Eptesicus fuscus (big brown bat): 103302997
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Entry
103302997 CDS
T09083
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus00230
Purine metabolism
efus01100
Metabolic pathways
efus04927
Cortisol synthesis and secretion
efus04934
Cushing syndrome
efus05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103302997 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
103302997 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
103302997 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103302997 (PDE8A)
Enzymes [BR:
efus01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
103302997 (PDE8A)
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GFIT
Motif
Pfam:
PDEase_I
PAS_9
PAS
PAS_4
PDE8
PAS_3
PAS_8
Response_reg
Sina_ZnF
Motif
Other DBs
NCBI-GeneID:
103302997
NCBI-ProteinID:
XP_054569175
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All DBs
Position
25:3155098..3276484
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AA seq
832 aa
AA seq
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MGCAPSIHISETQTVYPGARDAEAAPGPAAPLSPPGGPGALLRPEPEALAATSGALPAEP
PQPRDSKVSASQVQFGPMRFHADQLQVLLVFIKEDSQCKGFRKACEKAGFKCTVAQEVQA
VLTCFLAAHHDIIIIDHRNPQQLDAPALCRSIRASKVSENTVIIGVVRRRDGEESVMPLI
SAGFTRRYVENPSLLACYAELLQLEFGEVRSQLKLRACKSVFTALEKSQDAIKITSEDNY
IQYVNPAFETTMGYESGELIGKELAKIPVHEKKADLFTTINSCMKMGKEWQGVYCSKNGD
NVQQNVKIIPVVGQGGKIRHYVSIIRVSNGNSKAEKITESVQSDTPTDSQSGKHKDKRKS
SLDVRSVASRASEVASQRRHSSMARIHSMTIEAPITKVINIINAAQENSSVPVTEALDRV
LEILRSTELYSPQFGAKDEDPHANDLIGGLISDGFRRLSGNEYSLSTKNLQVPSGLFPPA
SLHDVPPRIARAMENEDDWDFNIFELEAATQKRPLIFLGLKIFARFGVCEFLKCSETTLR
LWLQTIEAHYHSANPYHNSTHAADVLHATAYFLCQERVKQTLDSVDEAAALIAAAVHDLD
HPGRTNPFLCNAGSALAVLYNDCAVLESHHAALAFQLTTRDDKSNIFKNMERNDYRTLRQ
AIIDMVLATEMTKHFEHVNKFVNSVIKPLAELEESEESDADPDAIHTMLRAPENRTLIKR
MMIKCADVSNPCRPLEQCIEWAARISEEYFSQTEEEKKLDLPVMMPAFDRNTCSIPKSQI
SFIDYFVTDMYDAWDDFVDLQELLQHLDNNFKYWKGLDERKLRGLRPPLESK
NT seq
2499 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgccccgagcatccacatttccgagacccagaccgtgtacccgggagcccgg
gacgccgaggccgcgccgggccccgcggcgccgctgtccccgccgggcgggccgggcgcc
ctgctccgtccggagcccgaagccttggccgcgaccagcggcgccctccccgcggagccc
ccccagcctcgcgactcgaaggtctcagcatcgcaggtgcagtttggccccatgaggttt
catgcagaccaactccaggtactgttagtgtttatcaaagaagatagccagtgtaaagga
ttccgaaaggcgtgtgaaaaagcggggtttaagtgtacggtggcccaggaggtccaggcc
gtcctgacctgtttcctggctgcacatcacgacatcatcatcatcgaccacaggaacccc
caacagctggatgcaccggcgctgtgcaggtctattcgagcgtcaaaagtttcggaaaac
acagttattattggtgtagtacgcaggcgggatggagaagagtctgtgatgcccctcatt
agtgctggctttacgaggaggtacgtggagaaccccagcctcctggcctgttacgcggag
ctgctccagctggagttcggagaggtgcggtcacagctgaaactcagggcttgtaagtca
gtgttcaccgcactggagaaaagccaggacgccattaagatcacaagtgaggacaactac
atacagtatgtaaatccagcatttgaaacaacaatgggctatgagtcgggtgaattaata
gggaaggagttagcaaaaatacctgtacatgaaaaaaaggctgacttgttcactactata
aactcatgcatgaagatgggcaaggagtggcaaggcgtctactgctccaaaaacggagat
aacgttcaacagaatgtgaagatcatacctgtcgttggacagggagggaaaattagacac
tatgtgtccattatccgagtgagcaacggcaacagtaaggctgagaaaatcacggaatcg
gttcagtctgacacgcccacagatagccaatcaggtaaacacaaagacaagaggaaaagc
tccctggacgtcaggagtgtcgcctcgcgagcaagcgaagtggccagccagagacgacac
tcctccatggcccggatccactccatgaccatcgaggcgcccatcaccaaggtgatcaac
atcatcaacgccgcccaggagaacagttccgtgcctgtgacggaagccttagaccgcgtc
ctggaaatcctgagatccactgagctgtattcaccgcagtttggggcgaaggacgaggat
cctcacgccaacgacctcattgggggcctgatatctgatggttttcgaagactatctggg
aacgagtattctctctcaacaaaaaacctgcaagtcccgagcggcttattcccccccgcg
tcccttcacgacgtcccgccgcggatagctcgggccatggagaacgaggacgactgggac
tttaatatttttgaactggaggctgccactcagaaaaggcctttgatttttcttggtctc
aaaatcttcgctcgcttcggggtctgtgaattcttgaagtgctcggagacgacgctgcgg
ctgtggctgcagactatcgaggcccattaccactccgccaacccctaccacaactccacc
cacgccgccgacgtgctccatgccactgcctacttcctctgccaggaaagggtcaagcaa
acgttagactccgtggacgaggccgccgccctcatcgcagccgccgtccacgacctggac
cacccggggaggaccaacccgttcctgtgcaacgcgggcagcgcgctggccgtgctgtac
aacgactgcgccgtgctggagagccaccacgcggccctggccttccagctgaccaccagg
gacgacaagagcaacatcttcaagaacatggagaggaatgactaccggacgctgcgccag
gccatcatcgacatggtcttggccacggagatgacaaagcactttgagcacgtcaacaag
tttgtcaacagcgtcatcaagcccttggcagagctggaggagagcgaggagagtgatgca
gaccctgacgccatacacacgatgctcagggctccagagaaccggactctcatcaagcgg
atgatgatcaagtgcgctgatgtgtccaacccctgccggcccttggagcagtgcatcgag
tgggctgcacgcatctcggaggagtatttttctcagaccgaggaggaaaagaagctggac
ttacctgtgatgatgccagcttttgaccgcaacacctgcagcatccccaagtcccagatc
tccttcatcgactacttcgtcacagacatgtacgatgcctgggacgactttgtagaccta
caggagttactgcagcatctggacaacaactttaaatactggaagggactcgacgaaagg
aagctgcggggcctccgaccacctctggaatcaaaatag
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