KEGG   Eptesicus fuscus (big brown bat): 103302673
Entry
103302673         CDS       T09083                                 
Name
(RefSeq) cytochrome P450 11B1, mitochondrial isoform X1
  KO
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
Organism
efus  Eptesicus fuscus (big brown bat)
Pathway
efus00140  Steroid hormone biosynthesis
efus01100  Metabolic pathways
efus04927  Cortisol synthesis and secretion
efus04934  Cushing syndrome
Module
efus_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:efus00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    103302673
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    103302673
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    103302673
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:efus00199]
    103302673
Enzymes [BR:efus01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     103302673
Cytochrome P450 [BR:efus00199]
 Cytochrome P450, animal type
  CYP11 family
   103302673
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 103302673
NCBI-ProteinID: XP_008157938
LinkDB
Position
19:complement(870709..875353)
AA seq 501 aa
MAFRARAAMVMTGPQHPLRWARALATSAAAAPRAALPFEAMPRCPGSRWLRVLRVWREGS
EDLHLQMQDTFQELGPIFRYDVGGRHMVCVTLPEDVEKLKQAEGGQPRRMVLEPWLAHRQ
QRGHKHGVFLLNGPAWRLDRLRLNPDVMSPQAVQKFVPMVDRVARDFCSALMAKVQQNAR
GSLTLDIQPSIFYYTLEASNLVLFGERLGLLSQSPSRASLDFIHALQAMLESTMRLMFMP
RSLSRWTSPQVWKEHFEAWDCIFQYANSSIKKIYQELALGRPRHYSGVVAELLLHADMTL
DAIKASSIDLTAGSVDTTAYPLLMTLFELARNPEVQQALRQESLQASATISENPQRAAAE
LPLLRAALKETLRLYPVGISVDRLLNSDLVLQNYHIPAGTLITVQLYDQGRNPAVFARPE
LYHPQRWLHRGSGARLPHLAFGFGPRQCLGRRLAEMEMLLLLHHVLKHFQVDTLTQEDIK
MVYRFVLMPSVTPLLTFRALS
NT seq 1506 nt   +upstreamnt  +downstreamnt
atggcattccgggccagggcggccatggtgatgacagggccccagcatcccctgcgctgg
gcgcgggcactggccaccagcgcggctgcggctccccgggcggcgctgcccttcgaggcc
atgccccggtgcccgggcagcaggtggctgcgggtgctgcgcgtctggagggagggctcc
gaggacctgcacctgcagatgcaggacaccttccaggagctggggcccatcttcaggtat
gacgtgggagggaggcacatggtgtgcgtgacgctgcccgaggacgtggagaagctgaag
caggcggagggcggccagccccgcaggatggtcctggagccctggctggcccaccggcag
cagcgcggccacaagcacggcgtgttcttgctaaacgggccggcctggcgcttggaccgc
ctgcggctgaaccccgacgtgatgtcgccgcaggccgtccagaagttcgtccccatggtg
gacagggtggcgagggacttctgcagcgccctgatggcgaaggtgcagcagaacgcacgc
gggagcctgaccctggacatccagcccagcatcttctactacaccctggaagccagtaac
ttggtcctttttggagagcggctgggcctcctcagccagagcccgagccgggccagcctg
gacttcatccacgcgctgcaggccatgctggagtccaccatgcggctcatgttcatgccc
cggagcctgtcccgctggaccagcccgcaggtgtggaaggagcactttgaggcctgggac
tgcatcttccagtacgccaacagctccatcaagaaaatctaccaggagctggcgctcggc
cgcccccggcactacagcggtgtggtggcggagctgctgctgcacgcggacatgacgctg
gacgccatcaaggccagctccatcgacctcacggccggcagcgtggacacgacggcctac
cccctgctgatgaccctcttcgagctggcgcgcaaccccgaggtgcagcaggcgctgcgt
caggagagcctgcaggcctcggccaccatctccgagaacccccagagggccgccgccgag
ctgcccctgctgcgggcggcactcaaggagaccctgaggctgtaccccgtgggcatctct
gtggaccgactgttgaactcggacttggtcctgcagaactaccacatcccggcagggacg
ctgatcacggtgcaactctacgaccaaggacgcaaccccgccgtgttcgcgaggcccgag
ctctaccacccgcagcgctggctgcaccggggctcgggcgccaggctgccccacctggcc
ttcggcttcggcccccgacagtgcctggggcggcgcctggccgagatggagatgctgctg
ctgctgcaccacgtgctgaaacacttccaggtggacacgctcacgcaagaggatatcaag
atggtctaccggttcgtcctgatgccgtccgtcaccccgctgctgaccttccgggccctc
agttag

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