Enhydra lutris kenyoni (northern sea otter): 111157628
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Entry
111157628 CDS
T05871
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk01522
Endocrine resistance
elk04010
MAPK signaling pathway
elk04015
Rap1 signaling pathway
elk04068
FoxO signaling pathway
elk04071
Sphingolipid signaling pathway
elk04114
Oocyte meiosis
elk04148
Efferocytosis
elk04218
Cellular senescence
elk04261
Adrenergic signaling in cardiomyocytes
elk04370
VEGF signaling pathway
elk04380
Osteoclast differentiation
elk04550
Signaling pathways regulating pluripotency of stem cells
elk04611
Platelet activation
elk04613
Neutrophil extracellular trap formation
elk04620
Toll-like receptor signaling pathway
elk04621
NOD-like receptor signaling pathway
elk04622
RIG-I-like receptor signaling pathway
elk04625
C-type lectin receptor signaling pathway
elk04657
IL-17 signaling pathway
elk04658
Th1 and Th2 cell differentiation
elk04659
Th17 cell differentiation
elk04660
T cell receptor signaling pathway
elk04664
Fc epsilon RI signaling pathway
elk04668
TNF signaling pathway
elk04670
Leukocyte transendothelial migration
elk04714
Thermogenesis
elk04722
Neurotrophin signaling pathway
elk04723
Retrograde endocannabinoid signaling
elk04728
Dopaminergic synapse
elk04750
Inflammatory mediator regulation of TRP channels
elk04912
GnRH signaling pathway
elk04914
Progesterone-mediated oocyte maturation
elk04917
Prolactin signaling pathway
elk04926
Relaxin signaling pathway
elk04932
Non-alcoholic fatty liver disease
elk04933
AGE-RAGE signaling pathway in diabetic complications
elk04935
Growth hormone synthesis, secretion and action
elk04936
Alcoholic liver disease
elk05014
Amyotrophic lateral sclerosis
elk05020
Prion disease
elk05022
Pathways of neurodegeneration - multiple diseases
elk05132
Salmonella infection
elk05133
Pertussis
elk05135
Yersinia infection
elk05140
Leishmaniasis
elk05142
Chagas disease
elk05145
Toxoplasmosis
elk05152
Tuberculosis
elk05161
Hepatitis B
elk05163
Human cytomegalovirus infection
elk05167
Kaposi sarcoma-associated herpesvirus infection
elk05169
Epstein-Barr virus infection
elk05170
Human immunodeficiency virus 1 infection
elk05171
Coronavirus disease - COVID-19
elk05205
Proteoglycans in cancer
elk05208
Chemical carcinogenesis - reactive oxygen species
elk05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
elk05415
Diabetic cardiomyopathy
elk05417
Lipid and atherosclerosis
elk05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111157628
04015 Rap1 signaling pathway
111157628
04370 VEGF signaling pathway
111157628
04668 TNF signaling pathway
111157628
04068 FoxO signaling pathway
111157628
04071 Sphingolipid signaling pathway
111157628
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
111157628
09143 Cell growth and death
04114 Oocyte meiosis
111157628
04218 Cellular senescence
111157628
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
111157628
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
111157628
04613 Neutrophil extracellular trap formation
111157628
04620 Toll-like receptor signaling pathway
111157628
04621 NOD-like receptor signaling pathway
111157628
04622 RIG-I-like receptor signaling pathway
111157628
04625 C-type lectin receptor signaling pathway
111157628
04660 T cell receptor signaling pathway
111157628
04658 Th1 and Th2 cell differentiation
111157628
04659 Th17 cell differentiation
111157628
04657 IL-17 signaling pathway
111157628
04664 Fc epsilon RI signaling pathway
111157628
04670 Leukocyte transendothelial migration
111157628
09152 Endocrine system
04912 GnRH signaling pathway
111157628
04914 Progesterone-mediated oocyte maturation
111157628
04917 Prolactin signaling pathway
111157628
04926 Relaxin signaling pathway
111157628
04935 Growth hormone synthesis, secretion and action
111157628
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
111157628
09156 Nervous system
04728 Dopaminergic synapse
111157628
04723 Retrograde endocannabinoid signaling
111157628
04722 Neurotrophin signaling pathway
111157628
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
111157628
09158 Development and regeneration
04380 Osteoclast differentiation
111157628
09159 Environmental adaptation
04714 Thermogenesis
111157628
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
111157628
05208 Chemical carcinogenesis - reactive oxygen species
111157628
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
111157628
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
111157628
05161 Hepatitis B
111157628
05171 Coronavirus disease - COVID-19
111157628
05163 Human cytomegalovirus infection
111157628
05167 Kaposi sarcoma-associated herpesvirus infection
111157628
05169 Epstein-Barr virus infection
111157628
09171 Infectious disease: bacterial
05132 Salmonella infection
111157628
05135 Yersinia infection
111157628
05133 Pertussis
111157628
05152 Tuberculosis
111157628
09174 Infectious disease: parasitic
05145 Toxoplasmosis
111157628
05140 Leishmaniasis
111157628
05142 Chagas disease
111157628
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
111157628
05020 Prion disease
111157628
05022 Pathways of neurodegeneration - multiple diseases
111157628
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
111157628
05418 Fluid shear stress and atherosclerosis
111157628
05415 Diabetic cardiomyopathy
111157628
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
111157628
04932 Non-alcoholic fatty liver disease
111157628
04933 AGE-RAGE signaling pathway in diabetic complications
111157628
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
111157628
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
elk01001
]
111157628
Enzymes [BR:
elk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
111157628
Protein kinases [BR:
elk01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
111157628
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Motif
Other DBs
NCBI-GeneID:
111157628
NCBI-ProteinID:
XP_022374918
UniProt:
A0A2Y9KUH7
LinkDB
All DBs
Position
Unknown
AA seq
486 aa
AA seq
DB search
MSSPPPARRGFYRQEVTRTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELYAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRIQFLVYQMLKGLKYIHAAGIIHRVGPRGGGRSPWPIGEGGAWLPGAPIAGA
QLLGARDQCPSWKGCWVGLTGGGERGLFSAYAPMGGAARPPLSCPQDLKPSNLAVNEDCE
LKILDFGLARQADSEMTGYVVTRWYRAPEVILNWTRYTQTGEKLPRDAEPPWRQPPGPHP
PASNSSWEVRGRLLPGKAAELGWEPVDIWSAGCIMAEMITGKTLFKGSDHLDQLKEIMKV
TGTPPAEFVQRLQSADAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAERRVT
AAEALTHPYFESLQDTEDEPTAQKYDESFDDMDHTLDEWKRVTYKEVLSFKPPRQLGTKV
SKETAL
NT seq
1461 nt
NT seq
+upstream
nt +downstream
nt
atgagctcgccgccgcccgcccgtaggggcttctaccgccaggaggtgaccaggacggcc
tgggaggtgcgcgccgtgtaccaggacctgcagcccgtgggctcgggcgcctacggcgcg
gtgtgctcggcggtggacagccgcactggcgccaaggtggccatcaagaagctgtaccgg
cccttccagtccgagctgtacgccaagcgcgcctaccgcgagctgcgtctcctcaagcac
atgcgccacgagaacgtcatcgggctgctggatgtgttcactcctgatgaaaccctggat
gatttcacagacttttacctggtgatgccgttcatggggactgacctgggcaagctcatg
aagcacgagaagctgagtgaggaccgaatccagttcctcgtctaccagatgctgaagggg
ctaaagtatatccatgctgctggcatcatccacagggtaggtcctcgtggtggtgggagg
tccccctggcctataggtgagggaggggcctggctgcctggagcccccatcgcgggggca
cagctgttgggggcgagagaccagtgcccttcttggaagggctgctgggtggggctgacc
ggaggtggggaacgggggctcttctctgcgtatgcccccatgggaggggctgcgcggcca
cctctctcctgcccccaggacctgaagcccagcaatctggcagtgaacgaggactgtgag
ctgaagatcctggacttcggcctggcaaggcaggccgacagcgagatgaccgggtatgtg
gtgacccggtggtaccgggcacccgaggtcatcttgaattggacgcgctacacgcagacg
ggtgagaagctgcccagagacgcagagccgccctggcgccagcctcccgggccacacccc
ccggcttccaattcttcatgggaagtccggggccggctcctccccgggaaggctgctgag
ctgggatgggagcctgtggacatctggtcggcgggctgcatcatggcggagatgatcaca
gggaagacgctgttcaagggcagtgaccacctggaccagctgaaggagatcatgaaggtg
accgggacgcctcctgccgagtttgttcagaggctgcagagtgccgatgcgaagaactac
atgaagggcctccccgagttggagaagaaggattttgcctccatcctgactaatgcaagc
cctctagccgtgaaccttctggagaaaatgctggtgctggatgcagagcggcgggtgact
gcggctgaggcgctgacccacccctacttcgagtcactgcaggacacggaggacgagccc
acggcccagaagtatgatgagtcctttgatgatatggatcacacgctggacgagtggaaa
cgtgtcacatacaaagaagtgctcagcttcaagcctccccggcagctggggaccaaggtc
tccaaggagacggctctgtga
DBGET
integrated database retrieval system