Equus przewalskii (Przewalski's horse): 103542533
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Entry
103542533 CDS
T04644
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase (lipoamide) alpha 1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
epz
Equus przewalskii (Przewalski's horse)
Pathway
epz00010
Glycolysis / Gluconeogenesis
epz00020
Citrate cycle (TCA cycle)
epz00620
Pyruvate metabolism
epz00785
Lipoic acid metabolism
epz01100
Metabolic pathways
epz01200
Carbon metabolism
epz01210
2-Oxocarboxylic acid metabolism
epz04066
HIF-1 signaling pathway
epz04922
Glucagon signaling pathway
epz05230
Central carbon metabolism in cancer
epz05415
Diabetic cardiomyopathy
Module
epz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
epz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
103542533 (PDHA1)
00020 Citrate cycle (TCA cycle)
103542533 (PDHA1)
00620 Pyruvate metabolism
103542533 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
103542533 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
103542533 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
103542533 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
103542533 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
103542533 (PDHA1)
Enzymes [BR:
epz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
103542533 (PDHA1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
103542533
NCBI-ProteinID:
XP_008507693
LinkDB
All DBs
Position
Un
AA seq
384 aa
AA seq
DB search
IKSTDICIFWSFKASRVLVASRSFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLRYYR
MMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFT
RGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYFGK
DEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRG
DFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREE
IQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGH
HIYSSDPPFEVRGANQWIKFKSIS
NT seq
1155 nt
NT seq
+upstream
nt +downstream
nt
ataaaaagtactgatatttgtatattttggtctttcaaggcaagcagagtgctggtggcc
tcccgtagttttgcaaacgatgctacgtttgaaattaagaaatgtgatctacaccggctg
gaagagggccctcctgtcacgacagtgctcaccagggaggacgggctcagatactacagg
atgatgcagactgtccgccgaatggagttaaaggcagatcagctgtataaacagaaaatt
attcgtggtttctgtcacttgtgtgatggtcaggaagcttgttgtgtgggcctggaggcc
ggcatcaaccccacagaccatcttatcacagcctatcgggctcacggctttacctttact
cgtgggctgtctgtccgagaaattctcgccgagcttacaggacgaagaggaggttgtgct
aaaggaaaaggaggatcgatgcatatgtatgccaagaacttctacgggggcaatggcatt
gtcggagctcaggtgcccctgggagctgggattgctctggcctgtaagtattttggaaaa
gatgaggtctgtttgactttatatggcgatggtgctgctaatcagggtcagatattcgaa
gcttacaatatggcggctttgtggaaattgccttgtattttcatctgtgaaaataaccgc
tatggaatgggaacttctgttgagagagcagcagccagcactgattattacaagagaggt
gacttcatccctgggctgagggtagatggaatggatatcctgtgtgtccgggaggcgaca
aggtttgcagctgcctattgtagatctggaaaggggcccatactgatggagctgcagact
taccgttaccatggacacagcatgagtgatcctggagtcagttatcgtacacgagaagaa
attcaggaagtaagaagtaagagtgaccctatcatgcttctcaaggatagaatggtgaac
agcaaccttgccagtgttgaagaattaaaggaaattgatgttgaagtgaggaaagaaatt
gaggatgccgcccagtttgccacagctgatcccgaaccacctttggaagaactaggccat
cacatctacagcagtgatccgccttttgaagttcgcggtgcaaatcagtggatcaagttt
aagtccatcagttaa
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