Escherichia coli KO11FL: KO11_00565
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Entry
KO11_00565 CDS
T02104
Symbol
acnB
Name
(GenBank) bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
KO
K01682
aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:
4.2.1.3
4.2.1.99
]
Organism
ekf
Escherichia coli KO11FL
Pathway
ekf00020
Citrate cycle (TCA cycle)
ekf00630
Glyoxylate and dicarboxylate metabolism
ekf00640
Propanoate metabolism
ekf01100
Metabolic pathways
ekf01110
Biosynthesis of secondary metabolites
ekf01120
Microbial metabolism in diverse environments
ekf01200
Carbon metabolism
ekf01210
2-Oxocarboxylic acid metabolism
ekf01230
Biosynthesis of amino acids
Module
ekf_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ekf_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
ekf_M00012
Glyoxylate cycle
Brite
KEGG Orthology (KO) [BR:
ekf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
KO11_00565 (acnB)
00630 Glyoxylate and dicarboxylate metabolism
KO11_00565 (acnB)
00640 Propanoate metabolism
KO11_00565 (acnB)
Enzymes [BR:
ekf01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.3 aconitate hydratase
KO11_00565 (acnB)
4.2.1.99 2-methylisocitrate dehydratase
KO11_00565 (acnB)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase_2_N
Aconitase_B_N
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AFH15102
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Position
133078..135675
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AA seq
865 aa
AA seq
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MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEFLLDLLTNRVPPGVDEA
AYVKAGFLAAIAKGEAKSPLLTPEKAIELLGTMQGGYNIHPLIDALDDAKLAPIAAKALS
HTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRPVLAEKLTVTVFKVTGETNTD
DLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVGPIKQIEALQQKGFPLAYVGDVV
GTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSN
LNMGDVIDVYPYKGEVRNHETGELLATFELKTDVLIDEVRAGGRIPLIIGRGLTTKAREA
LGLPHSDVFRQAKDVAESDRGFSLAQKMVGRACGVKGIRPGAYCEPKMTSVGSQDTTGPM
TRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVNTHHTLPDFIMNRGGVSLRPGDGVIH
SWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKM
QPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQAFELTDASA
ERSAAGCTIKLNKEPIIEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEA
DADAEYAAVIDIDLADIKEPILCAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAA
GKLLDAHKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVA
DGATVVSTSTRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDT
YRYLNFNQLSQYTEKADGVIFQTAV
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
gtgctagaagaataccgtaagcacgtagctgagcgtgccgctgaggggattgcgcccaaa
cccctggatgcaaaccaaatggccgcacttgtagagctgctgaaaaacccgcccgcgggc
gaagaagaattcctgttagatctgttaaccaaccgtgttccccctggcgtcgatgaagcc
gcctatgtcaaagcaggcttcctggctgctatcgcgaaaggcgaagccaaatcccctctg
ctgactccggaaaaagccatcgaactgctgggcaccatgcagggtggttacaacattcat
ccgctgatcgacgcgctggatgatgccaaactggcaccgatcgctgccaaagcactttct
cacacactgctgatgttcgataacttctatgacgtagaagagaaagcgaaagcaggcaac
gaatatgcgaagcaggtaatgcagtcctgggcggatgccgaatggttcctgaatcgcccg
gtgctggctgaaaaactgaccgttaccgtcttcaaagtcactggcgaaaccaacaccgat
gacctttctccggcaccggatgcgtggtcgcgcccggatatcccactgcacgcgctggcg
atgctgaaaaacgcccgtgaaggtattgagccagaccagccaggtgttgttggcccgatc
aaacagattgaagctctgcaacagaaaggtttcccgctggcgtacgtcggtgacgttgtg
ggtacgggttcatcgcgtaaatccgccacgaactccgttctgtggtttatgggcgatgat
attccacatgtgccgaacaaacgcggcggtggtttgtgcctcggcggtaaaattgcaccc
atcttctttaacacgatggaagacgcgggtgcactgccaatcgaagtcgacgtctctaac
ctgaacatgggcgacgtgattgacgtttacccgtacaaaggtgaagtgcgtaaccacgaa
acaggcgaactgctggcgaccttcgaactgaaaaccgacgtgctgattgatgaagtgcgt
gctggcggccgtatcccgctgattatcgggcgtggcctgaccaccaaagcgcgtgaagca
cttggtctgccgcacagtgatgtgttccgtcaggcgaaagatgtcgctgagagcgatcgc
ggcttctcgctggcgcagaaaatggtaggccgtgcctgtggcgtgaaaggcattcgtccg
ggcgcgtactgcgaaccgaaaatgacttctgtaggctctcaggacaccaccggcccgatg
acccgtgatgaactgaaagacctggcgtgcctgggcttctcggctgacctggtgatgcag
tctttctgccacaccgcggcgtatccgaagccagttgacgtgaacacgcaccacacgctg
ccggacttcattatgaaccgtggcggtgtgtcgctgcgtccgggtgacggcgtcattcac
tcctggctgaaccgtatgctgctgccggataccgtcggtaccggtggtgattcccatacc
cgtttcccgatcggtatctctttcccggcgggttctggtctggtggcatttgcagccgca
acaggcgtaatgccgctggatatgccggaatccgttctggtgcgcttcaaaggcaaaatg
cagccgggcatcaccctgcgcgatctggtacatgccattccgctgtatgcgatcaaacaa
ggtctgctgaccgttgagaagaaaggcaagaaaaacatcttctctggccgcatcctggaa
attgaaggtctgccggatctgaaagttgagcaggcatttgaactgaccgatgcgtccgcc
gagcgttctgccgctggttgtaccatcaagctgaacaaagaaccgatcatcgaatacctg
aactctaacatcgtcctgctgaagtggatgatcgcggaaggttacggcgatcgtcgcacc
ctggaacgtcgtattcagggcatggaaaaatggctggcgaatcctgagctgctggaagcc
gatgcagatgctgaatacgcggcagtgatcgacatcgatctggcggatattaaagagcca
atcctctgtgcaccgaacgacccggatgacgcgcgtccgctgtctgcggtacagggtgag
aagatcgacgaagtatttatcggttcctgcatgaccaacatcggtcacttccgtgctgcg
ggtaaactgctggatgcgcacaaaggccaactgccgacccgcctgtgggtggcaccgcca
acccgtatggacgccgcgcagttgactgaagaaggctactacagcgtcttcggtaagagt
ggtgcgcgtatcgagatcccgggctgttctctgtgtatgggtaaccaggcgcgtgtagca
gacggtgcgacggtggtttccacctctacccgtaacttcccgaaccgtctgggtactggc
gcgaatgtcttcctggcttctgcggaactggcggctgttgcggcgctgattggcaaactg
ccgacgccggaagagtaccagacctacgtggcgcaagtagataaaactgccgttgatact
tatcgttatctgaacttcaaccagctttctcagtacaccgaaaaagccgatggggtgatt
ttccagactgcggtgtaa
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