Eumetopias jubatus (Steller sea lion): 114220134
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Entry
114220134 CDS
T07240
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju00010
Glycolysis / Gluconeogenesis
eju00020
Citrate cycle (TCA cycle)
eju00620
Pyruvate metabolism
eju00785
Lipoic acid metabolism
eju01100
Metabolic pathways
eju01200
Carbon metabolism
eju01210
2-Oxocarboxylic acid metabolism
eju04066
HIF-1 signaling pathway
eju04922
Glucagon signaling pathway
eju05230
Central carbon metabolism in cancer
eju05415
Diabetic cardiomyopathy
Module
eju_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
114220134 (PDHA2)
00020 Citrate cycle (TCA cycle)
114220134 (PDHA2)
00620 Pyruvate metabolism
114220134 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
114220134 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
114220134 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
114220134 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
114220134 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
114220134 (PDHA2)
Enzymes [BR:
eju01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
114220134 (PDHA2)
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Paralog
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
114220134
NCBI-ProteinID:
XP_027973622
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MKKMLAAAVSRVLSWVAQKPASGVLVASCNYSNDATFEIKKCDLYQLEEGPPVTTVLTRE
DGLKYYRMMQTIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCSARGLSVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQGPLGAGVAL
ACKYKGKKEVCLTLYGDGAANQGQIFEAYNMAALWKLPCVFVCENNLYGMGTSAERAAAS
TDYYKRGHFIPGLRVDGMDVLCVREATRFAADYCRSEKGPIVMELQTYRYHGHSMSDPGV
SYRTRQEIQNVRSKSDPIMLLKDRMVNSKLATVEEFKEIDVEVRKEIDDAANFATTDLEP
PLEELGHHIYCNNPPFEVRGASQWIKFKSLS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatgctcgccgctgcggtatcccgcgtgttgtcctgggtcgcccagaagccc
gctagcggagtgctggtggcatcctgtaactattccaatgatgccacatttgaaattaag
aaatgtgacctttatcaattagaagagggtccccctgtcacaacagtgctcacccgggag
gatgggcttaaatactacaggatgatgcagactattcgccgaatggaattgaaggcagat
cagctgtataaacaaaaatttattcgcgggttctgtcacttgtgcgatggtcaggaagct
tgttgtgtgggcctggaggctgggataaatcccaccgatcatgtcatcacatcctatcgg
gctcacggcttatgctctgctcgtggactttctgtccgagcaattcttgcagaactgaca
ggacgaaggggaggctgtgctaaaggaaaaggaggatctatgcatatgtatgcaaagaac
ttctatgggggcaacggcattgtcggtgcccaggggcccctgggagctggtgtcgccctg
gcctgtaaatataagggcaaaaaggaggtctgtttgactctatatggggatggtgctgcg
aatcagggtcagatatttgaagcttacaatatggctgccctgtggaaattaccttgtgtt
ttcgtctgtgagaataacctctatggaatgggcacgtctgctgagagagcagcagcaagc
actgattactacaagagaggacactttatccctggactaagggtggatggaatggatgtt
ctgtgtgttcgggaggcaacgaggtttgccgcggactactgtagatctgaaaaggggccc
atagtgatggagctgcagacataccgttatcatggacacagcatgagtgaccctggagtt
agttaccgcacgcgacaagaaattcagaatgtaagaagtaagagtgatcctattatgctt
ctcaaagatagaatggtaaacagtaagcttgccactgttgaagaattcaaggaaattgat
gtcgaagtgaggaaagaaattgatgatgcagccaactttgctacaactgatcttgaacca
cctttggaagaattaggtcatcacatctattgcaataacccaccttttgaagttcgtggt
gcaagtcagtggatcaagtttaagtccctcagttaa
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