Eptesicus fuscus (big brown bat): 103297812
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Entry
103297812 CDS
T09083
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus00010
Glycolysis / Gluconeogenesis
efus00020
Citrate cycle (TCA cycle)
efus00620
Pyruvate metabolism
efus00785
Lipoic acid metabolism
efus01100
Metabolic pathways
efus01200
Carbon metabolism
efus01210
2-Oxocarboxylic acid metabolism
efus04066
HIF-1 signaling pathway
efus04922
Glucagon signaling pathway
efus05230
Central carbon metabolism in cancer
efus05415
Diabetic cardiomyopathy
Module
efus_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
103297812 (PDHA1)
00020 Citrate cycle (TCA cycle)
103297812 (PDHA1)
00620 Pyruvate metabolism
103297812 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
103297812 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
103297812 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
103297812 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
103297812 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
103297812 (PDHA1)
Enzymes [BR:
efus01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
103297812 (PDHA1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
103297812
NCBI-ProteinID:
XP_008152778
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All DBs
Position
1:10739405..10753470
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVSSRKFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGMEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGMRVDGMDVLCVREATKFAAAHCRAGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSNEPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgtgtgctgtcgggcgctgcccagaagccggca
agcagagtgctggtgtcatcccggaaatttgcaaatgatgctacatttgaaattaagaag
tgtgaccttcaccggctggaagagggccctcctgtcaccacagtgctcaccagggaggat
ggcctcagatactacaggatgatgcagactgttcgccgaatggagttaaaggcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgacggtcaggaagcttgt
tgtgtgggcatggaagctggcataaatcccacagaccatctgatcacagcctatcgggct
catggctttacctttactcgtgggctttctgtacgagaaattctcgcagagcttacagga
cgtagaggaggctgtgctaaaggaaaaggaggatcaatgcatatgtatgccaagaatttc
tacgggggcaatggcattgttggagctcaggtgcccctgggagctgggattgctctggcc
tgtaagtataatggaaaagatgaggtctgtttgactttgtatggcgatggcgctgctaac
cagggtcagatatttgaagcttacaatatggcagctttgtggaaattaccttgtattttc
atctgtgaaaataaccgctatgggatgggaacgtctgttgagagagcagcagccagcact
gattactacaagagaggggacttcattcctgggatgagggtagatggaatggatgtccta
tgtgtccgggaggcaacaaagtttgcagctgcccattgtagggctggaaaggggcctata
ctaatggagctgcagacttaccgttaccatggacacagcatgagtgatcctggagtcagt
taccgtacacgagaggaaattcaggaagtaagaagtaagagtgaccctatcatgcttctc
aaggatagaatggtgaacagcaatcttgccagtgttgaagaattaaaggaaattgatgtc
gaagtgaggaaagaaattgaggatgctgcccaatttgctacagctgatcctgaaccacct
ttggaagaactaggctatcacatctactccaacgagccaccttttgaagttcggggtgca
aatcagtggattaagtttaagtccatcagttaa
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