Eublepharis macularius (Leopard gecko): 129326699
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Entry
129326699 CDS
T09084
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc00010
Glycolysis / Gluconeogenesis
emc00020
Citrate cycle (TCA cycle)
emc00620
Pyruvate metabolism
emc00785
Lipoic acid metabolism
emc01100
Metabolic pathways
emc01200
Carbon metabolism
emc01210
2-Oxocarboxylic acid metabolism
Module
emc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
129326699 (PDHA1)
00020 Citrate cycle (TCA cycle)
129326699 (PDHA1)
00620 Pyruvate metabolism
129326699 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
129326699 (PDHA1)
Enzymes [BR:
emc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
129326699 (PDHA1)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
129326699
NCBI-ProteinID:
XP_054830973
UniProt:
A0AA97KUZ1
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Position
3:70580446..70604253
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AA seq
400 aa
AA seq
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MRKMLLAALSRLLQGSAAHKPGAVSEAARVVVAARNYADFANEASFDIKKYDLHRLEEGP
PTTAIMTREQGLQYYRTMQTIRRMELKADQLYKQKIIRGFCHLYDGQEACCVGLEAAINK
TDHLITAYRGHAFTYTRGVSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ
VPLGAGIALACKYFGKDEICLTLYGDGAANQGQIFETFNMAALWKLPCVFICENNRYGMG
TSVERAAASTDYYKRGDFIPGIRVDGMDVLAVREATKFAADHCRSGKGPVVMELQTYRYH
GHSMSDPGISYRTREEIQEVRSKSDPITLLKDRMVNNNLANVEELKEIDVEVRKHIEDAA
QFATTDPEPSLEELGNFIYSNEPPFEVRGANQWIRYKSAG
NT seq
1203 nt
NT seq
+upstream
nt +downstream
nt
atgcgcaagatgctgctggccgcgctctcccgtctcctgcaaggctccgctgcccacaag
ccgggagctgttagtgaggctgctcgtgtggttgtcgcagctcgtaactatgcagatttt
gcaaatgaggcttcgtttgacattaagaaatatgatcttcatcgcttggaggaaggtcca
cccactacagcaattatgactcgagagcaaggtctgcagtactacaggactatgcagact
attcggcgtatggaactgaaagcagaccagttgtacaaacagaagattatccgtggcttc
tgtcatttatatgatggtcaggaggcctgctgtgttggacttgaggctgccataaataaa
acagatcatttgatcactgcttaccggggtcatgcctttacatatacacgtggtgtttct
gttcgtgaaatccttgctgagctcacaggtcgaaaaggtggatgtgccaaaggcaaagga
ggctctatgcatatgtatgccaaaaacttctatggtggtaatggtattgttggtgcccag
gttcctttgggagctggcattgccttagcatgcaagtattttggcaaagatgaaatctgc
ctgacattatatggagatggtgctgccaatcagggtcagatatttgaaacatttaatatg
gcagccttgtggaagctgccatgcgtttttatctgcgagaacaacagatatggaatgggt
acgtcggtagaaagagctgcagccagtacagactattataaaaggggagacttcattcca
ggaattagagttgatggtatggatgttcttgctgtaagggaagcaacaaaatttgctgct
gaccattgcagatccggcaaaggtcctgttgtgatggagctacagacatatcgttatcat
ggacacagtatgagtgatcctggcatcagttaccgtacaagagaagaaattcaagaagta
agaagcaaaagtgatcctattactctcctcaaggacagaatggtgaacaacaacttagct
aatgtggaagagctaaaggagattgatgtggaagtaaggaagcacattgaagatgcagct
cagtttgctacaacggatccagaaccatctcttgaagaactaggcaatttcatctatagt
aatgagccaccttttgaggtgcgtggcgcaaatcagtggattcggtacaaatctgctggc
taa
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