacagtgtggag
aatatttctccagacttcctgaccggctgccccaaactggaaaccttcagcgcctccatg
aaccaaatcagttctctgtcacatctgccctccaagatcacaacactgaaactagcgaac
aacagcttcacgtgtgttcctgaagccatcctgcatctcccaaacctgcgttcagtggac
atgagaaccaatagcatcactgatctgcccggtccgggactctgggagtccagcaacctc
agagagctgatgttcagtcagaactgtatcaaagtcctggacctgagtgggcccatctac
aaatggaccagactggagaaactccacctgagtgacaacaagctcactgagatccctcca
cagatcggcctgttggaaggcctgacctctttggatgtgagtcgtaacgccaacctccgg
tccttccctgatgagatggggaaactgggccgactgtgggacctgccgctggacggcctt
cgactccagctggacctcaaactcattggcagcaagaccaaagacatcgtccggttcctg
cagcagcgtctgaagaaggcagtgccgtactacaggatgaagctcatcgtggtggggaac
gcaggcagcgggaagaccaccctgatccagcagctgatgaagctgaagcgttcccaagta
aactcaaagcagaacgctgttggtattgacgtcagggactggaccatcagagaacgggac
aagaagaagatggtgcttaacgtctgggacttctcaggtggagaagagttcagcggctct
caccctcacttcctgacgtccagagctctgtacctggtggtttacaacctgagtaaagga
gccagtcaggtggacgccctcaaaccctggctcttcaacatcaaggctgtagctcctctg
tcccctgttatcttggtgggaactcacacagatgtgagcgacgagctgcagcttcaggcc
tgtctgaccaagaccagagaggagctgctgaaccaccagggcttccccgccatcagagac
taccacatggtctccgtctgcgaggactcagacgccatgaccaagctgcgcaaagccatc
gccagagaggtcaccagctttaagatccagggccagcctgtgatgggccagctgattcca
gacagctacgtggagctggagcgccgcgttctgcaggagagaaccagggttcctccggag
ttccccgtcctcagacaccaggagctgctgcagctcatccaggagagtcagctgcagctg
gatgaggccgagctgccccacgctgttcacttcctcagtgaagccggagttttactgcac
tttgatgatcctgctctgcagctccaggacctctactttatcgacccacagtggctgtgc
aacatcatctcacagaagctgacatcaaagagctgtggcttctgggagcaccctaaagga
ctcgtccagcgctcagtggtggaaaagtttctgtctgagactaaatgtttccccaagagt
cacctgacgcagttcttcaaactgctggagaagtttctgatcgctctgcccttcagcgag
gaccagctgctgatacccagcagtttgtccaaacacaggccagtgatcgagctgccgcac
tgtgagaactcagagctgattgtgcgtctgtacgagatgccatacttccccatggattac
tggtctcgccagatcagccgcctgctggaggtttcttcttacttgctttgtggaagagaa
aaacctgtgcggcccaaccgtatctactggaggagaggcgtgtacctgagctggtctccc
gaggcctactgtctggtggaggctgcccccgaggaggagaacccctccagctttgtcagg
gtgaccgtgccctcctcacgcaaaggccgggtgctgctgggtcaggtggtggatcacatc
gactccctgctggaggaatggtttcctggcctcctcaacaccgacatgcatggcagtgga
gaggctctgctgaagaagtgggctcagtacagctttgaggatggccaggagtggagcaag
attctgcttgaggacctctttccatattttgaaaaggattttttgctgccgagcaaggag
gaccctagctgcacgctgcccatctctcagatcgctcctgacctgctgctgagtgaccag
cctgcaggaaccatactggacagtgaagagctgcatgtcgacatgtcgaaagagaacaga
ctgggggacggaggctttgggaccgtctatcgaagtgtctacaaaaatgaagaagtagcc
gtgaaaatattcaacaagcacgcatcagagctttacatcaacagactgctcagacaggag
ttggcggtgttgggtcgcctccgtcaccccagcttggtgggtctgctggcagccggctca
tatcctcaggtgctggtgatggagctggctctgcggggctcactggactcactgtttgaa
cacgagaacggcggcctgaaccgaaaactgcagcacagaatctctctgcaggtggcagac
ggactcaggtaccttcactccgccatgatcatctatcgggatctgaagcctcataacgtc
ctcctgttcaacctcaagaccgactctgagatcatcgccaagatcaccgactacggcatc
gctcagtactgctgcagcatgggagtgaggagctctgagggcacgccaggtttcagagcc
cctgaggtcgcccgaggtaacgtgatctacaaccagcaggctgacgtgttctcgttcggc
ctgctgctctacgacctgctgacttgtggtgagcgcatctctgacggcatgaagttcccc
agtgagtttgatgaggtcgcagtgcagggaaaactgccagatccagtaaaacattacggt
gtgtcaccctggccgggcttccaggctctgatgaaggactgtttgagggagagccctcag
agtcgacccacgtctgctcaggtgtttgatcggctgaactcaggagagatgctgtgcctg
atgagggagctggtggttcctcgggtattcaacgctgagtgcttcacagtgagctccggc
tgcagggacggagcctcgagcagccacacggcctggctgggtggaggcagcagcacccac
agacagggctccatcacagccatggacctggacaccagcagggtcaccacacagaaagtc
gacaccagtcccgtcttgtgtctcgtgaccgtccagatcccaacagaggcctgtgattgg
ctggtggcaggcacccagtctggctccttagtggtcatcagcactcaggacccgtcgact
tggcaccacctgcagagtgtcacagacgctgtcacctcgctgtacttccatgtccaccct
cgccgcacccaaagaaagaattacctgctggttggaacagctgatggagttctcactgtt
tatgaggactctgtgctcaagcaggagaacgggcagccagttaaaactctcaccgtggga
aacgtcaacacgcccgtcatgtgtctgggtcagtcgatgcattctctggacagcaggtct
gtgtgggccggctgcggaaccaagatcctctccttcactgccgaatacgacgtctgcaag
aacatcgacacgagaccaaacctcatcttccagcagcagcggtcattggcaggtgaggcg
tgtgtgtctcggatggttgtggataaatatatttacctgagtaagtctgggacaacgact
gtggaggtttgggataagaggagcgagaggatggtggactgcatcgactgtgctcagatc
atcagacacgactctggctgcagaggcaggcatggcagcgaggcggagctgcccactgaa
gcggctccttcctgggccagagtgaaggccctgctggtgcagagcgctgcaactctctgg
atcggcaccagagggggccacctgctgctgctggagatctccaaacaccagacgctgcag
gtcatcggcccctgctgccgctccatccgctgcatggcctctgcgctcatagaaacacta
aactggaagaatgtggtgctggttttgggcagaaggatcccacaggacacacatcatgtt
gaggaggagtccgtgttgatggtgtggaacagcactctgccgatggaggtcaaagacctg
aacaaacactgccagaaaagagagcagatcgcagccaaactgagagagcagctccatctt
gactga
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integrated database retrieval system
