Epinephelus fuscoguttatus (brown-marbled grouper): 125895453
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Entry
125895453 CDS
T08419
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like isoform X1
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
efo
Epinephelus fuscoguttatus (brown-marbled grouper)
Pathway
efo00562
Inositol phosphate metabolism
efo01100
Metabolic pathways
efo04012
ErbB signaling pathway
efo04068
FoxO signaling pathway
efo04070
Phosphatidylinositol signaling system
efo04140
Autophagy - animal
efo04150
mTOR signaling pathway
efo04210
Apoptosis
efo04218
Cellular senescence
efo04370
VEGF signaling pathway
efo04510
Focal adhesion
efo04620
Toll-like receptor signaling pathway
efo04625
C-type lectin receptor signaling pathway
efo04810
Regulation of actin cytoskeleton
efo04910
Insulin signaling pathway
efo04914
Progesterone-mediated oocyte maturation
efo05132
Salmonella infection
efo05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
efo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
125895453
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
125895453
04370 VEGF signaling pathway
125895453
04068 FoxO signaling pathway
125895453
04070 Phosphatidylinositol signaling system
125895453
04150 mTOR signaling pathway
125895453
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
125895453
09143 Cell growth and death
04210 Apoptosis
125895453
04218 Cellular senescence
125895453
09144 Cellular community - eukaryotes
04510 Focal adhesion
125895453
09142 Cell motility
04810 Regulation of actin cytoskeleton
125895453
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
125895453
04625 C-type lectin receptor signaling pathway
125895453
09152 Endocrine system
04910 Insulin signaling pathway
125895453
04914 Progesterone-mediated oocyte maturation
125895453
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
125895453
09171 Infectious disease: bacterial
05132 Salmonella infection
125895453
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
efo04131
]
125895453
Enzymes [BR:
efo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
125895453
Membrane trafficking [BR:
efo04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
125895453
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_rbd
PI3K_C2
PI3K_p85B
DUF2321
ABC1
Ribosomal_S15
C2
Motif
Other DBs
NCBI-GeneID:
125895453
NCBI-ProteinID:
XP_049443256
LinkDB
All DBs
Position
LG10:complement(12648653..12676462)
Genome browser
AA seq
1068 aa
AA seq
DB search
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSSVKYPEMNAVEDHANWTISRELGFNYNLSGQSNRSARDHALTESDTEQIRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNFRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRQFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
NT seq
3207 nt
NT seq
+upstream
nt +downstream
nt
atgcctcccaggccgtcctcaggggagctatggggcatccacttgatgcctcccaggatc
ctggtggactgcctgctgcccaatgggatgattcttaccctggagtgtctccgtgaggcc
acactcatcaccatcaaacatgagctgttcaaagaggccaggaaatatcccctccatcac
ctcctacaggaagagacgtcctatatcttcgtcagtgttacacaggaagcagagcgggaa
gagttctatgatgagactcgaaggctgtgtgacctccgactcttccagcccttcctcaag
gtcatcgaaccagttggcaacagggaagaaaagatcctcaacagggagattggttttgct
attggtatgcctgtgtgtgaatttgaccttgtgaaggacccagaggttcaggacttcagg
agaaacatcctgaatgtttgtaaagactctgtggagctgagagatgccaacgggccccac
agtagagcactgtatgtttacccacccaatgtggaatccacacaggaacttccaaaacac
atctataacaaactggacaaaggtcaaattattgttgtgatttgggtgattgtttctcca
aacaacgacaaacaaaagtacacattgaagatcaaccacgactgtgtgcctgaacaggtg
attgctgaggccattcgtaagaagacacgcagcatgctgttgtccccagagcagctaaag
atgtgtgttcaggaatatcagggtaaatacatcctcaaagtttgtggctgtgatgagtac
ctgctggaaaagtaccccatcagccaatataagtatatccgtagttgcatcatgctgggc
aggatgcctaacctgatgctaatggccaaggacagcctatacactcagttgcctacagat
aactttgtcatgccatcatactctcgacgcatctccacggcaacatcctatatgaatggt
gaagcagctgccaagtcgctgtggaccatcaatggaacgctgcgaatccggatcctatgt
gccacctatgttaacgtcaatatacgggacatagacaagatatatgtgaggacaggtatt
taccatggaggtgaacagatgtgtgacaatgtcaacactcagagagtaccctgctctaac
cccaggtggaatgagtggctcacgtatgatatgtacatcccagacataccccgtgctgcc
agactctgcctgtccatctgctctgtcaagggcaggaagggagccaaggaggagcactgt
ccactggcgtggggtaatatcaacttgtttgactatactcacactctggtggccaacaaa
atggctctgaacctctggcctgtccctcatggccttgaagacctcctcaaccccatagga
gtcactggatccaaccctaataaggaaaccccatgtctggagctggagtttgaccacttc
agtagttcagtcaaatacccagaaatgaatgcagtcgaggatcatgcaaactggaccatc
tcaagggaactgggctttaactacaacctctctggacagagtaaccggtcggccagagat
cacgccctgacagagagcgacactgagcagataagacagctgagtaacagagaccctctt
tcagaaatcactgagcaggagaaagacttcctctggagacacaggcactactgcatgaat
atccctgagatccttcctaagatccttctcgctgtcaaatggaacttcagagatgaagta
gcacagatgtactgtctgttaaaggaatggccatctattcgtcctgagcaggccatggag
ctgctggactgtaactatcccgaccccatggtcaggcaatttgctgtgcgctgtcttgaa
aaatacctgactgatgacaaactgtctcagtacctcatccagcttgtacaggtattaaaa
tatgagcagtatcttgacaatccgctggcccgtttcctcctcaaaaaggccctgaccaat
caaaggataggtcatttcttcttctggcatctcaagtcagaaatgcacaataaaacagtg
agccagaggtttgggctgctgctagaggcttactgcagggcgtgtggcatgtacctcaaa
cacctcagcaggcaggtagaagccatggagaagctcattaacctcactgacatccttaaa
caggagaaaaaggatgagacacaaaaggtccagatgcggtttcttgtggaccagatgaag
agaccagactacatggatgctctgcagaactacacttctcctctcaaccctgcacaccaa
ctgggaaacttgaggttagatgaatgcaggatcatgtcatcagcaaagaggccattgtgg
ctgaactgggagaatcctgacatcatgtccgagctgctctttcagaacaatgagatcatc
ttcaaaaacggagatgacctgcggcaggatatgctgacgttgcagattattaaaatcatg
gagaatatttggcagaatcagggacttgacctcaggatgcttccgtatggctgtctgtca
ttaggagactgtgtgggtctcatcgaggtggttcgcagctcccacaccatcatgcagatt
cagtgtaaaggaggcttgaaaggagccctgcagttcaactcaaacactctgcatcagtgg
ctcaaggacaagaacaagggcgagatgtatgacatggctgttgatctgtttacgaggtcc
tgtgctggctactgtgtagctacatttattcttgggataggagacagacacaacagcaac
attatggtcaaagatgatggacagttgtttcatatagatttcggccatttcctggatcat
aagaagaagaaatttggctacaagagagagcgagttccttttgtactgacacaagacttc
ctcattgtcatcagcaagggatcccaggagtgcgcaaagaccaaagagtttgagaggttc
caggagatgtgttataaagcctacctggccatccgacagcatgctaacctcttcattaac
ctgttctcgatgatgctgggctctggcatgcctgagctgcagtcatttgatgacattgcc
tacattaggaagacgctggccctggagaaaactgaacaggaggctttggactactttatg
aaacagatgaatgatgctcaccatggaggatggaccaccaagatggactggatattccac
acaattagacagcatgcgctaaactga
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