Eumetopias jubatus (Steller sea lion): 114222735
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Entry
114222735 CDS
T07240
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju01524
Platinum drug resistance
eju04010
MAPK signaling pathway
eju04071
Sphingolipid signaling pathway
eju04141
Protein processing in endoplasmic reticulum
eju04210
Apoptosis
eju04530
Tight junction
eju04668
TNF signaling pathway
eju04714
Thermogenesis
eju04722
Neurotrophin signaling pathway
eju04932
Non-alcoholic fatty liver disease
eju04936
Alcoholic liver disease
eju05010
Alzheimer disease
eju05012
Parkinson disease
eju05014
Amyotrophic lateral sclerosis
eju05016
Huntington disease
eju05017
Spinocerebellar ataxia
eju05022
Pathways of neurodegeneration - multiple diseases
eju05208
Chemical carcinogenesis - reactive oxygen species
eju05417
Lipid and atherosclerosis
eju05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
114222735 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
114222735 (MAP3K5)
04668 TNF signaling pathway
114222735 (MAP3K5)
04071 Sphingolipid signaling pathway
114222735 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
114222735 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
114222735 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
114222735 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
114222735 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
114222735 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
114222735 (MAP3K5)
05012 Parkinson disease
114222735 (MAP3K5)
05014 Amyotrophic lateral sclerosis
114222735 (MAP3K5)
05016 Huntington disease
114222735 (MAP3K5)
05017 Spinocerebellar ataxia
114222735 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
114222735 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
114222735 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
114222735 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
114222735 (MAP3K5)
04932 Non-alcoholic fatty liver disease
114222735 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
114222735 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eju01001
]
114222735 (MAP3K5)
Enzymes [BR:
eju01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
114222735 (MAP3K5)
Protein kinases [BR:
eju01001
]
Serine/threonine kinases: STE group
STE11 family
114222735 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
114222735
NCBI-ProteinID:
XP_027977190
LinkDB
All DBs
Position
Unknown
AA seq
1363 aa
AA seq
DB search
MSAEAGEGITFSVPPFAEGGSCRRGGAAVAAEDEESQLPPPPPGSFWNVETAAAPGTGCP
AATSGSSATRCRGNSSSGGGRRTTVAYVINEASQGQLVVAESEALQSLREACETVGATLE
TLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDNN
SDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGP
ICLPLVDRFIQLLKVAQASSSQYFRESILSDIRKARNLYTGKELAAELARIRQRVDNIEV
LTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDR
AKALDVMIPLVQSEGQVASDMYCLVGRIYKDMFLDSNFLDTESRDHGASWFKKAFESEPS
LQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLA
NDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVE
ATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASS
VRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRGTEEGDCES
DSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIAL
HKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQIL
EGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAP
EIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMS
AEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLP
VPVLVGDTSGSSEYGSVSPDAELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDH
SAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEEPKLKWEHIT
TLTASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFSFQDAVNKVLRNHNIK
PHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEDDHEERPSNQTIR
RPHAVIEDAVATSGVSTLSSTVSHDSQNAHRSLNVQLGRMKIETNRLLEELVRKEKELQA
LLHQAIEEKDQEIKHLKLKSQPIGLPLCPRGSPGTNTEDSELTEWLREKGADEDTISRFL
AEDYSLEDVLYYVTRDDLKCLRLRGGMLCTLWKAITDFRDTQT
NT seq
4092 nt
NT seq
+upstream
nt +downstream
nt
atgagcgccgaagcgggcgagggcatcactttctcggtgccacccttcgccgagggcggc
agctgccggaggggaggagcggcggtggcggccgaggacgaggagagccagctaccgccg
ccgccgccgggcagcttctggaacgtagagactgctgcagcccctggcaccggttgtccc
gctgccacctctgggagcagcgccacccggtgccggggcaactctagtagcggaggcggc
cgacggaccacggtggcatatgtgatcaacgaagcgagccaggggcagctggtggtggcc
gagagcgaggccctgcagagcctgcgggaggcgtgcgagacggtgggcgccacactggag
accctgcattttggtaaactggactttggggaaaccaccgtgctggaccgtttttacaat
gcagatattgctgtggtggagatgagtgatgccttccgacagccgtccttgttttaccac
cttggagtgagagaaagtttcagcatggccaacaacatcatcctctactgtgataataat
tcagactctctgcagtcactgaaggaaatcatttgccagaagaatactatgtgcactggg
aactacacatttgtcccttacatgatcactccacataacaaggtctactgctgtgatagt
agcttcatgaaggggttgacagagctcatgcaaccgaactttgagctgcttcttggaccc
atttgcttacctcttgtggatcgtttcattcaacttctgaaggtggcacaagcaagttct
agccagtatttccgggaatctatactcagtgatatcaggaaagctcgaaatttatacact
ggtaaagaattggcagctgaattagcaagaattcggcaacgagtagataatattgaagtc
ttgacagcagatattgtcataaacctcttactttcctacagagatatccaggactatgat
tctattgtgaagctggtagagacattagaaaaacttccaacctttgatttggcttcccat
caccatgtgaagtttcattatgcatttgcactgaataggagaaatctccctggagataga
gcaaaagctcttgatgttatgatcccgctggtgcaaagtgaagggcaggttgcttcagat
atgtattgcctagttggtcgaatctacaaagacatgtttttggactctaatttcctggac
actgagagtagagaccatggagcttcttggttcaaaaaggcatttgaatctgagccatca
ctacagtcaggaattaattacgcggtccttctcctggcggctgggcatcagtttgaatct
tcctttgagctccggaaagttggagtgaagctgagtagcctccttggtaaaaagggaaac
ttagaaaagctccagagctactgggaagttggattttttctgggtgccagtgttctggcc
aatgaccacatgagagtcatccaagcatctgaaaagctttttaaactgaagacaccggca
tggtacctcaagtcgattgtagagacaattttgatatataagcattttgtgaaactgact
accgagcagcctgtggccaaacaagagctcgtggacttctggatggatttcctggtcgag
gccacaaagaccgatgttaccgtagttaggtttccagtattaatattagaaccaaccaaa
atctatcaaccttcatatttgtctatcaacaatgaagttgaggaaaagacgatatctatt
tggcatgtgcttcctgatgacaagaaaggtatacatgagtggaattttagtgcttcttct
gtcaggggagtgagtatttccaaatttgaagaacgatgctgttttctttatgtgcttcat
aattccgacgatttccaaatctatttctgtacagaactgcactgtaaaaagttttttgaa
atggtgaacaccatcactgaagagaaggggagaggcacggaggaaggagattgtgaaagt
gactccctagagtatgactacgaatatgatgagaatggtgacagagtcgttttagggaaa
ggcacttacgggatcgtctacgcaggccgagacctgagcaaccaggtcagaatcgctata
aaggaaatcccagagagagatagcagatactcccagcccctacatgaagaaatagcattg
cataaacatctgaagcacaaaaatattgtccagtatctgggctcttttagtgagaatggt
ttcatcaaaatcttcatggagcaggtcccaggaggaagtctttctgctctccttcgttcc
aaatggggcccattgaaagacaatgagcaaacaattggcttttatacaaagcagatactt
gaaggattaaaatacctccatgacaatcagatagtccaccgggatataaagggcgacaat
gtgttgattaatacctatagtggagttctcaagatctcagacttcgggacatcaaagagg
ctcgctggcataaacccatgtactgaaacttttactggtacccttcagtatatggcacca
gaaatcatagacaaaggtccacgaggctacgggaaagcagcagacatctggtctttgggc
tgcaccatcatcgaaatggccacagggaaaccacctttttatgaactgggagaaccacaa
gcagctatgttcaaggtgggaatgtttaaagtccacccggagatcccagagtccatgtca
gcagaggccaaggcgttcatactgaagtgttttgaaccagaccctgacaagagagcctgt
gctaatgacttgcttgttgatgagttcttaaaagtttcaagcaaaaagaaaaagacacaa
cctaagctttcagccctttcagccggatcaaatgagtatcttcgaagcatatccttgcct
gtgccagtcctggtcggggacacaagcggcagcagtgagtacggctctgtttctcccgat
gcagagttaaaggtggaccccttctctttcaaaacgagagccaagtcctgcggagaaaga
gacgtaaaaggaatacggacactctttttgggcattccagatgaaaattttgaagaccac
agcgctccgccttcccctgaagaaaaagattctggattctttatgctgaggaaggacagt
gagagacgggccacccttcataggatcctgacggaagaccaagacaaagttgtgagaaac
ttaatggaatctttggctcagggggctgaagaacctaaactaaaatgggaacatatcaca
accctcaccgcaagcctcagagaatttgtgagatccacggaccgaaaaatcatcgccacc
acactgtccaagctgaagctagaacttgacttcgacagccacggcattagccaagtccag
gtggtgctcttcagttttcaggatgctgtcaataaagttcttcggaatcataatatcaaa
ccacactggatgtttgccttagacagtatcatccgaaaggcggtgcagacagccattacc
attctggttccagaactgaggccacatttcagcctcgcatctgagagtgataccgctgat
caagaagacttggatgcagaagatgaccatgaggaacggccttcgaaccaaactatccga
agacctcatgctgtcattgaagatgctgtggctacctcaggggtgagcacgctcagttct
actgtatcccacgactctcaaaatgctcaccggtccctcaatgtgcaacttggaaggatg
aaaatagaaactaatagattactggaagaattagttcggaaagagaaagaattacaagca
ctccttcatcaagctattgaagaaaaagaccaagaaattaaacacctgaagcttaagtcc
caaccaataggattgcccctatgcccccggggttctcctggcacaaatactgaagattct
gaacttactgaatggctgagagaaaagggagctgatgaagacactataagtcggtttttg
gctgaggattattcactagaggatgttctctactatgttacacgtgatgatttaaaatgc
ctcagactaaggggagggatgctttgcacactgtggaaggccatcaccgacttccgagac
acacagacttga
DBGET
integrated database retrieval system
