KEGG   Echinops telfairi (small Madagascar hedgehog): 101653940
Entry
101653940         CDS       T08707                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
etf  Echinops telfairi (small Madagascar hedgehog)
Pathway
etf01522  Endocrine resistance
etf04010  MAPK signaling pathway
etf04015  Rap1 signaling pathway
etf04068  FoxO signaling pathway
etf04071  Sphingolipid signaling pathway
etf04114  Oocyte meiosis
etf04148  Efferocytosis
etf04218  Cellular senescence
etf04261  Adrenergic signaling in cardiomyocytes
etf04370  VEGF signaling pathway
etf04380  Osteoclast differentiation
etf04550  Signaling pathways regulating pluripotency of stem cells
etf04611  Platelet activation
etf04613  Neutrophil extracellular trap formation
etf04620  Toll-like receptor signaling pathway
etf04621  NOD-like receptor signaling pathway
etf04622  RIG-I-like receptor signaling pathway
etf04625  C-type lectin receptor signaling pathway
etf04657  IL-17 signaling pathway
etf04658  Th1 and Th2 cell differentiation
etf04659  Th17 cell differentiation
etf04660  T cell receptor signaling pathway
etf04664  Fc epsilon RI signaling pathway
etf04668  TNF signaling pathway
etf04670  Leukocyte transendothelial migration
etf04714  Thermogenesis
etf04722  Neurotrophin signaling pathway
etf04723  Retrograde endocannabinoid signaling
etf04728  Dopaminergic synapse
etf04750  Inflammatory mediator regulation of TRP channels
etf04912  GnRH signaling pathway
etf04914  Progesterone-mediated oocyte maturation
etf04917  Prolactin signaling pathway
etf04926  Relaxin signaling pathway
etf04932  Non-alcoholic fatty liver disease
etf04933  AGE-RAGE signaling pathway in diabetic complications
etf04935  Growth hormone synthesis, secretion and action
etf04936  Alcoholic liver disease
etf05014  Amyotrophic lateral sclerosis
etf05020  Prion disease
etf05022  Pathways of neurodegeneration - multiple diseases
etf05132  Salmonella infection
etf05133  Pertussis
etf05135  Yersinia infection
etf05140  Leishmaniasis
etf05142  Chagas disease
etf05145  Toxoplasmosis
etf05152  Tuberculosis
etf05161  Hepatitis B
etf05163  Human cytomegalovirus infection
etf05167  Kaposi sarcoma-associated herpesvirus infection
etf05169  Epstein-Barr virus infection
etf05170  Human immunodeficiency virus 1 infection
etf05171  Coronavirus disease - COVID-19
etf05205  Proteoglycans in cancer
etf05208  Chemical carcinogenesis - reactive oxygen species
etf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
etf05415  Diabetic cardiomyopathy
etf05417  Lipid and atherosclerosis
etf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:etf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101653940 (MAPK12)
   04015 Rap1 signaling pathway
    101653940 (MAPK12)
   04370 VEGF signaling pathway
    101653940 (MAPK12)
   04668 TNF signaling pathway
    101653940 (MAPK12)
   04068 FoxO signaling pathway
    101653940 (MAPK12)
   04071 Sphingolipid signaling pathway
    101653940 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101653940 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    101653940 (MAPK12)
   04218 Cellular senescence
    101653940 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101653940 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101653940 (MAPK12)
   04613 Neutrophil extracellular trap formation
    101653940 (MAPK12)
   04620 Toll-like receptor signaling pathway
    101653940 (MAPK12)
   04621 NOD-like receptor signaling pathway
    101653940 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    101653940 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    101653940 (MAPK12)
   04660 T cell receptor signaling pathway
    101653940 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    101653940 (MAPK12)
   04659 Th17 cell differentiation
    101653940 (MAPK12)
   04657 IL-17 signaling pathway
    101653940 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    101653940 (MAPK12)
   04670 Leukocyte transendothelial migration
    101653940 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101653940 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    101653940 (MAPK12)
   04917 Prolactin signaling pathway
    101653940 (MAPK12)
   04926 Relaxin signaling pathway
    101653940 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    101653940 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101653940 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    101653940 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    101653940 (MAPK12)
   04722 Neurotrophin signaling pathway
    101653940 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101653940 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101653940 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    101653940 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101653940 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    101653940 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101653940 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101653940 (MAPK12)
   05161 Hepatitis B
    101653940 (MAPK12)
   05171 Coronavirus disease - COVID-19
    101653940 (MAPK12)
   05163 Human cytomegalovirus infection
    101653940 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101653940 (MAPK12)
   05169 Epstein-Barr virus infection
    101653940 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101653940 (MAPK12)
   05135 Yersinia infection
    101653940 (MAPK12)
   05133 Pertussis
    101653940 (MAPK12)
   05152 Tuberculosis
    101653940 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101653940 (MAPK12)
   05140 Leishmaniasis
    101653940 (MAPK12)
   05142 Chagas disease
    101653940 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101653940 (MAPK12)
   05020 Prion disease
    101653940 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    101653940 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101653940 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    101653940 (MAPK12)
   05415 Diabetic cardiomyopathy
    101653940 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101653940 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    101653940 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101653940 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101653940 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:etf01001]
    101653940 (MAPK12)
Enzymes [BR:etf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101653940 (MAPK12)
Protein kinases [BR:etf01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101653940 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH UvrD_C Kinase-like Haspin_kinase
Other DBs
NCBI-GeneID: 101653940
NCBI-ProteinID: XP_004700273
LinkDB
Position
Unknown
AA seq 287 aa
MQHENVIGLLDVFTPDETLDEFTDFYLVMPFMGTDLGKLMKHEKLTEDRIQFLVYQMLKG
LKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNW
MRYTQTVDIWSVGCIMAEMITGKTLFKGNDHLDQLKEIMKVTGTPPAEFVQRLQSADAKN
YMKGLPELEKKDFASVLTNASPLAVSLLEKMLVLDAEQRVTAAAALAHPYFEALHDTEDE
TAVQKYDDSFDDMDRTLDEWKRVTYKEVLSFRPPQQLESRVSKETAL
NT seq 864 nt   +upstreamnt  +downstreamnt
atgcagcacgagaacgtgatcggactcctggatgtgttcactcctgacgagactctggac
gagttcacagacttttacctggtgatgcccttcatggggacagacctgggcaaactcatg
aaacatgaaaagctgaccgaggaccgcatccagttcctggtctaccagatgctcaaaggg
ctcaagtacatccatgcggctggtgtcatccacagggacctgaagccaggcaacctggca
gtgaatgaggactgtgaactgaagatcctggactttggcctggccaggcaggcggacagt
gagatgacggggtacgtggtgacacggtggtacagagcaccggaagtcatcctgaattgg
atgcgctacactcagacagtggatatctggtccgtgggctgcattatggccgagatgatc
actgggaagacgctgtttaagggcaacgaccacctggaccagctcaaggagatcatgaag
gtcacggggacgcccccagccgagtttgtgcagcggctgcagagcgcagatgccaagaac
tacatgaaaggccttccggaattggagaagaaggattttgcctcagtcctgaccaacgcc
agccccctggctgtgagcctgctggagaagatgctggtgctggatgccgagcagcgggtg
actgcggcagcagcgctggcacacccctactttgaggccctgcatgacacggaggacgag
acagccgtacagaagtacgacgactcctttgacgacatggaccgcacgctggacgagtgg
aagcgtgtcacctataaagaggtgctcagcttcaggcctccccagcagctggagtccagg
gtctccaaggagacggccctgtga

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