Escherichia marmotae: C1192_22740
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Entry
C1192_22740 CDS
T05353
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ema
Escherichia marmotae
Pathway
ema00230
Purine metabolism
ema01100
Metabolic pathways
ema01110
Biosynthesis of secondary metabolites
Module
ema_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ema00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
C1192_22740
Enzymes [BR:
ema01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
C1192_22740
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Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_N
FGAR-AT_linker
flgK_1st_1
Motif
Other DBs
NCBI-ProteinID:
AUT29608
UniProt:
A0A7L6LDV7
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Position
4452405..4456292
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAARLQVHNIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYVEAGTLT
HEQWQQITAELHDRMMETVFFALDDAKQLFAHHQPAPVTSVDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDYHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDSHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDIPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFA
GHCGIEADIATLGEDRLAALFNEELGAVIQVRAADREAVEGVLAQHGLADCVHYVGQAVS
GDRFVITANGQAVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPFIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSDLWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDSPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcactgtcggcattccgaatcaataaactgctg
gcacgttttcaggctgccaggctccaggttcacaacatttacgccgagtatgtccatttt
gctgacctcaatgcaccgttaaacgatgatgagcacgcgcaacttgaacgcctgctgaaa
tatggcccggcactcgccagccatgccccgcaaggcaaactactgctggtgactccgcgt
cctggcaccatctctccctggtcttcgaaagcgaccgatattgcccataactgcgggctg
caacaggtaaaccgtcttgaacgtggcgttgcttactatgttgaagccggtacgctgact
cacgaacaatggcagcagattaccgctgaactacacgaccgcatgatggaaacggtcttt
tttgcgttagatgatgcaaagcagttgtttgctcatcatcaaccggctccggttaccagc
gttgatttgctgggacaggggcgtcaggccctaatcgacgctaacctgcgtcttggcctg
gcattggcagaagatgagattgactatctgcaagacgctttcacaaagcttggtcgtaac
ccgaacgacatcgagctttatatgttcgcccaggcgaactctgagcactgccgtcacaag
atttttaacgccgactggattatcgacggtgaacaacagccaaaatcgctgttcaagatg
attaaaaacaccttcgaaaccacaccagatcacgttctctctgcatataaagataacgcc
gccgtgatggaaggttccgaagtaggccgctattttgccgaccatgaaacggggcgctac
gattatcatcaggaaccggctcacatcctgatgaaagtggaaacccacaaccacccaacg
gcaatttctccgtggccgggtgcggcgaccggttccggtggtgaaatccgtgatgaaggc
gcaaccggacgcggcgcgaagccgaaagccggcctggttggattctccgtttccaacctg
cgtattccaggctttgaacagccgtgggaagaagattttggtaaaccggaacgtattgtt
accgcactggacattatgaccgaaggcccgctgggcggcgcggcgtttaacaacgaattt
ggccgtccggcactgaacggctacttccgtacttatgaagaaaaagtgaacagccacaat
ggcgaagagctgcgtggttatcacaagccgatcatgctggcgggcgggatcggcaacatc
cgcgccgatcatgtgcagaaaggcgagatcaacgttggtgctaagctcgtcgtcctcggt
ggtccggcaatgaacatcggtcttggcggcggagcggcgtcttctatggcttccggtcag
tctgatgccgacctcgatttcgcctctgtacagcgcgacaaccccgaaatggaacgtcgt
tgccaggaagtgatcgaccgctgctggcagttgggcgatgcaaacccaatcctgtttatc
catgacgttggtgcaggtggtctttctaacgctatgccggaactggtgagtgacggcggg
cgtggcggtaaattcgaattgcgcgatattcttagcgacgaaccggggatgagtccgctg
gaaatctggtgtaacgaatcccaggaacgctacgtgctggccgttgccgccgatcagttg
ccgttgtttgacgaactgtgtaagcgtgaacgcgcgccatatgcggtgattggtgaagca
accgaagaactgcatctttctctgcacgatagtcattttgataatcagccgatcgatctg
ccgctggacgtgttgcttggtaaaacgccgaagatgacccgcgatgtacaaacgctgaaa
gcgaaaggcgacgcgctggttcgtgaagggattactattgctgacgcggtgaaacgcgtg
ctgcatctgccgaccgtggcagagaaaaccttcctcgttaccattggcgaccgtagcgta
accggcatggtggcgcgcgatcagatggtcggtccgtggcaagtaccggtagctaactgt
gcggttactaccgccagcctcgacagctactacggtgaagcaatggcaattggtgaacgt
gcgccggttgcgctgctggattttgccgcctctgctcgtctggcggtcggtgaagcgtta
accaacattgctgctacgcagattggcgatattaaacgcatcaaactttccgccaactgg
atggcggcggcaggccaccctggtgaagatgcgggcctgtatgaagcagtgaaagcggtg
ggcgaagagctttgtccggcgctcggcctgacgatcccggtcggtaaagactctatgtcg
atgaaaacccgctggcaggaaggtaatgaagagcgcgaaatgacctccccgctgtcgctg
gtaatctctgcatttgcccgtgtggaagatgtgcgtcacaccattacgccgcagctttct
accgaagataacgcactgctgctgattgacctcggcaaaggcaataacgcgctgggcgca
acggcgctggcgcaggtatatcgtcagcttggcgatataccggcagatgtgcgcgatgtt
gctcaactgaaaggtttctacgacgccattcaggcgctggtcgcccaacgtaagctgctc
gcctaccacgatcgttctgacggtggcctgttggtgacgctggcggaaatggcgtttgcc
ggtcattgcggcattgaagcagatatcgcaactctgggtgaagatcgcctggccgcgttg
tttaacgaagagctgggggcggtgattcaggtacgcgctgcagaccgtgaagccgtagaa
ggcgtactggcacagcacggacttgctgattgtgtccattatgtcggtcaggctgtttct
ggtgaccgttttgtgattacggccaacgggcaggctgtattcagcgaaagtcgcaccacg
ttgcgtgtctggtgggcagaaaccacctggcagatgcagcgtctgcgtgacaatccggag
tgtgccgatcaggaacaccaggcgaaatctaacgatgccgatccgggtctgaatgtgaaa
ttgtcgttcgatatcaacgaagatgtggcggcaccgtttattgccactggcgcgcgcccg
aaagttgctgtgctgcgtgagcagggtgtgaactcgcatgttgaaatggcggcagcgttc
caccgtgcgggcttcgatgctatcgacgtgcatatgagcgacctgctggctggacgcact
ggcctggaggatttccacgccctggtcgcgtgcggtggtttctcctacggtgacgtgctg
ggcgcaggtgaaggttgggcgaagtctatcctgttcaacgaccgtgtgcgcgatgagttt
gcaaccttcttccatcgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaatctgcgtgaattgatccctggtagtgacctgtggccacgttttgtgcgtaac
acctccgatcgctttgaagcgcgtttcagtctggttgaagtgacccaaagcccgtcactg
ctgttgcaggggatggtgggttcacagatgccgatagctgtttctcacggtgaagggcgc
gtggaagtgcgtgacgctgcgcatctggcggcactggaaagcaaagggctggtggcgctg
cgctatgttgataactttggtaaagtcactgaaacttacccggctaacccgaacggttcc
ccgaacggcattacggcggtcacgactgaaagcggtcgtgtcaccatcatgatgccgcac
ccggaacgtgttttccgcactgtcagcaactcctggcacccggaaaactggggtgaggat
agcccgtggatgcgtattttccgcaatgcgcgtaagcagttggggtaa
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