Eumetopias jubatus (Steller sea lion): 114196682
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Entry
114196682 CDS
T07240
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju04140
Autophagy - animal
eju04141
Protein processing in endoplasmic reticulum
eju04210
Apoptosis
eju04932
Non-alcoholic fatty liver disease
eju05010
Alzheimer disease
eju05012
Parkinson disease
eju05014
Amyotrophic lateral sclerosis
eju05016
Huntington disease
eju05017
Spinocerebellar ataxia
eju05022
Pathways of neurodegeneration - multiple diseases
eju05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
114196682 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
114196682 (ERN1)
09143 Cell growth and death
04210 Apoptosis
114196682 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
114196682 (ERN1)
05012 Parkinson disease
114196682 (ERN1)
05014 Amyotrophic lateral sclerosis
114196682 (ERN1)
05016 Huntington disease
114196682 (ERN1)
05017 Spinocerebellar ataxia
114196682 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
114196682 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
114196682 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
114196682 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eju01001
]
114196682 (ERN1)
Enzymes [BR:
eju01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
114196682 (ERN1)
Protein kinases [BR:
eju01001
]
Serine/threonine kinases: Other
IRE family
114196682 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
PQQ_3
Motif
Other DBs
NCBI-GeneID:
114196682
NCBI-ProteinID:
XP_027943205
LinkDB
All DBs
Position
Unknown
AA seq
975 aa
AA seq
DB search
MPARLLLALLALLLLPGPGIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKED
PVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMG
KKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATY
FDYAASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLKK
VMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSM
VHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLRNYW
LLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVS
QDVEEKYEHAPAKPEAPVDSMLKDIATIILSTFLLIGWVAFIITYPLSMQQQQQLQHQQF
QKELEKIQLLQQQLPFHPPGDMAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSTGS
ASKAGTSPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLG
LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRTKAMISDFGLCKKLAVGR
HSFSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFF
QDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLR
AMRNKKHHYRELPAEVQETLGSLPDDFVRYFTSRFPYLLSHTYRAMEPCGHERLFQPYYF
HEPPEPRPPVTPDTL
NT seq
2928 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggctactgctggcgctgctggcgctgctgctgctgcctggccccgggatt
tttggaagtcccagcacagtgacacttcctgaaaccttgttgtttgtgtcaactctggat
ggaagtttgcatgctgttagcaagaggacaggctcgatcaaatggactttaaaagaagat
ccggttctgcaggttccaacacatgtggaagagcctgccttcctcccagatcccaatgat
ggcagcctgtatacgcttgggggcaagaataatgaaggcctgacgaaacttccttttacc
atcccagagttggtacaggcatccccatgccgaagttcagacggaattctctacatgggt
aaaaagcaggacatttggtacgttatcgaccttctgaccggggagaagcagcagactctg
tcatcggcctttgcagacagcctctgcccatctacctctctgctttatctcgggcgaacg
gagtacaccatcaccatgtacgacaccaaaacccgtgagctccggtggaacgccacctac
tttgactatgcagcctctttgcctgaggacgacggggactataagatgtcccactttgtg
tccaacggcgacgggctggtggtgaccgtggacagtgaatccggcgacgtcctgtggatc
caaaactacgcttcccccgtggtggccttttatgtctggcagagggagggtctgaagaag
gtgatgcacatcaacgttgccgtggagaccctgcgctacctgaccttcatgtctggggag
gtgggccgcatcaccaagtggaagtacccgttccccaaggagacagaggccaagagcaag
ctgacgcccaccctgtatgttgggaaatactctaccagcctgtatgcctccccctccatg
gttcacgagggggtcgccgttgtgccccgaggcagcactcttcctttgctggaaggcccc
cagaccgacggggtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagac
ctcaagtttgaccctgggctcaaagggaagaacaagctcaactacctgaggaactactgg
cttctaattggacaccatgaaacccccctgtctgcgtctaccaagatgctggagagattc
cccaacaacctgcccaaacatcgggaaaacgtgattcctgccgattcagagaagaagagc
tttgaggaagttatcaacctggttgaccagacttcagaaaacgcgcctaccaccgtttca
caggatgtggaagagaaatacgagcatgcccctgccaagcccgaggcccccgtggactcc
atgctcaaggacattgccaccatcatcctgagcaccttcctgctcatcggctgggtggcc
ttcatcatcacctaccccttgagcatgcagcagcagcagcagctccagcaccagcagttc
cagaaggaactagagaaaatccagctcctgcaacagcagctgcccttccatccacctgga
gacatggctcaggatgctgagctcttggactcgtccggcctatactccgagagctcgggt
accagcagccccagcacgtcccccagagcctccaaccactcgctgcactccactggctcg
gcctccaaggctggcaccagccccttcctggagcaggacgatgaggatgaggaaaccagc
atggtgatagttgggaagatttcattctgtcccaaggacgtgctgggtcacggagctgag
ggtacgattgtgtaccggggcatgtttgacaaccgtgacgtggctgtcaagaggatcctc
cctgagtgtttcagtttcgcggaccgcgaagtccagctacttcgagaatcggatgagcac
cccaacgtgatccgttacttctgcacagagagggaccggcagttccagtacattgccatc
gagttgtgtgcggccaccctgcaggagtacgtggagcagaaggactttgcccacctcggc
ctggagcccatcaccttgctgcagcagaccacctcaggcctggcccatctccactccctc
aacattgttcatagagacctgaagccccacaacattctcctctccatgcccaacgcgcat
ggcaggaccaaggccatgatctcggacttcggcctctgcaagaagctggcggtaggccgg
cacagtttcagccgccgctcaggagtgccgggcacggaaggctggatcgctccagagatg
ttgagcgaagactgcaaggacaacccgacctacacagtggacatcttctctgcaggctgt
gtcttttactatgtgatctcggaaggcagccacccttttggcaagtccctgcagcggcag
gccaacatcctcctgggtgcctacagcctcgactgcttgcaccccgagaagcacgaagat
gtcattgcccgggaattaatagagaagatgatcgcaatggatcctcagaaacgcccgtcc
gcgaagcacgtgctgaaacatccgttcttctggagcctggaaaagcagctgcagttcttt
caggacgtgagtgaccgaatagaaaaggagtccctggacggcccgatagtgaagcagctg
gagcgaggcgggagagctgtggtgaagatggattggagggagaacatcaccgtccccctg
caaacagatctgcggaaattcagaacctataaaggtggctccgttcgagacctcctccga
gccatgagaaacaagaagcaccactaccgggagctccctgcggaggtgcaggagacgctg
ggttccctccctgacgacttcgtgcgctacttcacgtcccgcttcccctacctcctctcc
catacctaccgggccatggagccgtgcggccacgagcggctcttccagccctactacttc
cacgagcccccagagccccggcctccagtgactccagacaccctttga
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