Enhydra lutris kenyoni (northern sea otter): 111144941
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Entry
111144941 CDS
T05871
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk00562
Inositol phosphate metabolism
elk01100
Metabolic pathways
elk04014
Ras signaling pathway
elk04015
Rap1 signaling pathway
elk04020
Calcium signaling pathway
elk04024
cAMP signaling pathway
elk04070
Phosphatidylinositol signaling system
elk04919
Thyroid hormone signaling pathway
elk04933
AGE-RAGE signaling pathway in diabetic complications
elk05205
Proteoglycans in cancer
Module
elk_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
111144941
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
111144941
04015 Rap1 signaling pathway
111144941
04020 Calcium signaling pathway
111144941
04070 Phosphatidylinositol signaling system
111144941
04024 cAMP signaling pathway
111144941
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
111144941
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
111144941
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
111144941
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
elk04131
]
111144941
Enzymes [BR:
elk01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
111144941
Membrane trafficking [BR:
elk04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
111144941
Endocytosis
Macropinocytosis
Phospholipase C
111144941
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
111144941
NCBI-ProteinID:
XP_022355261
UniProt:
A0A2Y9J428
LinkDB
All DBs
Position
Unknown
AA seq
2294 aa
AA seq
DB search
MTSEEMAASVLTPVTQRKVTSTPSAIDESSEKVSDISVLKAHSIRQSGQTSTTAQMNKLK
EEPSGSNLPKILSTAREKIVSDENSNEKCWTESTPVSVENLNINQNDILTKSQCYDTCDS
VTQEDPYLETGIPSSLERKVFPGIQLEIDGPPMDISPLGSQSAIIETGQAHPDGNTAAFH
FHYEVDRRVSDTFCTLSGNLILDDCGNCVPLPDVGGEQKKNYEAYTCKLMELAENCDNKN
GQLQCDHCDTLDDKYLCFEGSCRRASVLCSSDSLCREDLTNSPPAKTFLSHFEDFPDNCE
DVEEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLPSGHIGLEAYSYIDQKR
SGLLLPCGRFLEQLSVVAIRQDGSQCLSEAQWYRIYNAVRSGEEIENTTESLLHVFTRLP
ASEAAHERISIGPCLKRCVQDTICEYRATLQRTSISQYITGSLLEATTSLGARSGLLSTF
GGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILMEQEQNIY
RRVLPVDYLCFLTRDLGTPECQTSLPCLKASISASILTSQNGEHNALEDLVMRFNEVSSW
VTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQSD
LETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGLMKLC
PRYNSQEETLEFVADYSGQDNFLQRVGHNGLKNSEKESTVNSIFQTIRSCSRSLEAEDED
SPREGNSSRKNSLRDKARWQFIIGDLLDSENDLFEQSKEWDSHGSEEPQKAFDHGTELIP
WYVLSIRADVHQFLLQGATVIHYDQDAHLSARCFLQLQPDNSTLTWIKPTTASPASAKAK
LGVLSNTSEPGKFPLLGNAGLSGLAEGVLDLFSAKAVYMGHPSIDIHTVCVQNKLGSMFL
SETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQQWLRKQY
VSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPSVQRNNTLGISTTKKK
KKILIRGESGEAADDEMATRKAKMQRESRSRSGSDPQDMNEQEESEANAVMSPPNTLPSR
RAHSLTTAGSPNLSAGTSSPIRPVSSPVLSSSNKSLSSAWSSSSWHGRIKGGMKGFQSFM
VSDSNMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCSRAGSESAPLYTNLTIDENTSDL
QPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGIFGVGIL
QLNDFLVNCQGEHCTYDEILSIIQKFEPSVSMCHQGLLSFEGFARFLMDKDNFASKNDES
QEDIKDLQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGM
PIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGE
KLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQAY
NGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKRI
KKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNASG
SSRGKERKSRKSIFGNNPGRMSPGETASFNKASGKSSCEGMRQAWEESSSPLNPTTSLSA
IIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLMFWLH
GIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSME
PAVYSLTIVSGQNVCPNSSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFR
VHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFINSRR
MEENSSSSAVPASLMFNTEERKCLQTHKVTVHGVPGPEPFTVFSINGGTKAKQLLQQILT
TEQDTKPIVTDYFLMEEKYFISKEKNECRKQPFQRVIGPEEEIMQILSSWFPEEGYVGRI
VLKTQQENLEERSIIQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQ
TLCKAKYSYSILSNPNPSDYVLLEEVVKDATKKSSTPKSSQRVLLDQECVFQAQSKWKGA
GKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLTSPSQVLASENVQSKEEKS
VGSLPSSDAIDYGQ
NT seq
6885 nt
NT seq
+upstream
nt +downstream
nt
atgacgtcagaagaaatggcagcttctgttctcacacctgtaactcagagaaaagtaaca
tccactccatcggctatagatgaaagtagtgaaaaggtctcagacatcagtgttctgaag
gcacatagcatcaggcagagtgggcagacttctaccactgcacagatgaacaaacttaaa
gaagaaccttctggaagcaacttacccaagattctctcgacagcaagggagaaaatagtg
agcgatgagaacagcaatgaaaagtgctggacagaaagcacaccagtttctgtggaaaac
cttaacattaaccaaaacgacatactgacaaagagccagtgttatgacacgtgcgattct
gtcacgcaggaagacccatatttggaaactggaatcccgtcctcactggaaagaaaggtg
ttccctggaattcaactggaaattgatggacctcccatggacattagtcccttaggaagt
cagtcggccatcatagagactggccaggcacaccctgatggcaacacagcagcatttcac
tttcactatgaagttgacagaagagtgtcagatactttctgtaccctgtcaggcaacttg
attttagatgattgtggaaactgtgtaccactgcctgatgttggtggggagcaaaagaaa
aattatgaggcatatacttgtaaacttatggaattggctgaaaactgtgataataagaat
gggcagctgcagtgtgatcattgtgacaccttggatgacaaatacttatgctttgaaggt
tcttgccgaagggccagtgtgctatgttcaagtgacagcctttgcagggaggacttgact
aacagtccccctgccaagacttttctgagccattttgaggacttccctgataactgtgaa
gatgtagaagaagatttttttaagagcaaaaaggagaggtccactttgttagtgaggaga
ttttgtaaaaatgacagggaagtaaagaaatctgtgtataccgggacaagagcaatcatg
aggactctgccttctggtcacattgggctggaagcttacagttatatcgatcagaagaga
agtggtcttttattgccctgtgggagatttctggaacagctgtcagtggtggcgattagg
caggatggaagccagtgcctatcagaagcccagtggtatcggatctacaatgcagtgaga
agcggagaagaaatagaaaatacaactgaatctcttctccatgtcttcacaaggctcccg
gcctccgaggcagcccatgaaaggattagcattggtccatgcttaaaacggtgtgtccaa
gacaccatatgtgagtatcgggccacgctccagagaacgtccatatctcagtacatcacg
ggctctctcctagaagcaaccacatctttgggagcaagaagtggcctactcagtactttt
ggaggatccactggacgaatgatgctaaaagaacgccagccaggcacctccatggccaat
tccagtgccctcccttcaagttcagctgggatcagcaaggagctgattgacctccagccc
ctcattcaattcccagaggaagtcgccagcatcctgatggagcaggaacagaacatttac
cgaagggtcttgccagttgactacctttgcttcttgacccgggacttaggcactccggaa
tgccagacatccctgccctgcctcaaagcatccatctcagcttcgattcttacctcccag
aatggagagcacaatgccctggaagatctggtgatgagatttaatgaggtgagctcttgg
gtgacgtggctgatcctcacggcaggctccatggaggagaagcgagaagtcttctcgtat
ttggtgcatgtggccaaatgctgctggaacatgggcaactacaatgctgtcatggagttc
ttggctggcctcaggtcaaggaaagttttaaaaatgtggcagtttatggaccagtctgac
ctggagaccatgaggagcctgaaagacgccatggctcagcacgaatcttcctgcgagtac
aggaaggtggtcacgcgggccctgcacatacccggctgtaaggtggttccgttctgtggg
gtgtttctgaaggagctctgtgaagtactggacggagcctctggcctcatgaagctttgc
ccgaggtacaattcccaagaagaaactctagagtttgtagccgattacagcggacaagat
aatttcttacaacgagtgggacataatggtttaaagaattcagagaaggagtccactgtc
aacagcatctttcagaccatcagaagctgcagccgaagtctggaggcagaggatgaagac
agcccccgcgaaggcaatagctctagaaaaaattccttgagggataaagcacggtggcag
tttataattggagatctgttggattctgaaaatgacctctttgagcagtcgaaagaatgg
gactctcatggatcagaagagccacagaaggcctttgaccatggcacggagctgatcccg
tggtatgtgctgtccatccgagctgatgtgcaccagttcctactgcagggggccactgtc
atccactatgaccaggatgcgcacctgtccgcccgctgcttcctgcagcttcagcctgac
aacagcaccttgacctggataaagcccaccactgcctccccagccagtgctaaagcaaaa
cttggtgtgcttagtaacacatctgagcctggcaaattccccttactgggcaatgctgga
ttaagtggcctggcggagggggtcttggatctgttttcagcaaaggctgtgtacatggga
caccctagcattgatatacacactgtgtgtgttcagaacaaactgggtagcatgtttctc
tccgagactggcgtgacactgctctatgggctccagaccacagacaatagattattgcac
tttgtggcgcccaagcacacagctaagatgctcttcagtggactgctagaactcacaagg
gccgtgaggaagatgaggaagttccctgaccagagacagcagtggctgcggaaacagtac
gtcagcctctatcaggaggatggacggtatgaaggcccaactttggctcacgctgtggag
ctgttcggtggccggcgatggagtacacgcaaccccagccccgggacatctgcgaagagt
gctgagaagcccagtgtgcagaggaacaacacgttgggcataagcaccaccaagaaaaag
aagaaaatccttatacggggtgagagtggagaggcggccgacgacgagatggccacgcgg
aaggccaaaatgcagagggagagtcgcagccggagtggttcagaccctcaagacatgaat
gagcaagaagaatccgaggcaaatgccgtcatgagccctcctaacactctgccttccaga
agagcccactctttgaccacggctgggtcccccaacttgtctgctgggacatcatctccc
atcaggccagtgtcttcccctgtgctgtcttcttcaaacaagagcctgtccagtgcttgg
agcagcagcagctggcacgggaggatcaaaggaggaatgaagggttttcagagcttcatg
gtttccgacagtaacatgagtttcgttgaatttgttgagctgttcaaatcattcagcgtg
aggagccgcaaggacctaaaggatctctttgacatctacgccgtgccctgcagccgagcc
ggctctgagtcagcccctctctacaccaacctaaccatcgacgaaaacaccagtgatctt
cagcctgacctagatttactgaccagaaatgtctcagacttggggttgttcattaagagt
aaacagcagctgtcagacaaccagaggcagatatctgatgccattgctgctgcgagtatc
gtgacaaatggcactggggtcgagagcacgtctctgggcatctttggggtcggcatactc
cagctcaatgacttccttgtcaactgccagggagagcactgcacttacgatgaaatcctc
agtatcattcagaagttcgagcctagcgttagtatgtgtcatcagggcctactgtcattt
gagggatttgcaaggtttctgatggataaagacaattttgcctccaaaaatgacgagtca
caggaagacattaaagacttgcagctgcccctgtcctactattacattgaatcttcacac
aatacctacctcacaggccaccagctcaaaggagagtcctcagtggaactctacagtcag
gtcctcctacaaggctgcaggagtgtagagttggactgctgggatggagatgatgggatg
cccatcatctaccatgggcacacgctgacaaccaagatccccttcaaggaggtggttgaa
gccattgaccgcagtgccttcatcaactctgacctgccaatcatcatatcaattgagaac
cactgctcattgcctcagcaacgaaaaatggcagaaattttcaagactgtgtttggagaa
aaactggtggctaaattcctgtttgagagcgatttctcagatgatccaatgcttccctca
cctgaccaacttaggaggaaagtgcttcttaaaaataagaagctaaaagctcaccagaca
ccagtggatatcttaaagcaaaaggctcatcagttagcatccatgcaagctcaggcctat
aatgggggaaatgccaaccccccacctgctaataacgaggaagaggaggatgaagaggat
gaatatgattatgactatgaatctctgtctgatgacaacattctagaagacagacctgaa
aataaatcatgtaatgacaagcttcagtttgagtataatgaagaaatccccaagaggata
aagaaagcagataactctgcctgcaacaaaggaaaggtttatgacatggaattgggggaa
gaattttatcttcctcagaataaaaaggaaagcagacagattgcaccggagctttctgac
cttgtcatctattgccaagctgtaaaatttccaggcctgtcaactctaaatgcatctggc
tctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggcaga
atgagccctggggagacagcatcgtttaacaaagcatctggaaaaagttcctgtgaagga
atgcggcaggcctgggaggaatcttcttcccccctgaacccaaccacatccctcagcgct
atcattagaactcccaaatgttaccatatatcatcgctgaatgaaaatgccgccaaacgt
ctgtgtcgcaggtattctcagaaactgatccagcacaccgcctgtcagctgctgaggact
tacccggctgccacccgcatcgactcctccaaccccaatcccctcatgttctggctccat
gggatacagctcgtggcgctcaactaccagacagatgatctccccttacatttaaatgct
gccatgtttgaggccaacggtggctgtggctatgttctgaaacccccagttctgtgggac
aagaactgtcccatgtatcaaaagttttcacccttggaaagagacctggacagcatggag
cctgccgtctattccttaactatcgtctctggtcaaaacgtgtgtccaaacagcagcacg
gggagcccgtgcatcgaagtcgacgtcctgggtatgcccctggacagctgccacttccgc
acaaagcccatccaccggaacactctgaaccccatgtggaacgaacagtttctcttccgg
gttcactttgaagacctcatatttcttcgttttgcggttgtggagaacaacagctcggct
gtaaccgctcagagaatcatcccactcaaggctttaaaacgaggttatcggcatcttcag
ctgcgaaacctccacaatgaagtcttggaaatctctagtttattcataaacagcagaagg
atggaagaaaattcctccagcagtgctgtgccggcctctttgatgtttaatacagaagaa
agaaaatgtttgcagactcacaaagtcacagtgcatggggtcccgggtccagagcccttt
actgttttctccataaatggtggcaccaaggcaaagcaacttctccaacaaattctgacg
actgaacaagacaccaaacctattgtcacagactattttttgatggaagaaaaatatttt
atatctaaagaaaagaatgaatgcaggaaacaaccattccagagagtcattggtccagaa
gaagagatcatgcagattttaagcagctggtttccagaggaaggctatgttggcaggatt
gtcttaaaaacccagcaggaaaacctagaagagagaagcattattcaagatgacaaggag
gtgatcttgagctcagaggaggagagtttctttgtccaagtgcatgacgtttctccagag
caacctcgaacggtcatcaaagcgccccgtgtcagcaccgcacaggatgtcattcagcag
accttatgcaaagccaaatattcctatagcatcctgagcaaccccaacccgagtgactat
gtgcttttggaagaggtggtgaaagatgctaccaagaagtcttctaccccgaagtcctcc
cagagggttcttttggatcaggaatgtgtgtttcaagcccagagcaagtggaaaggtgca
ggaaaattcatacttaagctaaaggagcaggtgcaggcatccagagaagacaaaagaaaa
ggcatttcttttgcaagtgaattcaagaagttcaccaagtcaactaaacagccccgagga
ctcacatcaccttctcaggtcttggcctcagaaaatgtccaaagcaaggaggagaaatca
gtgggcagcttgccctccagtgacgccatagactacggacaataa
DBGET
integrated database retrieval system
